| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in Panc 03.27 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_Panc 03.27 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.123994 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.106294 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0725204 |
| B2M | beta-2-microglobulin | 0.0702932 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.067866 |
| TGM2 | transglutaminase 2 | 0.0624116 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0547536 |
| RPS3 | ribosomal protein S3 | 0.0529097 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0502026 |
| NDRG1 | N-myc downstream regulated 1 | 0.0501753 |
| TMF1 | TATA element modulatory factor 1 | 0.0490136 |
| FMNL2 | formin-like 2 | 0.0473971 |
| SETD5 | SET domain containing 5 | 0.0471683 |
| RPS12 | ribosomal protein S12 | 0.0458044 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0445766 |
| RPS6 | ribosomal protein S6 | 0.041817 |
| POTEF | POTE ankyrin domain family, member F | 0.0408167 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0397898 |
| DSG2 | desmoglein 2 | 0.0396431 |
| BRD4 | bromodomain containing 4 | 0.0385531 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0380864 |
| G0S2 | G0/G1 switch 2 | 0.0378505 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0370381 |
| BBX | bobby sox homolog (Drosophila) | 0.0362291 |
| GOLGA4 | golgin A4 | 0.0356217 |
| MYO6 | myosin VI | 0.0350671 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0345865 |
| HLA-A | major histocompatibility complex, class I, A | 0.03422 |
| FNIP1 | folliculin interacting protein 1 | 0.0340786 |
| TXNIP | thioredoxin interacting protein | 0.0335695 |
| LAMB3 | laminin, beta 3 | 0.0331757 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0328531 |
| FOSL1 | FOS-like antigen 1 | 0.0320437 |
| NCKAP1 | NCK-associated protein 1 | 0.031938 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0311094 |
| C3 | complement component 3 | 0.0310668 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0310508 |
| ARRDC3 | arrestin domain containing 3 | 0.0302164 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0301955 |
| FGD4 | FYVE, RhoGEF and PH domain containing 4 | 0.0298048 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0296106 |
| CTTN | cortactin | 0.0289143 |
| MUC16 | mucin 16, cell surface associated | 0.0287967 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0287825 |
| FAM13A | family with sequence similarity 13, member A | 0.0286613 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0286582 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0284524 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0283369 |
| RPS8 | ribosomal protein S8 | 0.0281978 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.027712 |
| PDE8A | phosphodiesterase 8A | 0.0276724 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0275728 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0271072 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0269828 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0266088 |
| YAP1 | Yes-associated protein 1 | 0.0265181 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0263976 |
| CCNY | cyclin Y | 0.0259759 |
| RACK1 | receptor for activated C kinase 1 | 0.0258784 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0258773 |
| H1-4 | H1.4 linker histone, cluster member | 0.0254655 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0253932 |
| RPS29 | ribosomal protein S29 | 0.025352 |
| RPS2 | ribosomal protein S2 | 0.024957 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0249081 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0248792 |
| TPM3 | tropomyosin 3 | 0.0246591 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0246556 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0244388 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0244311 |
| CCNL1 | cyclin L1 | 0.0243891 |
| HDGF | hepatoma-derived growth factor | 0.0241963 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0239938 |
| RPL21 | ribosomal protein L21 | 0.023656 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0235739 |
| CD44 | CD44 molecule (Indian blood group) | 0.0232054 |
| ACTG1 | actin gamma 1 | 0.0228645 |
| AXL | AXL receptor tyrosine kinase | 0.0228644 |
| RDX | radixin | 0.0226752 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0223677 |
| DSTN | destrin (actin depolymerizing factor) | 0.0220944 |
| CREBRF | CREB3 regulatory factor | 0.0220721 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0219421 |
| CD47 | CD47 molecule | 0.0215351 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | 0.0213865 |
| H2AC6 | H2A clustered histone 6 | 0.0212055 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0209362 |
| MXI1 | MAX interactor 1, dimerization protein | 0.020876 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.020833 |
| RPL3 | ribosomal protein L3 | 0.0206145 |
| RPL18 | ribosomal protein L18 | 0.0205772 |
| RPL36 | ribosomal protein L36 | 0.0203848 |
| CMTM6 | CKLF-like MARVEL transmembrane domain containing 6 | 0.0203239 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | 0.0200344 |
| SRI | sorcin | 0.0200061 |
| OXR1 | oxidation resistance 1 | 0.0199651 |
| SEPTIN9 | septin 9 | 0.0197973 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.0197726 |
| PNN | pinin, desmosome associated protein | 0.0197481 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | 0.0196742 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.137625 |
| LOC112694756 | uncharaterized LOC112694756 | -0.103253 |
| LDHA | lactate dehydrogenase A | -0.0989229 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0936878 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.090101 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0814511 |
| TMSB4X | thymosin beta 4, X-linked | -0.0765527 |
| RPL35A | ribosomal protein L35a | -0.0746979 |
| EGR1 | early growth response 1 | -0.0746661 |
| RBM39 | RNA binding motif protein 39 | -0.073277 |
| TMSB10 | thymosin beta 10 | -0.0726144 |
| MUC4 | mucin 4, cell surface associated | -0.0693234 |
| KRT19 | keratin 19, type I | -0.0639737 |
| HMGA1 | high mobility group AT-hook 1 | -0.0635556 |
| CANX | calnexin | -0.0631551 |
| LAMA4 | laminin, alpha 4 | -0.0609269 |
| TJP1 | tight junction protein 1 | -0.0604345 |
| EZR | ezrin | -0.0588651 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0530545 |
| SPAG9 | sperm associated antigen 9 | -0.0528272 |
| EFNA5 | ephrin-A5 | -0.0519081 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0507634 |
| AHNAK | AHNAK nucleoprotein | -0.0494887 |
| OSMR | oncostatin M receptor | -0.0492021 |
| RUNX1 | runt-related transcription factor 1 | -0.0475604 |
| PLSCR1 | phospholipid scramblase 1 | -0.0468795 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | -0.0455718 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0439285 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0436424 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.042762 |
| LMO7 | LIM domain 7 | -0.0425898 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.042402 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0423872 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0410713 |
| RPS24 | ribosomal protein S24 | -0.0405321 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0402627 |
| SMC4 | structural maintenance of chromosomes 4 | -0.040089 |
| TXNRD1 | thioredoxin reductase 1 | -0.0399325 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0393988 |
| HLA-C | major histocompatibility complex, class I, C | -0.0389367 |
| RPL23 | ribosomal protein L23 | -0.038863 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0383596 |
| ARF1 | ADP-ribosylation factor 1 | -0.038336 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0380633 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0376707 |
| SDC4 | syndecan 4 | -0.0366099 |
| MORF4L2 | mortality factor 4 like 2 | -0.0351163 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0350613 |
| ACTN4 | actinin, alpha 4 | -0.0348965 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0338888 |
| VCL | vinculin | -0.0336794 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0331544 |
| HMGB2 | high mobility group box 2 | -0.0329644 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0321483 |
| YBX1 | Y box binding protein 1 | -0.0318542 |
| RPLP1 | ribosomal protein, large, P1 | -0.0318414 |
| TAPBP | TAP binding protein (tapasin) | -0.0314126 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0313863 |
| NPC1 | Niemann-Pick disease, type C1 | -0.0310545 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.030889 |
| RNF213 | ring finger protein 213 | -0.0305342 |
| USP9X | ubiquitin specific peptidase 9, X-linked | -0.0301874 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0296022 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0294396 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0294247 |
| SRSF3 | serine/arginine-rich splicing factor 3 | -0.0290653 |
| HDLBP | high density lipoprotein binding protein | -0.0289016 |
| ECT2 | epithelial cell transforming 2 | -0.0286402 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0285982 |
| S100A6 | S100 calcium binding protein A6 | -0.028434 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0284287 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0278428 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.0276163 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0275682 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0275612 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0273729 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0267338 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.026647 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0266123 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0264947 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.026485 |
| IER3 | immediate early response 3 | -0.0262488 |
| DIAPH3 | diaphanous-related formin 3 | -0.0260311 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0259787 |
| WWC1 | WW and C2 domain containing 1 | -0.0258523 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.025637 |
| THBS1 | thrombospondin 1 | -0.0255088 |
| BMAL2 | basic helix-loop-helix ARNT like 2 | -0.0253366 |
| KRT7 | keratin 7, type II | -0.025297 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0251943 |
| CEP95 | centrosomal protein 95kDa | -0.0248584 |
| RPS20 | ribosomal protein S20 | -0.0246384 |
| KRT8 | keratin 8, type II | -0.0244668 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0240362 |
| RTN3 | reticulon 3 | -0.0237972 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.023688 |
| TFRC | transferrin receptor | -0.023683 |
| DST | dystonin | -0.023406 |
| LATS2 | large tumor suppressor kinase 2 | -0.0232846 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0232668 |
