| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | 0.0793519 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0591761 |
| FAM13A | family with sequence similarity 13, member A | 0.0416579 |
| TMF1 | TATA element modulatory factor 1 | 0.0394777 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.032853 |
| SRP54 | signal recognition particle 54kDa | 0.0327538 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0323759 |
| POTEF | POTE ankyrin domain family, member F | 0.0303744 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.030131 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0287239 |
| HYOU1 | hypoxia up-regulated 1 | 0.0278485 |
| SETD5 | SET domain containing 5 | 0.0263756 |
| CTTN | cortactin | 0.0261524 |
| CDK19 | cyclin-dependent kinase 19 | 0.0254425 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0250133 |
| RPS12 | ribosomal protein S12 | 0.0246187 |
| ZNF292 | zinc finger protein 292 | 0.0238861 |
| PGM3 | phosphoglucomutase 3 | 0.0236097 |
| HKDC1 | hexokinase domain containing 1 | 0.0235504 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.022363 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0222724 |
| DSG2 | desmoglein 2 | 0.0220066 |
| PCBP2 | poly(rC) binding protein 2 | 0.0219876 |
| HELZ | helicase with zinc finger | 0.0217206 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0213467 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0211967 |
| GOLGA4 | golgin A4 | 0.0208911 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0208215 |
| FNIP1 | folliculin interacting protein 1 | 0.020586 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0201246 |
| ZNF706 | zinc finger protein 706 | 0.0200921 |
| AREG | amphiregulin | 0.0195022 |
| RNF145 | ring finger protein 145 | 0.0192519 |
| CCNY | cyclin Y | 0.019126 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0190833 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.019009 |
| LYZ | lysozyme | 0.0189019 |
| AKAP17A | A kinase (PRKA) anchor protein 17A | 0.0183831 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0183822 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0182354 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0182341 |
| TPM3 | tropomyosin 3 | 0.0180599 |
| PAPOLA | poly(A) polymerase alpha | 0.0179653 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0178262 |
| RPS2 | ribosomal protein S2 | 0.0177586 |
| COG6 | component of oligomeric golgi complex 6 | 0.0176826 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0176634 |
| DSTN | destrin (actin depolymerizing factor) | 0.0174733 |
| PSMB1 | proteasome (prosome, macropain) subunit, beta type, 1 | 0.0171894 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0171587 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0171467 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0170696 |
| VEGFA | vascular endothelial growth factor A | 0.0169867 |
| TXNIP | thioredoxin interacting protein | 0.016808 |
| CCNC | cyclin C | 0.0167715 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0166501 |
| NBR1 | neighbor of BRCA1 gene 1 | 0.0166292 |
| RIOK3 | RIO kinase 3 | 0.0166242 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0165897 |
| RPS3 | ribosomal protein S3 | 0.0164158 |
| FAM135A | family with sequence similarity 135, member A | 0.0163058 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0160673 |
| SNX3 | sorting nexin 3 | 0.0159758 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | 0.0159164 |
| S100P | S100 calcium binding protein P | 0.0158403 |
| BRD4 | bromodomain containing 4 | 0.0156228 |
| RPL37A | ribosomal protein L37a | 0.0155979 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0155407 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0154516 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0154187 |
| BRD2 | bromodomain containing 2 | 0.0151138 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0148559 |
| RPL3 | ribosomal protein L3 | 0.0148527 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0148247 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0145892 |
| TBC1D8B | TBC1 domain family, member 8B (with GRAM domain) | 0.0143706 |
| PRR13 | proline rich 13 | 0.0140465 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | 0.0139726 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | 0.0139269 |
| AHCYL1 | adenosylhomocysteinase-like 1 | 0.0138726 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0138339 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0137243 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0136998 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | 0.0136921 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0136505 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0135631 |
| UBN2 | ubinuclein 2 | 0.0135575 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0134498 |
| DNAJB9 | DnaJ (Hsp40) homolog, subfamily B, member 9 | 0.0133696 |
| RPS7 | ribosomal protein S7 | 0.0133621 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | 0.0132473 |
| RPL18 | ribosomal protein L18 | 0.0132379 |
| PNN | pinin, desmosome associated protein | 0.013221 |
| MMADHC | methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria | 0.0132207 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0132096 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0128926 |
| MUC3B | mucin 3B, cell surface associated | 0.01288 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0128416 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0128069 |
| ANXA1 | annexin A1 | 0.012767 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GMDS | GDP-mannose 4,6-dehydratase | -0.196057 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.181761 |
| TMSB10 | thymosin beta 10 | -0.138029 |
| LOC112694756 | uncharaterized LOC112694756 | -0.10127 |
| LMO7 | LIM domain 7 | -0.0996553 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0946201 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0892875 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0739755 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0735036 |
| RPL35A | ribosomal protein L35a | -0.0734513 |
| EMP1 | epithelial membrane protein 1 | -0.065099 |
| EZR | ezrin | -0.0609148 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0603035 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0583534 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0564363 |
| RNF213 | ring finger protein 213 | -0.0543974 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0539077 |
| AGR2 | anterior gradient 2 | -0.0538631 |
| RRBP1 | ribosome binding protein 1 | -0.053137 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0507427 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0488576 |
| ACTN4 | actinin, alpha 4 | -0.0475242 |
| HLA-C | major histocompatibility complex, class I, C | -0.0444667 |
| FAT1 | FAT atypical cadherin 1 | -0.0440764 |
| COBL | cordon-bleu WH2 repeat protein | -0.0438638 |
| TXNRD1 | thioredoxin reductase 1 | -0.0432999 |
| RPL23 | ribosomal protein L23 | -0.0420824 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0414434 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | -0.0410337 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0408952 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.040384 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0401761 |
| HMGB1 | high mobility group box 1 | -0.0395471 |
| AHNAK | AHNAK nucleoprotein | -0.039229 |
| ANXA2 | annexin A2 | -0.038931 |
| PLSCR1 | phospholipid scramblase 1 | -0.0385855 |
| H1-0 | H1.0 linker histone | -0.0376827 |
| GPX2 | glutathione peroxidase 2 | -0.0370312 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0366606 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0365773 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0362726 |
| SP100 | SP100 nuclear antigen | -0.0362066 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0357954 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0357312 |
| PRSS3 | protease, serine, 3 | -0.0355611 |
| TJP1 | tight junction protein 1 | -0.0355576 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0350462 |
| TMEM123 | transmembrane protein 123 | -0.0349107 |
| CANX | calnexin | -0.0347722 |
| ARF1 | ADP-ribosylation factor 1 | -0.0336696 |
| AOPEP | aminopeptidase O (putative) | -0.0331883 |
| PRKCA | protein kinase C, alpha | -0.0330941 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0327722 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.032649 |
| ETV6 | ets variant 6 | -0.0324901 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0324574 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0324572 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0314687 |
| SH3RF1 | SH3 domain containing ring finger 1 | -0.0307078 |
| RBM39 | RNA binding motif protein 39 | -0.0301436 |
| RPS21 | ribosomal protein S21 | -0.0300016 |
| HMGA1 | high mobility group AT-hook 1 | -0.0298319 |
| RPL38 | ribosomal protein L38 | -0.0285156 |
| CD2AP | CD2-associated protein | -0.0279912 |
| S100A6 | S100 calcium binding protein A6 | -0.0278455 |
| SULF2 | sulfatase 2 | -0.0278027 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0276153 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0276098 |
| ECT2 | epithelial cell transforming 2 | -0.0270522 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0263517 |
| KLF6 | Kruppel-like factor 6 | -0.0262946 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0262032 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0261891 |
| RUNX1 | runt-related transcription factor 1 | -0.0261818 |
| EPCAM | epithelial cell adhesion molecule | -0.0261361 |
| INSIG1 | insulin induced gene 1 | -0.0259805 |
| SMAD3 | SMAD family member 3 | -0.0258572 |
| DEK | DEK proto-oncogene | -0.0258112 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0258055 |
| LCN2 | lipocalin 2 | -0.0255842 |
| FASN | fatty acid synthase | -0.025372 |
| TCF12 | transcription factor 12 | -0.0253563 |
| CCT6A | chaperonin containing TCP1, subunit 6A (zeta 1) | -0.025246 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0251908 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0250538 |
| EHBP1 | EH domain binding protein 1 | -0.0250429 |
| PHF14 | PHD finger protein 14 | -0.024856 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0246631 |
| WDR45B | WD repeat domain 45B | -0.0244634 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0244187 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0242978 |
| RPS24 | ribosomal protein S24 | -0.024256 |
| MYO1D | myosin ID | -0.0241995 |
| LDHA | lactate dehydrogenase A | -0.0241345 |
| PRRC2B | proline-rich coiled-coil 2B | -0.0235604 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0235242 |
| ABCC3 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 | -0.0234459 |
| EGR1 | early growth response 1 | -0.0231052 |
| MTUS1 | microtubule associated tumor suppressor 1 | -0.023035 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0230227 |
