| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| STC1 | stanniocalcin 1 | 0.163873 |
| PTMA | prothymosin, alpha | 0.142004 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0920448 |
| KLF6 | Kruppel-like factor 6 | 0.0884393 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0768256 |
| PDE10A | phosphodiesterase 10A | 0.0761537 |
| PRKCSH | protein kinase C substrate 80K-H | 0.069471 |
| N4BP1 | NEDD4 binding protein 1 | 0.0684459 |
| RPS3 | ribosomal protein S3 | 0.0678075 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0650018 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0647751 |
| RPL37A | ribosomal protein L37a | 0.0631479 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0627255 |
| YEATS2 | YEATS domain containing 2 | 0.0625532 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | 0.0599446 |
| STEAP4 | STEAP family member 4 | 0.0574274 |
| NKTR | natural killer cell triggering receptor | 0.0573164 |
| NCKAP1 | NCK-associated protein 1 | 0.0555617 |
| CDK6 | cyclin-dependent kinase 6 | 0.0555509 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0555287 |
| RFX7 | regulatory factor X, 7 | 0.0552288 |
| SYT1 | synaptotagmin I | 0.054993 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0542284 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0537346 |
| GNAS | GNAS complex locus | 0.0537319 |
| TMEM65 | transmembrane protein 65 | 0.0516676 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0512112 |
| RIOK3 | RIO kinase 3 | 0.0504675 |
| PDS5B | PDS5 cohesin associated factor B | 0.0498289 |
| TFG | TRK-fused gene | 0.049795 |
| OXR1 | oxidation resistance 1 | 0.0485679 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0473202 |
| RBM15 | RNA binding motif protein 15 | 0.0462351 |
| IGF2 | insulin-like growth factor 2 | 0.0460398 |
| MEIS2 | Meis homeobox 2 | 0.0458993 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0455046 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.044797 |
| HELZ | helicase with zinc finger | 0.0439231 |
| RPL37 | ribosomal protein L37 | 0.0437125 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0434221 |
| ETNK1 | ethanolamine kinase 1 | 0.0426776 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0425928 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0419797 |
| CEP95 | centrosomal protein 95kDa | 0.0419503 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0417631 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.041675 |
| S100A6 | S100 calcium binding protein A6 | 0.0415882 |
| NEK7 | NIMA-related kinase 7 | 0.041551 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0411634 |
| MTUS1 | microtubule associated tumor suppressor 1 | 0.0405674 |
| RPS23 | ribosomal protein S23 | 0.0403186 |
| YAP1 | Yes-associated protein 1 | 0.0399558 |
| H3-3B | H3.3 histone B | 0.0397414 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0394912 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0394831 |
| PDCD10 | programmed cell death 10 | 0.039183 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | 0.0387879 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0387401 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0381657 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0381116 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0380864 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.037949 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0378662 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0377621 |
| RPS19 | ribosomal protein S19 | 0.0376012 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0375201 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.036999 |
| RPLP1 | ribosomal protein, large, P1 | 0.0369767 |
| NDFIP1 | Nedd4 family interacting protein 1 | 0.0364928 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0363532 |
| TXNIP | thioredoxin interacting protein | 0.0360486 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.035959 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.0356109 |
| CCNL1 | cyclin L1 | 0.0354181 |
| TCF12 | transcription factor 12 | 0.0351882 |
| RACK1 | receptor for activated C kinase 1 | 0.0347725 |
| RAB8B | RAB8B, member RAS oncogene family | 0.034562 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0342122 |
| TPD52 | tumor protein D52 | 0.0340087 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0338358 |
| FTL | ferritin, light polypeptide | 0.0338206 |
| KRT8 | keratin 8, type II | 0.0336516 |
| MCL1 | myeloid cell leukemia 1 | 0.0336348 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.033534 |
| MYO6 | myosin VI | 0.0335323 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.033348 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0331518 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0327563 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0327229 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0325646 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0323378 |
| PDS5A | PDS5 cohesin associated factor A | 0.0323101 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0321502 |
| ATP13A3 | ATPase type 13A3 | 0.0320754 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0314389 |
| TMEM123 | transmembrane protein 123 | 0.031423 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0313971 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0312207 |
| RSF1 | remodeling and spacing factor 1 | 0.0312029 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0311907 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LAMB3 | laminin, beta 3 | -0.119621 |
| MYO1E | myosin IE | -0.108449 |
| SPAG9 | sperm associated antigen 9 | -0.107754 |
| ENO1 | enolase 1, (alpha) | -0.0935275 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0934478 |
| ANXA2 | annexin A2 | -0.0927337 |
| ASPH | aspartate beta-hydroxylase | -0.089809 |
| TJP1 | tight junction protein 1 | -0.0870923 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0850578 |
| TXNRD1 | thioredoxin reductase 1 | -0.0846604 |
| CD44 | CD44 molecule (Indian blood group) | -0.0786768 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0746181 |
| EGR1 | early growth response 1 | -0.0731326 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0654905 |
| LMO7 | LIM domain 7 | -0.06404 |
| KRT17 | keratin 17, type I | -0.0634821 |
| MSN | moesin | -0.0626917 |
| SLTM | SAFB-like, transcription modulator | -0.0625203 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0607054 |
| VIM | vimentin | -0.0572976 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0563655 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0559741 |
| LDHA | lactate dehydrogenase A | -0.0557083 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0539528 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0538966 |
| PARD3 | par-3 family cell polarity regulator | -0.0528777 |
| PKM | pyruvate kinase, muscle | -0.0528681 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0503646 |
| CUX1 | cut-like homeobox 1 | -0.0490969 |
| SMYD3 | SET and MYND domain containing 3 | -0.0464205 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0462156 |
| FMNL2 | formin-like 2 | -0.0459912 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0448154 |
| RIGI | RNA sensor RIG-I | -0.0440756 |
| EGFR | epidermal growth factor receptor | -0.0440118 |
| MXD1 | MAX dimerization protein 1 | -0.043725 |
| TNPO1 | transportin 1 | -0.0415222 |
| COPA | coatomer protein complex, subunit alpha | -0.0414307 |
| SETX | senataxin | -0.0413046 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0411658 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0410949 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0410188 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0407461 |
| AK1 | adenylate kinase 1 | -0.0404252 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0403742 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0400344 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0399847 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0399809 |
| SRP54 | signal recognition particle 54kDa | -0.0398329 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0398308 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0386392 |
| LSAMP | limbic system-associated membrane protein | -0.0386204 |
| QKI | QKI, KH domain containing, RNA binding | -0.0384935 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0379895 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0378954 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0377233 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0375608 |
| NBAS | neuroblastoma amplified sequence | -0.0374119 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0369303 |
| RAB10 | RAB10, member RAS oncogene family | -0.0366107 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0360654 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0358743 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0355909 |
| SBF2 | SET binding factor 2 | -0.0349044 |
| GOLGA4 | golgin A4 | -0.0348863 |
| AFF1 | AF4/FMR2 family, member 1 | -0.0346681 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0342735 |
| SON | SON DNA binding protein | -0.0338665 |
| AHNAK | AHNAK nucleoprotein | -0.0335854 |
| FOXP1 | forkhead box P1 | -0.0334588 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0333824 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0333384 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0333313 |
| DENND4A | DENN/MADD domain containing 4A | -0.0330705 |
| DPYD | dihydropyrimidine dehydrogenase | -0.033046 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0329318 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | -0.0328302 |
| RND3 | Rho family GTPase 3 | -0.0328111 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0323187 |
| SEPTIN9 | septin 9 | -0.0322359 |
| ZXDC | ZXD family zinc finger C | -0.0320386 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0315857 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0312727 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0307476 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0301604 |
| MAST4 | microtubule associated serine/threonine kinase family member 4 | -0.0301071 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0299031 |
| EXOC6B | exocyst complex component 6B | -0.0295601 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0293656 |
| EXOC4 | exocyst complex component 4 | -0.0292671 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0292092 |
| VCL | vinculin | -0.0290905 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.028953 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0289023 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.028754 |
| FRYL | FRY-like | -0.0287136 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0286356 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0283664 |
| POTEF | POTE ankyrin domain family, member F | -0.0275517 |
| MORF4L2 | mortality factor 4 like 2 | -0.0274262 |
