| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.111549 |
| EREG | epiregulin | 0.10101 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0917839 |
| RNF43 | ring finger protein 43 | 0.086958 |
| TNS4 | tensin 4 | 0.0710646 |
| PRELID2 | PRELI domain containing 2 | 0.0666326 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0590176 |
| NDRG1 | N-myc downstream regulated 1 | 0.0572017 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.0533363 |
| TXNIP | thioredoxin interacting protein | 0.0502107 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.049566 |
| RNF145 | ring finger protein 145 | 0.0460667 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | 0.0455322 |
| GPHN | gephyrin | 0.0443191 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0428832 |
| SETD5 | SET domain containing 5 | 0.0419741 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.041568 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0413404 |
| PTMA | prothymosin, alpha | 0.0386547 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0384615 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0383738 |
| GOLGA4 | golgin A4 | 0.0366158 |
| INSIG1 | insulin induced gene 1 | 0.0364071 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0351928 |
| RPS2 | ribosomal protein S2 | 0.0350688 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0349438 |
| H1-0 | H1.0 linker histone | 0.0338968 |
| CCNY | cyclin Y | 0.0329932 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0322331 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0319608 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0319339 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.03121 |
| ANXA2 | annexin A2 | 0.0311292 |
| ABHD17C | abhydrolase domain containing 17C | 0.0310682 |
| RPL6 | ribosomal protein L6 | 0.030572 |
| ZNF292 | zinc finger protein 292 | 0.0304684 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0302717 |
| ONECUT3 | one cut homeobox 3 | 0.0298619 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.029828 |
| H1-4 | H1.4 linker histone, cluster member | 0.0294579 |
| THOC2 | THO complex 2 | 0.0285976 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | 0.0285393 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0283354 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0281336 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.027879 |
| DSG2 | desmoglein 2 | 0.0277481 |
| ETNK1 | ethanolamine kinase 1 | 0.0268766 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.026811 |
| CDK19 | cyclin-dependent kinase 19 | 0.0266957 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.026047 |
| WASF2 | WAS protein family, member 2 | 0.0260392 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0258236 |
| CDC42SE2 | CDC42 small effector 2 | 0.025659 |
| NFIA | nuclear factor I/A | 0.0254077 |
| PKP2 | plakophilin 2 | 0.0251741 |
| SRP54 | signal recognition particle 54kDa | 0.0245091 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0244155 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0243194 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0238115 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0237306 |
| EXOC1 | exocyst complex component 1 | 0.0237223 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0237071 |
| CDC73 | cell division cycle 73 | 0.0236154 |
| PCDHB16 | protocadherin beta 16 | 0.0234921 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0234759 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0234691 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0234179 |
| TRIM2 | tripartite motif containing 2 | 0.0233194 |
| S100P | S100 calcium binding protein P | 0.0231354 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0227464 |
| DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 | 0.0227338 |
| SFXN1 | sideroflexin 1 | 0.0227243 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0227155 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | 0.0225786 |
| TBC1D5 | TBC1 domain family, member 5 | 0.0224638 |
| ESRP1 | epithelial splicing regulatory protein 1 | 0.0221962 |
| NCKAP1 | NCK-associated protein 1 | 0.0219453 |
| PNN | pinin, desmosome associated protein | 0.0218008 |
| ETS2 | v-ets avian erythroblastosis virus E26 oncogene homolog 2 | 0.0216763 |
| PLEK2 | pleckstrin 2 | 0.0215289 |
| GLCE | glucuronic acid epimerase | 0.0213663 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.021343 |
| MED13L | mediator complex subunit 13-like | 0.0212451 |
| ZFR | zinc finger RNA binding protein | 0.0210488 |
| CENPF | centromere protein F, 350/400kDa | 0.0210206 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.020996 |
| CCNC | cyclin C | 0.0208667 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0207969 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0207256 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0207227 |
| FERMT1 | fermitin family member 1 | 0.0206359 |
| SUCO | SUN domain containing ossification factor | 0.0205835 |
| USP3 | ubiquitin specific peptidase 3 | 0.0205722 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0205239 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | 0.0205219 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0204126 |
| NUP58 | nucleoporin 58 | 0.0203823 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0202795 |
| FDPS | farnesyl diphosphate synthase | 0.0202791 |
| HELZ | helicase with zinc finger | 0.0202429 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB10 | thymosin beta 10 | -0.243493 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.172362 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.144585 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.124038 |
| MYO1E | myosin IE | -0.12372 |
| LMO7 | LIM domain 7 | -0.120198 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.119331 |
| UBC | ubiquitin C | -0.119283 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.102442 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0955016 |
| FAT1 | FAT atypical cadherin 1 | -0.085525 |
| LDHA | lactate dehydrogenase A | -0.0852707 |
| RPS27A | ribosomal protein S27a | -0.0846835 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0817003 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0801951 |
| MT2A | metallothionein 2A | -0.0780046 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0776935 |
| AHNAK | AHNAK nucleoprotein | -0.0750922 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0749611 |
| ITGA6 | integrin, alpha 6 | -0.0714609 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0669531 |
| S100A6 | S100 calcium binding protein A6 | -0.0661632 |
| EZR | ezrin | -0.0645264 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0639879 |
| ASPH | aspartate beta-hydroxylase | -0.0614927 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0575427 |
| ENO1 | enolase 1, (alpha) | -0.0572947 |
| RPL23 | ribosomal protein L23 | -0.0572254 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0571892 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0544601 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0530032 |
| PKM | pyruvate kinase, muscle | -0.052753 |
| JUN | jun proto-oncogene | -0.0518377 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0506142 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0503823 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0478402 |
| HMGA1 | high mobility group AT-hook 1 | -0.0473474 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0465611 |
| MUC17 | mucin 17, cell surface associated | -0.0460143 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | -0.0455507 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0451703 |
| FTL | ferritin, light polypeptide | -0.043442 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0421712 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.041116 |
| TPM4 | tropomyosin 4 | -0.0410335 |
| LAMA4 | laminin, alpha 4 | -0.0410046 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0404196 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0396749 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0385356 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0380831 |
| LMNA | lamin A/C | -0.0379735 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0378411 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0378097 |
| PCBP2 | poly(rC) binding protein 2 | -0.0376768 |
| MT1X | metallothionein 1X | -0.0375481 |
| EGFR | epidermal growth factor receptor | -0.0374065 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0369505 |
| FBXO11 | F-box protein 11 | -0.0364514 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0362858 |
| EMP1 | epithelial membrane protein 1 | -0.0359305 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0357957 |
| RPL35A | ribosomal protein L35a | -0.03558 |
| MED13 | mediator complex subunit 13 | -0.0353617 |
| SVIL | supervillin | -0.0351528 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0350308 |
| TFF1 | trefoil factor 1 | -0.0349054 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0348677 |
| YBX1 | Y box binding protein 1 | -0.0348093 |
| ACTG1 | actin gamma 1 | -0.0342544 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0337807 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0332964 |
| MARCHF3 | membrane associated ring-CH-type finger 3 | -0.0330508 |
| POTEF | POTE ankyrin domain family, member F | -0.0329569 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0323515 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.032178 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0318229 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0317898 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0317762 |
| RPLP1 | ribosomal protein, large, P1 | -0.031484 |
| ANXA1 | annexin A1 | -0.0314135 |
| ACTN4 | actinin, alpha 4 | -0.0313043 |
| MYO5B | myosin VB | -0.0310191 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.030864 |
| CANX | calnexin | -0.0306843 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0306162 |
| TJP1 | tight junction protein 1 | -0.0302279 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0298753 |
| SFPQ | splicing factor proline/glutamine-rich | -0.029789 |
| RPS8 | ribosomal protein S8 | -0.0296137 |
| GAREM1 | GRB2 associated regulator of MAPK1 subtype 1 | -0.0295982 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0295274 |
| RIGI | RNA sensor RIG-I | -0.0295006 |
| RPS6 | ribosomal protein S6 | -0.0294058 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | -0.0292902 |
| CCND1 | cyclin D1 | -0.0286809 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0286424 |
| CALR | calreticulin | -0.0282937 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0282823 |
| RPL9 | ribosomal protein L9 | -0.0282389 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0281945 |
