| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in PANC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_PANC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.159857 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.14634 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0849924 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0840942 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0750224 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0718931 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0718345 |
| ASPH | aspartate beta-hydroxylase | 0.0674367 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0623727 |
| ZNF292 | zinc finger protein 292 | 0.0623164 |
| MT2A | metallothionein 2A | 0.0594043 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.056813 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0567087 |
| RPS12 | ribosomal protein S12 | 0.0566504 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0540421 |
| PRELID2 | PRELI domain containing 2 | 0.0520902 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0517664 |
| RPS2 | ribosomal protein S2 | 0.0490161 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0486741 |
| SNX14 | sorting nexin 14 | 0.0468204 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0459525 |
| SMAD3 | SMAD family member 3 | 0.0455754 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0440386 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0432215 |
| SET | SET nuclear proto-oncogene | 0.0430552 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0428783 |
| RPLP1 | ribosomal protein, large, P1 | 0.0424732 |
| ANXA2 | annexin A2 | 0.0419487 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0413914 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0396005 |
| ARRDC3 | arrestin domain containing 3 | 0.0389548 |
| OGA | O-GlcNAcase | 0.03804 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0370155 |
| JMJD1C | jumonji domain containing 1C | 0.0356283 |
| MATR3 | matrin 3 | 0.0351662 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0349321 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0347295 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0346442 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0342825 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0340408 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0328516 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0326684 |
| RPL4 | ribosomal protein L4 | 0.032365 |
| SMYD3 | SET and MYND domain containing 3 | 0.0317364 |
| SQSTM1 | sequestosome 1 | 0.0315538 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0314752 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0310802 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0310212 |
| TXNRD1 | thioredoxin reductase 1 | 0.0308679 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0307389 |
| RPLP2 | ribosomal protein, large, P2 | 0.0302997 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0301895 |
| CDK19 | cyclin-dependent kinase 19 | 0.0301078 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0299017 |
| RPS17 | ribosomal protein S17 | 0.0297483 |
| PDE3B | phosphodiesterase 3B, cGMP-inhibited | 0.0296948 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0295311 |
| IPO7 | importin 7 | 0.0288944 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0288537 |
| AHNAK | AHNAK nucleoprotein | 0.0287163 |
| ENO1 | enolase 1, (alpha) | 0.0286324 |
| SERINC1 | serine incorporator 1 | 0.0277379 |
| ZFP36 | ZFP36 ring finger protein | 0.0277058 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0272839 |
| RPS8 | ribosomal protein S8 | 0.0269919 |
| IL13RA1 | interleukin 13 receptor, alpha 1 | 0.0268873 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0265719 |
| YAP1 | Yes-associated protein 1 | 0.0264924 |
| RPL37A | ribosomal protein L37a | 0.0262251 |
| RPL12 | ribosomal protein L12 | 0.0260351 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0260313 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0260142 |
| MYBL1 | v-myb avian myeloblastosis viral oncogene homolog-like 1 | 0.0259931 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0258905 |
| GCNT2 | glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group) | 0.0258241 |
| RPS3 | ribosomal protein S3 | 0.0258079 |
| NFIA | nuclear factor I/A | 0.0254642 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0254319 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0250444 |
| DHX32 | DEAH (Asp-Glu-Ala-His) box polypeptide 32 | 0.0249161 |
| RPL26 | ribosomal protein L26 | 0.0248924 |
| MYOF | myoferlin | 0.0245412 |
| RNF145 | ring finger protein 145 | 0.0243896 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.024072 |
| AFAP1 | actin filament associated protein 1 | 0.0239691 |
| GRK5 | G protein-coupled receptor kinase 5 | 0.0239384 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0238338 |
| MED13L | mediator complex subunit 13-like | 0.0237041 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0236722 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0228301 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0226922 |
| ATXN1 | ataxin 1 | 0.0224866 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0221491 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0212397 |
| DNMBP | dynamin binding protein | 0.0211467 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.021131 |
| EFNA5 | ephrin-A5 | 0.0209172 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.020854 |
| WWOX | WW domain containing oxidoreductase | 0.0207358 |
| CD44 | CD44 molecule (Indian blood group) | 0.0205983 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.135912 |
| FBL | fibrillarin | -0.116886 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.101362 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0754176 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0709482 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0697913 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0615354 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0607732 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0584588 |
| EGR1 | early growth response 1 | -0.0582207 |
| EGFR | epidermal growth factor receptor | -0.0575716 |
| CTSD | cathepsin D | -0.0575624 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0575329 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0538017 |
| VIM | vimentin | -0.0514156 |
| AKT2 | v-akt murine thymoma viral oncogene homolog 2 | -0.0489463 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0476249 |
| MAP1B | microtubule-associated protein 1B | -0.0464377 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0463515 |
| VCL | vinculin | -0.0457776 |
| PSMC4 | proteasome (prosome, macropain) 26S subunit, ATPase, 4 | -0.0437726 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0435414 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0391024 |
| CALR | calreticulin | -0.0385795 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | -0.0373366 |
| UBAP2 | ubiquitin associated protein 2 | -0.0362435 |
| HMGA1 | high mobility group AT-hook 1 | -0.0351083 |
| CANX | calnexin | -0.032703 |
| WASF2 | WAS protein family, member 2 | -0.0302751 |
| RASAL2 | RAS protein activator like 2 | -0.0296549 |
| L1CAM | L1 cell adhesion molecule | -0.0296062 |
| INTS6 | integrator complex subunit 6 | -0.0287334 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0282778 |
| RPS16 | ribosomal protein S16 | -0.0281978 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0277431 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0272362 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | -0.0268259 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0267755 |
| ATG7 | autophagy related 7 | -0.0265197 |
| UBC | ubiquitin C | -0.0263102 |
| VEGFA | vascular endothelial growth factor A | -0.0251751 |
| TAPBP | TAP binding protein (tapasin) | -0.0249909 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0245807 |
| SRRM2 | serine/arginine repetitive matrix 2 | -0.0240547 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0240354 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0237803 |
| COPA | coatomer protein complex, subunit alpha | -0.0236668 |
| ARF4 | ADP-ribosylation factor 4 | -0.0235621 |
| PFN1 | profilin 1 | -0.0233937 |
| NUP98 | nucleoporin 98kDa | -0.0233112 |
| MYO1E | myosin IE | -0.0229634 |
| HM13 | histocompatibility (minor) 13 | -0.0228023 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0225934 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0224542 |
| TMSB10 | thymosin beta 10 | -0.0222543 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0221583 |
| HDLBP | high density lipoprotein binding protein | -0.0220831 |
| FTL | ferritin, light polypeptide | -0.0219429 |
| BRD2 | bromodomain containing 2 | -0.0218534 |
| MYADM | myeloid-associated differentiation marker | -0.0217959 |
| EHBP1 | EH domain binding protein 1 | -0.0217049 |
| TPM1 | tropomyosin 1 (alpha) | -0.0216047 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0212336 |
| ASNS | asparagine synthetase (glutamine-hydrolyzing) | -0.0204596 |
| FLNA | filamin A, alpha | -0.0204258 |
| FBXO17 | F-box protein 17 | -0.0202895 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0201311 |
| DST | dystonin | -0.0199317 |
| ACTG1 | actin gamma 1 | -0.0198794 |
| ADM | adrenomedullin | -0.0197303 |
| CALU | calumenin | -0.0196088 |
| GOLGA3 | golgin A3 | -0.0194512 |
| HLA-B | major histocompatibility complex, class I, B | -0.019442 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.019428 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0190993 |
| RSU1 | Ras suppressor protein 1 | -0.0185924 |
| SAMD4B | sterile alpha motif domain containing 4B | -0.0185074 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0183758 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.018321 |
| MAP4 | microtubule-associated protein 4 | -0.0181352 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0179153 |
| JUN | jun proto-oncogene | -0.0178411 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0177818 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0177481 |
| LDHA | lactate dehydrogenase A | -0.0177047 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0176275 |
| UPP1 | uridine phosphorylase 1 | -0.0175946 |
| MAGT1 | magnesium transporter 1 | -0.0173427 |
| SEC23IP | SEC23 interacting protein | -0.0170931 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0169102 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | -0.0168127 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0166965 |
| RBMX | RNA binding motif protein, X-linked | -0.016686 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0166762 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0166654 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0164517 |
| WDR27 | WD repeat domain 27 | -0.0163964 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0162936 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.016216 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0161909 |
