| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.0455291 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0378469 |
| RPS12 | ribosomal protein S12 | 0.0271676 |
| MT2A | metallothionein 2A | 0.0257076 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0241173 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0232282 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0227414 |
| EFNA5 | ephrin-A5 | 0.0225487 |
| RPS2 | ribosomal protein S2 | 0.0215633 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0195892 |
| H1-4 | H1.4 linker histone, cluster member | 0.01877 |
| RPL4 | ribosomal protein L4 | 0.0183364 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0179507 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0178382 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0177552 |
| PRELID2 | PRELI domain containing 2 | 0.0176938 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.017138 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.01574 |
| TPM3 | tropomyosin 3 | 0.0153272 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0152587 |
| BDNF | brain-derived neurotrophic factor | 0.0150722 |
| NCKAP1 | NCK-associated protein 1 | 0.0137577 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0137415 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0136135 |
| RPL37A | ribosomal protein L37a | 0.0132616 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0132088 |
| NLGN1 | neuroligin 1 | 0.0130361 |
| VCL | vinculin | 0.0125785 |
| RPL6 | ribosomal protein L6 | 0.0125172 |
| ZNF292 | zinc finger protein 292 | 0.0120973 |
| WDR26 | WD repeat domain 26 | 0.012004 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0120031 |
| PGK1 | phosphoglycerate kinase 1 | 0.0119544 |
| PRKD1 | protein kinase D1 | 0.0117457 |
| RPL3 | ribosomal protein L3 | 0.0114894 |
| SMYD3 | SET and MYND domain containing 3 | 0.0114066 |
| WWOX | WW domain containing oxidoreductase | 0.0112199 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0106235 |
| RPS7 | ribosomal protein S7 | 0.0103438 |
| PAPOLA | poly(A) polymerase alpha | 0.0102458 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0102445 |
| ENO1 | enolase 1, (alpha) | 0.0102084 |
| PRKCE | protein kinase C, epsilon | 0.0100832 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0100445 |
| RPL9 | ribosomal protein L9 | 0.0100427 |
| SMAP1 | small ArfGAP 1 | 0.00994591 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.00990394 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.00976778 |
| NEK7 | NIMA-related kinase 7 | 0.0097495 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.00973506 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.00959385 |
| RAD51B | RAD51 paralog B | 0.00958154 |
| RPS17 | ribosomal protein S17 | 0.00954396 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.00945916 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.00940466 |
| CORO1C | coronin, actin binding protein, 1C | 0.00893562 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.00880319 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.00872952 |
| ANKRD36 | ankyrin repeat domain 36 | 0.00865676 |
| PHC2 | polyhomeotic homolog 2 (Drosophila) | 0.00832739 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.00829628 |
| KHDRBS3 | KH domain containing, RNA binding, signal transduction associated 3 | 0.00828307 |
| EIF4A3 | eukaryotic translation initiation factor 4A3 | 0.00816632 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0081357 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.00811619 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | 0.00810429 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.00802018 |
| NTNG2 | netrin G2 | 0.00793268 |
| RPL27 | ribosomal protein L27 | 0.00787027 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.00781179 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.00781001 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.00779879 |
| CLTC | clathrin, heavy chain (Hc) | 0.0077647 |
| H1-2 | H1.2 linker histone, cluster member | 0.007641 |
| MARCHF4 | membrane associated ring-CH-type finger 4 | 0.0075525 |
| RRM2 | ribonucleotide reductase M2 | 0.00754519 |
| FLNB | filamin B, beta | 0.00737649 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.00733784 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.00730844 |
| DAPK3 | death-associated protein kinase 3 | 0.00720227 |
| FHIT | fragile histidine triad | 0.00717966 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.00706577 |
| NAV1 | neuron navigator 1 | 0.00698957 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.00697936 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.00697367 |
| CAPN2 | calpain 2, (m/II) large subunit | 0.00692831 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.00692329 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.00692119 |
| RPS3A | ribosomal protein S3A | 0.00689395 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.00689001 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.00688635 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.00687518 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.00687135 |
| TMEM39A | transmembrane protein 39A | 0.00687052 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.00686595 |
| FLRT2 | fibronectin leucine rich transmembrane protein 2 | 0.00686292 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.00686025 |
| MALT1 | MALT1 paracaspase | 0.0068385 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.00678111 |
| GALNT1 | polypeptide N-acetylgalactosaminyltransferase 1 | 0.00671709 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.222904 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.172608 |
| MMP12 | matrix metallopeptidase 12 | -0.14084 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.126863 |
| LSAMP | limbic system-associated membrane protein | -0.091402 |
| TMSB10 | thymosin beta 10 | -0.0885793 |
| EGR1 | early growth response 1 | -0.0880837 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0859294 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0631046 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0630044 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0609896 |
| DST | dystonin | -0.0576156 |
| FN1 | fibronectin 1 | -0.0562082 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0510592 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0501006 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0482532 |
| LDHA | lactate dehydrogenase A | -0.0459335 |
| CD109 | CD109 molecule | -0.0458405 |
| LOC112694756 | uncharaterized LOC112694756 | -0.041947 |
| JMJD1C | jumonji domain containing 1C | -0.0408509 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.040747 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0393354 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0384867 |
| YBX3 | Y box binding protein 3 | -0.038065 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0378545 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0378228 |
| HDAC9 | histone deacetylase 9 | -0.0374411 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0374121 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.037287 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0368367 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0365427 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0360568 |
| NF1 | neurofibromin 1 | -0.0356088 |
| JUN | jun proto-oncogene | -0.0355881 |
| RUNX1 | runt-related transcription factor 1 | -0.0354157 |
| PTCHD4 | patched domain containing 4 | -0.0353395 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0351137 |
| CTSB | cathepsin B | -0.0348696 |
| ERBIN | erbb2 interacting protein | -0.0346768 |
| MYO10 | myosin X | -0.034668 |
| HMGA1 | high mobility group AT-hook 1 | -0.03432 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0328072 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0327698 |
| HAS2 | hyaluronan synthase 2 | -0.032698 |
| TXNIP | thioredoxin interacting protein | -0.0324335 |
| BPTF | bromodomain PHD finger transcription factor | -0.0317689 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0316764 |
| TXNRD1 | thioredoxin reductase 1 | -0.0313996 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0307934 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0297525 |
| PARD3 | par-3 family cell polarity regulator | -0.0293836 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0290153 |
| KYNU | kynureninase | -0.0288265 |
| SPAG9 | sperm associated antigen 9 | -0.0287586 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0287518 |
| RPS6 | ribosomal protein S6 | -0.0286971 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0286165 |
| MAP4 | microtubule-associated protein 4 | -0.0281894 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0281371 |
| LIMA1 | LIM domain and actin binding 1 | -0.0280353 |
| CD44 | CD44 molecule (Indian blood group) | -0.0276114 |
| RPL35A | ribosomal protein L35a | -0.0274727 |
| NTM | neurotrimin | -0.0269914 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.026926 |
| FOXP1 | forkhead box P1 | -0.026914 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0268134 |
| SBF2 | SET binding factor 2 | -0.0264704 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0264182 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.025911 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0257792 |
| PTK2 | protein tyrosine kinase 2 | -0.0256812 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0251812 |
| PKM | pyruvate kinase, muscle | -0.0251802 |
| RAI14 | retinoic acid induced 14 | -0.0249797 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.024926 |
| C2CD2 | C2 calcium-dependent domain containing 2 | -0.0246025 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0244728 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0244388 |
| TPM4 | tropomyosin 4 | -0.0237253 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0236311 |
| NDRG1 | N-myc downstream regulated 1 | -0.0234934 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0234805 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0233614 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0230416 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0228091 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0226473 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0224385 |
| USP34 | ubiquitin specific peptidase 34 | -0.0224044 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0221244 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0220882 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0220363 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0219592 |
| WDR45B | WD repeat domain 45B | -0.0214643 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0212137 |
| TAOK1 | TAO kinase 1 | -0.021182 |
| RCAN1 | regulator of calcineurin 1 | -0.0211787 |
| ANXA2 | annexin A2 | -0.0209118 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0207849 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0206237 |
| APP | amyloid beta (A4) precursor protein | -0.0205321 |
