| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0411247 |
| LOXL2 | lysyl oxidase-like 2 | 0.0247717 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0199567 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0197844 |
| PODXL | podocalyxin-like | 0.0194775 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.019291 |
| HELZ | helicase with zinc finger | 0.0192456 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0184712 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0183175 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0182292 |
| CCNL1 | cyclin L1 | 0.0171698 |
| FOSL1 | FOS-like antigen 1 | 0.0166402 |
| NDRG1 | N-myc downstream regulated 1 | 0.0161174 |
| FNIP1 | folliculin interacting protein 1 | 0.0154598 |
| SETD5 | SET domain containing 5 | 0.015003 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0146944 |
| YEATS2 | YEATS domain containing 2 | 0.0141395 |
| POM121C | POM121 transmembrane nucleoporin C | 0.0138232 |
| ADNP | activity-dependent neuroprotector homeobox | 0.0135492 |
| ITGB4 | integrin, beta 4 | 0.0134912 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0131558 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0127901 |
| AMBRA1 | autophagy/beclin-1 regulator 1 | 0.0127827 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0127252 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0125954 |
| CTTN | cortactin | 0.0124306 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.012252 |
| RPL6 | ribosomal protein L6 | 0.0115476 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0113448 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0113337 |
| EFNA5 | ephrin-A5 | 0.0112665 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0112303 |
| EPB41 | erythrocyte membrane protein band 4.1 | 0.0109607 |
| PLIN3 | perilipin 3 | 0.0108502 |
| PYGB | phosphorylase, glycogen; brain | 0.0106093 |
| BEGAIN | brain-enriched guanylate kinase-associated | 0.0105891 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0103362 |
| GOLPH3 | golgi phosphoprotein 3 (coat-protein) | 0.0102989 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | 0.0102977 |
| FAM13A | family with sequence similarity 13, member A | 0.0102589 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.00970391 |
| NT5DC3 | 5'-nucleotidase domain containing 3 | 0.00957184 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.00955271 |
| SNX3 | sorting nexin 3 | 0.00949785 |
| RNF145 | ring finger protein 145 | 0.00947573 |
| LGALS3 | lectin, galactoside-binding, soluble, 3 | 0.00942931 |
| SFXN1 | sideroflexin 1 | 0.00941561 |
| DSTN | destrin (actin depolymerizing factor) | 0.00931999 |
| RNF149 | ring finger protein 149 | 0.0092447 |
| MXI1 | MAX interactor 1, dimerization protein | 0.00923552 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.009216 |
| ZFR | zinc finger RNA binding protein | 0.00908148 |
| CDK19 | cyclin-dependent kinase 19 | 0.00899566 |
| TRERF1 | transcriptional regulating factor 1 | 0.00890312 |
| URI1 | URI1, prefoldin-like chaperone | 0.00884256 |
| FAM117B | family with sequence similarity 117, member B | 0.00883295 |
| DIP2A | DIP2 disco-interacting protein 2 homolog A (Drosophila) | 0.00881242 |
| KLC1 | kinesin light chain 1 | 0.00877442 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.00874795 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.00873712 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.00872942 |
| KLF10 | Kruppel-like factor 10 | 0.00867372 |
| CD109 | CD109 molecule | 0.00866333 |
| PHYKPL | 5-phosphohydroxy-L-lysine phospho-lyase | 0.00853324 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.00850165 |
| ATN1 | atrophin 1 | 0.00845047 |
| N4BP1 | NEDD4 binding protein 1 | 0.00842903 |
| NECTIN2 | nectin cell adhesion molecule 2 | 0.00831308 |
| MAPK1 | mitogen-activated protein kinase 1 | 0.00825087 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.00823582 |
| WDR20 | WD repeat domain 20 | 0.0081065 |
| NBPF15 | neuroblastoma breakpoint family, member 15 | 0.00810483 |
| GOLGA4 | golgin A4 | 0.00804344 |
| MBTD1 | mbt domain containing 1 | 0.00801966 |
| GPT2 | glutamic pyruvate transaminase (alanine aminotransferase) 2 | 0.00790616 |
| CFAP96 | cilia and flagella associated protein 96 | 0.00786274 |
| BTF3L4 | basic transcription factor 3-like 4 | 0.00782344 |
| DNAJC7 | DnaJ (Hsp40) homolog, subfamily C, member 7 | 0.00781655 |
| ARID3A | AT rich interactive domain 3A (BRIGHT-like) | 0.0077513 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0077467 |
| PDPR | pyruvate dehydrogenase phosphatase regulatory subunit | 0.00760017 |
| SH3GLB1 | SH3-domain GRB2-like endophilin B1 | 0.00750078 |
| SPPL3 | signal peptide peptidase like 3 | 0.00747971 |
| NPHP3 | nephronophthisis 3 (adolescent) | 0.00747094 |
| RARS2 | arginyl-tRNA synthetase 2, mitochondrial | 0.00746636 |
| SINHCAF | SIN3-HDAC complex associated factor | 0.00745388 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | 0.0074195 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.00741596 |
| NEMF | nuclear export mediator factor | 0.0073774 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.00736549 |
| OTUD5 | OTU deubiquitinase 5 | 0.00724298 |
| PALM | paralemmin | 0.00718614 |
| QRICH1 | glutamine-rich 1 | 0.00716619 |
| SSU72 | SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae) | 0.00715012 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.00714984 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.00702182 |
| VPS26C | VPS26 endosomal protein sorting factor C | 0.00693714 |
| CAMKK1 | calcium/calmodulin-dependent protein kinase kinase 1, alpha | 0.00693536 |
| TMEM263 | transmembrane protein 263 | 0.00691386 |
| DFFA | DNA fragmentation factor, 45kDa, alpha polypeptide | 0.00690978 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.281743 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.183114 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.167178 |
| TMSB10 | thymosin beta 10 | -0.162642 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.141466 |
| UBC | ubiquitin C | -0.139842 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.131273 |
| MT2A | metallothionein 2A | -0.130338 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.120283 |
| DST | dystonin | -0.114838 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0940889 |
| TP63 | tumor protein p63 | -0.0879636 |
| AHNAK | AHNAK nucleoprotein | -0.085894 |
| ENO1 | enolase 1, (alpha) | -0.0856917 |
| LDHA | lactate dehydrogenase A | -0.0856205 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0851382 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0843294 |
| TXNRD1 | thioredoxin reductase 1 | -0.0821723 |
| CD44 | CD44 molecule (Indian blood group) | -0.0782156 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0759666 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0750827 |
| JUN | jun proto-oncogene | -0.0744564 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0729196 |
| RPS27A | ribosomal protein S27a | -0.0680828 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0675639 |
| CANX | calnexin | -0.062895 |
| APP | amyloid beta (A4) precursor protein | -0.0604776 |
| RPL23 | ribosomal protein L23 | -0.0599266 |
| SPAG9 | sperm associated antigen 9 | -0.0588937 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0583716 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0580826 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0575799 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0571027 |
| MT1X | metallothionein 1X | -0.0562884 |
| SET | SET nuclear proto-oncogene | -0.0521148 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0504755 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.046593 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0444358 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0435135 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0409295 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0404943 |
| SDC4 | syndecan 4 | -0.0400575 |
| ARHGAP5 | Rho GTPase activating protein 5 | -0.0399599 |
| PGK1 | phosphoglycerate kinase 1 | -0.0395589 |
| YBX1 | Y box binding protein 1 | -0.0395054 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0394102 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0390138 |
| PCBP2 | poly(rC) binding protein 2 | -0.0388977 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0372706 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0370224 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0370189 |
| POTEF | POTE ankyrin domain family, member F | -0.0363181 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0357822 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0357218 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0355764 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0348712 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0344284 |
| USP34 | ubiquitin specific peptidase 34 | -0.0342561 |
| EMP1 | epithelial membrane protein 1 | -0.0341482 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.034124 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0337849 |
| IPO7 | importin 7 | -0.0333798 |
| PKM | pyruvate kinase, muscle | -0.0333311 |
| HMGB2 | high mobility group box 2 | -0.0333292 |
| VMP1 | vacuole membrane protein 1 | -0.0328396 |
| PDE10A | phosphodiesterase 10A | -0.0324517 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0321922 |
| S100A6 | S100 calcium binding protein A6 | -0.0321868 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0320814 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0320526 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0310922 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0310246 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0309746 |
| SEPTIN7 | septin 7 | -0.030381 |
| DNER | delta/notch-like EGF repeat containing | -0.0298706 |
| RBM39 | RNA binding motif protein 39 | -0.0295117 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0292104 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0286553 |
| SP100 | SP100 nuclear antigen | -0.0284201 |
| TMSB4X | thymosin beta 4, X-linked | -0.028256 |
| MT1E | metallothionein 1E | -0.0280658 |
| VCL | vinculin | -0.0280118 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0278605 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0278448 |
| NEK10 | NIMA-related kinase 10 | -0.0278134 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0276124 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.027501 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0272725 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0272392 |
| CMIP | c-Maf inducing protein | -0.0270461 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0270058 |
| CADM2 | cell adhesion molecule 2 | -0.0267714 |
| RAD51B | RAD51 paralog B | -0.0263099 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0262477 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | -0.0260461 |
| MCL1 | myeloid cell leukemia 1 | -0.0259446 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0257666 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0254575 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0254238 |
| SQSTM1 | sequestosome 1 | -0.02515 |
