| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ZNF292 | zinc finger protein 292 | 0.0742373 |
| PTMA | prothymosin, alpha | 0.0680556 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0611141 |
| USP3 | ubiquitin specific peptidase 3 | 0.0547772 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0533924 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | 0.0522932 |
| H1-4 | H1.4 linker histone, cluster member | 0.0493704 |
| SPAG9 | sperm associated antigen 9 | 0.0445718 |
| WDR43 | WD repeat domain 43 | 0.0434544 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0421928 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0407539 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0397301 |
| CDC73 | cell division cycle 73 | 0.038577 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0335277 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0334055 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0322836 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0307101 |
| THBS1 | thrombospondin 1 | 0.0299155 |
| CCNL1 | cyclin L1 | 0.0299012 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0289317 |
| ACTG1 | actin gamma 1 | 0.0289175 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0286766 |
| SRPK2 | SRSF protein kinase 2 | 0.0284476 |
| NCKAP1 | NCK-associated protein 1 | 0.0276036 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0268886 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0267672 |
| LHFPL6 | LHFPL tetraspan subfamily member 6 | 0.0261834 |
| TPM3 | tropomyosin 3 | 0.0258997 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0258553 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0257036 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0251264 |
| XPR1 | xenotropic and polytropic retrovirus receptor 1 | 0.024527 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0244169 |
| TCEA1 | transcription elongation factor A (SII), 1 | 0.0241974 |
| TRPS1 | trichorhinophalangeal syndrome I | 0.0241113 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0240965 |
| PDS5B | PDS5 cohesin associated factor B | 0.0238446 |
| RHEB | Ras homolog enriched in brain | 0.0236596 |
| MRPS30 | mitochondrial ribosomal protein S30 | 0.0235798 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | 0.0234983 |
| TMSB4X | thymosin beta 4, X-linked | 0.0233891 |
| CNOT4 | CCR4-NOT transcription complex, subunit 4 | 0.0233787 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0228445 |
| FIGN | fidgetin | 0.0221585 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0221424 |
| STRN | striatin, calmodulin binding protein | 0.0221081 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0218981 |
| CORO1C | coronin, actin binding protein, 1C | 0.0218963 |
| DMXL1 | Dmx-like 1 | 0.0218425 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0217271 |
| ZNF451 | zinc finger protein 451 | 0.0215769 |
| PLEKHF2 | pleckstrin homology domain containing, family F (with FYVE domain) member 2 | 0.0215039 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.021445 |
| H1-2 | H1.2 linker histone, cluster member | 0.0214336 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0211799 |
| SMG7 | SMG7 nonsense mediated mRNA decay factor | 0.0211016 |
| CENPE | centromere protein E, 312kDa | 0.0209709 |
| BNC2 | basonuclin 2 | 0.0208376 |
| OSBPL9 | oxysterol binding protein-like 9 | 0.0207747 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0204616 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0204231 |
| PRKAA1 | protein kinase, AMP-activated, alpha 1 catalytic subunit | 0.0201248 |
| DNMBP | dynamin binding protein | 0.0200906 |
| USP25 | ubiquitin specific peptidase 25 | 0.0198335 |
| SMAP1 | small ArfGAP 1 | 0.0197062 |
| MB21D2 | Mab-21 domain containing 2 | 0.019533 |
| FAM168A | family with sequence similarity 168, member A | 0.0195234 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.019522 |
| SLMAP | sarcolemma associated protein | 0.0195215 |
| WDR75 | WD repeat domain 75 | 0.0191018 |
| SOX5 | SRY (sex determining region Y)-box 5 | 0.019078 |
| CENPC | centromere protein C | 0.018994 |
| BAG4 | BCL2-associated athanogene 4 | 0.018965 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | 0.0188465 |
| FCHSD2 | FCH and double SH3 domains 2 | 0.0187174 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.018701 |
| MEMO1 | mediator of cell motility 1 | 0.0186626 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0185229 |
| KIF5B | kinesin family member 5B | 0.0184587 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0184185 |
| TRAK1 | trafficking protein, kinesin binding 1 | 0.0182267 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0179741 |
| DENND4A | DENN/MADD domain containing 4A | 0.0179435 |
| USP24 | ubiquitin specific peptidase 24 | 0.0178842 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.017819 |
| ADAR | adenosine deaminase, RNA-specific | 0.017678 |
| NARS1 | asparaginyl-tRNA synthetase 1 | 0.0174993 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0174773 |
| SUCO | SUN domain containing ossification factor | 0.0174599 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0173762 |
| OTUD6B | OTU domain containing 6B | 0.0173431 |
| CPA6 | carboxypeptidase A6 | 0.0171259 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.017109 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0169123 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0168744 |
| ECT2 | epithelial cell transforming 2 | 0.016832 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0167114 |
| ABI1 | abl-interactor 1 | 0.0166685 |
| CDC37 | cell division cycle 37 | 0.0165524 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0165228 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.11671 |
| COL11A1 | collagen, type XI, alpha 1 | -0.105854 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0950015 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | -0.070724 |
| TMSB10 | thymosin beta 10 | -0.0681385 |
| RPS6 | ribosomal protein S6 | -0.0653519 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.065201 |
| RPLP1 | ribosomal protein, large, P1 | -0.0624165 |
| RPL23 | ribosomal protein L23 | -0.0608464 |
| RPL35A | ribosomal protein L35a | -0.0590334 |
| PHIP | pleckstrin homology domain interacting protein | -0.0588667 |
| CADM2 | cell adhesion molecule 2 | -0.0573759 |
| RPS8 | ribosomal protein S8 | -0.0571195 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.056394 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0520197 |
| MEIS2 | Meis homeobox 2 | -0.0503564 |
| RPLP0 | ribosomal protein, large, P0 | -0.0487077 |
| YBX1 | Y box binding protein 1 | -0.0470131 |
| PRELID2 | PRELI domain containing 2 | -0.0467158 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0463103 |
| NTM | neurotrimin | -0.0460398 |
| RPS16 | ribosomal protein S16 | -0.0459595 |
| LPIN2 | lipin 2 | -0.0454401 |
| PGK1 | phosphoglycerate kinase 1 | -0.0453213 |
| VIM | vimentin | -0.0439742 |
| PEG10 | paternally expressed 10 | -0.0435034 |
| LDHA | lactate dehydrogenase A | -0.0428097 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0425414 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0421705 |
| POTEF | POTE ankyrin domain family, member F | -0.0419003 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0409557 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0408657 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0401741 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.040023 |
| RAD51B | RAD51 paralog B | -0.0394951 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | -0.0390232 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0382205 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0380308 |
| PFN1 | profilin 1 | -0.03755 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0368153 |
| RPS4X | ribosomal protein S4, X-linked | -0.0363839 |
| CDH19 | cadherin 19, type 2 | -0.0362516 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0359347 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0357735 |
| SNX6 | sorting nexin 6 | -0.0356688 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | -0.0351276 |
| COL1A2 | collagen, type I, alpha 2 | -0.0350785 |
| SEPTIN7 | septin 7 | -0.0350002 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0348336 |
| TBL1X | transducin (beta)-like 1X-linked | -0.0344607 |
| PCLO | piccolo presynaptic cytomatrix protein | -0.0341577 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0337272 |
| ENO1 | enolase 1, (alpha) | -0.0337024 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.0334149 |
| RPS19 | ribosomal protein S19 | -0.0334129 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0331675 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0331564 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | -0.0331159 |
| TUBA1B | tubulin, alpha 1b | -0.0330694 |
| MED12L | mediator complex subunit 12-like | -0.0324271 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0322541 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | -0.0322345 |
| CALR | calreticulin | -0.0305737 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0303151 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0300835 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0299793 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0297352 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0296547 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0296444 |
| ATXN2 | ataxin 2 | -0.0291606 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0290197 |
| AHNAK | AHNAK nucleoprotein | -0.0288248 |
| HMGB2 | high mobility group box 2 | -0.0287708 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0287553 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.028737 |
| GARRE1 | granule associated Rac and RHOG effector 1 | -0.0284663 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0283496 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.028228 |
| FAT1 | FAT atypical cadherin 1 | -0.0281254 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.0279447 |
| FBXO17 | F-box protein 17 | -0.0278315 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0278305 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0277898 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0277532 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0276983 |
| TENM3 | teneurin transmembrane protein 3 | -0.0275519 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.0270451 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0269761 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0264096 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0263692 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0260922 |
| NBEAL1 | neurobeachin-like 1 | -0.0259166 |
| FAM177A1 | family with sequence similarity 177, member A1 | -0.0257519 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0256709 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0256351 |
| CAVIN1 | caveolae associated protein 1 | -0.0255323 |
| HMGB1 | high mobility group box 1 | -0.0255235 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0253639 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0251526 |
| RPS14 | ribosomal protein S14 | -0.0251012 |
