| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in SK-MEL-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_SK-MEL-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.031588 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0288693 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.027176 |
| FAM13A | family with sequence similarity 13, member A | 0.0266237 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | 0.0256169 |
| FNDC3B | fibronectin type III domain containing 3B | 0.025375 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0250343 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0250192 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0242309 |
| HPCAL1 | hippocalcin-like 1 | 0.0242052 |
| NGLY1 | N-glycanase 1 | 0.023869 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.0226572 |
| NBPF15 | neuroblastoma breakpoint family, member 15 | 0.0223911 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0223488 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0222857 |
| GPR137B | G protein-coupled receptor 137B | 0.0221525 |
| CLIP4 | CAP-GLY domain containing linker protein family, member 4 | 0.0213702 |
| HELZ | helicase with zinc finger | 0.0212255 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | 0.0211847 |
| H1-4 | H1.4 linker histone, cluster member | 0.0202154 |
| SETD5 | SET domain containing 5 | 0.019717 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0190484 |
| MSI2 | musashi RNA-binding protein 2 | 0.0185111 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0184854 |
| FOSL1 | FOS-like antigen 1 | 0.0177622 |
| CTTN | cortactin | 0.0175192 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0163651 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0163257 |
| USP3 | ubiquitin specific peptidase 3 | 0.0158631 |
| CCNL1 | cyclin L1 | 0.0158538 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0157697 |
| PLAUR | plasminogen activator, urokinase receptor | 0.01488 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0147169 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0145165 |
| POM121 | POM121 transmembrane nucleoporin | 0.0144594 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0143894 |
| CLEC2D | C-type lectin domain family 2, member D | 0.0143883 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0143294 |
| ZNRF1 | zinc and ring finger 1, E3 ubiquitin protein ligase | 0.0142117 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.0139678 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0137498 |
| KAZN | kazrin, periplakin interacting protein | 0.0137346 |
| TPD52 | tumor protein D52 | 0.0136495 |
| ZNF292 | zinc finger protein 292 | 0.0136232 |
| RTN4 | reticulon 4 | 0.0133694 |
| C1GALT1 | core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 | 0.013335 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0129277 |
| SEC24A | SEC24 family member A | 0.0129229 |
| ATF4 | activating transcription factor 4 | 0.0128906 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0127319 |
| CDK19 | cyclin-dependent kinase 19 | 0.0127116 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.0126897 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0125585 |
| FMNL2 | formin-like 2 | 0.0123866 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0123103 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.01231 |
| TMEM41B | transmembrane protein 41B | 0.0123091 |
| KIF5C | kinesin family member 5C | 0.0122355 |
| SNAPC3 | small nuclear RNA activating complex, polypeptide 3, 50kDa | 0.0121663 |
| NBPF8 | neuroblastoma breakpoint family, member 8 | 0.0121415 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0121305 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0120397 |
| SRP54 | signal recognition particle 54kDa | 0.0120184 |
| TMEM39A | transmembrane protein 39A | 0.0115869 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0115724 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0114552 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0114317 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0114216 |
| LNPK | lunapark, ER junction formation factor | 0.0113578 |
| RNF24 | ring finger protein 24 | 0.0110291 |
| SNU13 | small nuclear ribonucleoprotein 13 | 0.0109715 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0108989 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0108694 |
| ZBTB43 | zinc finger and BTB domain containing 43 | 0.0108454 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0108084 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0108059 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0108056 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0107606 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | 0.0106162 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0105226 |
| C1ORF52 | chromosome 1 open reading frame 52 | 0.0104635 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0103902 |
| SBF2 | SET binding factor 2 | 0.0103667 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | 0.0103418 |
| BCAP31 | B-cell receptor-associated protein 31 | 0.0101552 |
| THOC2 | THO complex 2 | 0.0101542 |
| ATXN3 | ataxin 3 | 0.0101434 |
| KIAA1958 | KIAA1958 | 0.0101023 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | 0.0100851 |
| NDRG1 | N-myc downstream regulated 1 | 0.0100534 |
| MXRA7 | matrix-remodelling associated 7 | 0.00996461 |
| MSN | moesin | 0.00995685 |
| TRAM1 | translocation associated membrane protein 1 | 0.00993831 |
| CABIN1 | calcineurin binding protein 1 | 0.00988646 |
| FBXL4 | F-box and leucine-rich repeat protein 4 | 0.00974762 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.00973075 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.00971407 |
| PRR13 | proline rich 13 | 0.00968357 |
| CALD1 | caldesmon 1 | 0.00966246 |
| WASF2 | WAS protein family, member 2 | 0.00959787 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.244699 |
| FMN1 | formin 1 | -0.186763 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.173166 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.14451 |
| NLGN1 | neuroligin 1 | -0.134229 |
| UBC | ubiquitin C | -0.125495 |
| FN1 | fibronectin 1 | -0.11615 |
| ENO1 | enolase 1, (alpha) | -0.112106 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0934021 |
| NRG3 | neuregulin 3 | -0.0917736 |
| LSAMP | limbic system-associated membrane protein | -0.0895839 |
| PKM | pyruvate kinase, muscle | -0.0890852 |
| TMSB10 | thymosin beta 10 | -0.0889936 |
| CCND1 | cyclin D1 | -0.0818684 |
| LDHA | lactate dehydrogenase A | -0.0811837 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0776272 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0768131 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0698114 |
| ANKRD1 | ankyrin repeat domain 1 (cardiac muscle) | -0.0664693 |
| DST | dystonin | -0.0663263 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0658487 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0637757 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.061672 |
| RPL23 | ribosomal protein L23 | -0.0615112 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0590376 |
| FRMD4A | FERM domain containing 4A | -0.0590277 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0581067 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0561779 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0555836 |
| RPS27A | ribosomal protein S27a | -0.0547955 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0524059 |
| SQSTM1 | sequestosome 1 | -0.0520723 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0508968 |
| CANX | calnexin | -0.0495281 |
| TXNRD1 | thioredoxin reductase 1 | -0.0492641 |
| AHNAK | AHNAK nucleoprotein | -0.049038 |
| PGK1 | phosphoglycerate kinase 1 | -0.0481478 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0458103 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0436101 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0435095 |
| HDAC9 | histone deacetylase 9 | -0.0433066 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0432375 |
| PCBP2 | poly(rC) binding protein 2 | -0.042502 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0412526 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.041156 |
| RNF213 | ring finger protein 213 | -0.041043 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0405511 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0401757 |
| RAD51B | RAD51 paralog B | -0.0401369 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0400951 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.039917 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | -0.0397636 |
| POTEF | POTE ankyrin domain family, member F | -0.0391829 |
| COMMD10 | COMM domain containing 10 | -0.0387623 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0381132 |
| SP100 | SP100 nuclear antigen | -0.038111 |
| EMP1 | epithelial membrane protein 1 | -0.0376318 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0371944 |
| ST13 | suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein) | -0.0367197 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0365782 |
| RUNX1 | runt-related transcription factor 1 | -0.0362843 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0357767 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0353505 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0351616 |
| RASAL2 | RAS protein activator like 2 | -0.0344537 |
| TNNC1 | troponin C type 1 (slow) | -0.0331757 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0329316 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0326853 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0326485 |
| ACTN4 | actinin, alpha 4 | -0.0317052 |
| SET | SET nuclear proto-oncogene | -0.0315944 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0314606 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0312717 |
| XRCC6 | X-ray repair complementing defective repair in Chinese hamster cells 6 | -0.0312275 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | -0.0310738 |
| IPO7 | importin 7 | -0.0307039 |
| APOD | apolipoprotein D | -0.0302439 |
| RPS3 | ribosomal protein S3 | -0.030214 |
| ASPH | aspartate beta-hydroxylase | -0.0301683 |
| FHIT | fragile histidine triad | -0.0301252 |
| SEPTIN7 | septin 7 | -0.0299308 |
| SFPQ | splicing factor proline/glutamine-rich | -0.0298948 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0297877 |
| BPTF | bromodomain PHD finger transcription factor | -0.0297006 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0291024 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0289923 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0289632 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0286432 |
| LINC02798 | long intergenic non-protein coding RNA 2798 | -0.0285863 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0285785 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0285282 |
| HMGB2 | high mobility group box 2 | -0.0284927 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0281379 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0280072 |
| ERBIN | erbb2 interacting protein | -0.0278888 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0278081 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0274234 |
| FRMD5 | FERM domain containing 5 | -0.0273943 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.027364 |
| CDK13 | cyclin-dependent kinase 13 | -0.027131 |
