| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.134352 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.102238 |
| PDE10A | phosphodiesterase 10A | 0.0834214 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.080644 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0702088 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0675828 |
| HDAC9 | histone deacetylase 9 | 0.066268 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0557528 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0555256 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0529609 |
| VCAN | versican | 0.0457434 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0447403 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0445648 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0426705 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0423444 |
| RPS2 | ribosomal protein S2 | 0.0395996 |
| GPC6 | glypican 6 | 0.0379638 |
| RAD51B | RAD51 paralog B | 0.0375112 |
| HMGA2 | high mobility group AT-hook 2 | 0.0373708 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0373572 |
| SMYD3 | SET and MYND domain containing 3 | 0.0368657 |
| CDK19 | cyclin-dependent kinase 19 | 0.036736 |
| PRELID2 | PRELI domain containing 2 | 0.0366743 |
| RPS12 | ribosomal protein S12 | 0.0362625 |
| VIM | vimentin | 0.0349381 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0347469 |
| FNIP1 | folliculin interacting protein 1 | 0.0346191 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.034334 |
| ENO1 | enolase 1, (alpha) | 0.032695 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0323118 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0322442 |
| FRMD4A | FERM domain containing 4A | 0.0320091 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0308334 |
| FLOT1 | flotillin 1 | 0.0306667 |
| ATXN1 | ataxin 1 | 0.0304538 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0286099 |
| TNS3 | tensin 3 | 0.0284299 |
| DIAPH2 | diaphanous-related formin 2 | 0.0281835 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0281356 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.027796 |
| SET | SET nuclear proto-oncogene | 0.0275765 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0273734 |
| MYOF | myoferlin | 0.0270286 |
| ARFGEF3 | ARFGEF family member 3 | 0.0269813 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0264202 |
| CDH13 | cadherin 13 | 0.0263345 |
| DST | dystonin | 0.0263249 |
| FAM20C | family with sequence similarity 20, member C | 0.0262744 |
| KYNU | kynureninase | 0.0256891 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0250958 |
| ASPH | aspartate beta-hydroxylase | 0.0250362 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | 0.0247528 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0242076 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0241743 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0241367 |
| ATM | ATM serine/threonine kinase | 0.0233835 |
| RND3 | Rho family GTPase 3 | 0.0233776 |
| PLIN2 | perilipin 2 | 0.0232583 |
| TMEM132D | transmembrane protein 132D | 0.0231363 |
| MMP12 | matrix metallopeptidase 12 | 0.0230882 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0228465 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0228189 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0227647 |
| INTS6 | integrator complex subunit 6 | 0.0225208 |
| AUTS2 | autism susceptibility candidate 2 | 0.022104 |
| SLC41A2 | solute carrier family 41 (magnesium transporter), member 2 | 0.0218807 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0218754 |
| LDHA | lactate dehydrogenase A | 0.0218297 |
| EPHA6 | EPH receptor A6 | 0.021796 |
| GOLGB1 | golgin B1 | 0.020948 |
| PHF3 | PHD finger protein 3 | 0.0206108 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0205719 |
| EHBP1 | EH domain binding protein 1 | 0.0204062 |
| MORF4L2 | mortality factor 4 like 2 | 0.0203181 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0201896 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0201686 |
| SLC35F5 | solute carrier family 35, member F5 | 0.0201267 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0200978 |
| ARRDC3 | arrestin domain containing 3 | 0.020062 |
| SSR1 | signal sequence receptor, alpha | 0.0200501 |
| NOTCH2 | notch 2 | 0.02002 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.019847 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | 0.0196869 |
| ZNF638 | zinc finger protein 638 | 0.0195911 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0195013 |
| FBXO32 | F-box protein 32 | 0.0192489 |
| SERINC1 | serine incorporator 1 | 0.0191511 |
| STC1 | stanniocalcin 1 | 0.0191378 |
| CEP112 | centrosomal protein 112kDa | 0.0190618 |
| RPL3 | ribosomal protein L3 | 0.0190009 |
| CRYBG3 | beta-gamma crystallin domain containing 3 | 0.018897 |
| PRKCE | protein kinase C, epsilon | 0.01883 |
| CDK13 | cyclin-dependent kinase 13 | 0.0186761 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0186413 |
| EGFR | epidermal growth factor receptor | 0.0185574 |
| CANX | calnexin | 0.0185127 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0184179 |
| TPM1 | tropomyosin 1 (alpha) | 0.0181814 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0180894 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0180171 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.180119 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.136089 |
| FN1 | fibronectin 1 | -0.135168 |
| HLA-B | major histocompatibility complex, class I, B | -0.105042 |
| FTL | ferritin, light polypeptide | -0.0865984 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0754554 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0698689 |
| ADM | adrenomedullin | -0.0648559 |
| IER3 | immediate early response 3 | -0.0615026 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0607307 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0551436 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0540221 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0534604 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0508564 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0505603 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0493427 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0483886 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0465594 |
| TAPBP | TAP binding protein (tapasin) | -0.0448132 |
| RTN4 | reticulon 4 | -0.0433585 |
| CCNL1 | cyclin L1 | -0.0431045 |
| WDR45B | WD repeat domain 45B | -0.0401906 |
| BICC1 | BicC family RNA binding protein 1 | -0.0396851 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0389702 |
| FLNA | filamin A, alpha | -0.0375478 |
| TMSB10 | thymosin beta 10 | -0.0366109 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0362732 |
| TUBB | tubulin, beta class I | -0.035781 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0350088 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.034821 |
| ANXA2 | annexin A2 | -0.0346902 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0343652 |
| RPS24 | ribosomal protein S24 | -0.0340312 |
| OGA | O-GlcNAcase | -0.0325767 |
| ACTG1 | actin gamma 1 | -0.0324205 |
| TMEM41B | transmembrane protein 41B | -0.0318123 |
| UBC | ubiquitin C | -0.0312464 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0310116 |
| MT2A | metallothionein 2A | -0.0308837 |
| MSN | moesin | -0.030526 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0305082 |
| ATP13A3 | ATPase type 13A3 | -0.0304506 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0302675 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0300983 |
| COL1A1 | collagen, type I, alpha 1 | -0.0297288 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0295979 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0293724 |
| FLNB | filamin B, beta | -0.0291416 |
| TMEM123 | transmembrane protein 123 | -0.0288498 |
| RPLP0 | ribosomal protein, large, P0 | -0.0286859 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0280928 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0277015 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0268488 |
| RHOA | ras homolog family member A | -0.0261534 |
| ERBIN | erbb2 interacting protein | -0.025578 |
| EGR1 | early growth response 1 | -0.0255553 |
| WTAP | Wilms tumor 1 associated protein | -0.0255114 |
| ZNF207 | zinc finger protein 207 | -0.025424 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0252028 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0251949 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0250176 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.024998 |
| HLA-E | major histocompatibility complex, class I, E | -0.0248826 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | -0.0247771 |
| JMJD1C | jumonji domain containing 1C | -0.0244542 |
| SPAG9 | sperm associated antigen 9 | -0.0244511 |
| RYBP | RING1 and YY1 binding protein | -0.0243221 |
| CD99 | CD99 molecule | -0.0241834 |
| RBMX | RNA binding motif protein, X-linked | -0.0240654 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0240153 |
| H3-3B | H3.3 histone B | -0.0237723 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.023767 |
| RPS23 | ribosomal protein S23 | -0.023651 |
| NDRG1 | N-myc downstream regulated 1 | -0.0234204 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | -0.0231947 |
| RPS13 | ribosomal protein S13 | -0.0229856 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0229795 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0228544 |
| PAWR | PRKC, apoptosis, WT1, regulator | -0.0228536 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0228363 |
| RPL35A | ribosomal protein L35a | -0.0224934 |
| RACK1 | receptor for activated C kinase 1 | -0.0224316 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0222605 |
| VCL | vinculin | -0.0220337 |
| MAP4 | microtubule-associated protein 4 | -0.0220278 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0219244 |
| PHIP | pleckstrin homology domain interacting protein | -0.0218986 |
| ARF4 | ADP-ribosylation factor 4 | -0.0218962 |
| RPL27A | ribosomal protein L27a | -0.0218085 |
| CTSD | cathepsin D | -0.0217719 |
| PFN1 | profilin 1 | -0.0215212 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0212809 |
| JUN | jun proto-oncogene | -0.0210551 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0210488 |
| RLF | rearranged L-myc fusion | -0.0209254 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0206653 |
| ZNF292 | zinc finger protein 292 | -0.0204659 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0203315 |
| RPS11 | ribosomal protein S11 | -0.0202344 |
| RHEB | Ras homolog enriched in brain | -0.0201566 |
