| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SAMD4A | sterile alpha motif domain containing 4A | 0.0626066 |
| PDE10A | phosphodiesterase 10A | 0.0614783 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | 0.0567951 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0548038 |
| EFNA5 | ephrin-A5 | 0.052786 |
| PRELID2 | PRELI domain containing 2 | 0.0487018 |
| MED13L | mediator complex subunit 13-like | 0.0478922 |
| MSN | moesin | 0.0464266 |
| CD44 | CD44 molecule (Indian blood group) | 0.0460393 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0460251 |
| ACTN4 | actinin, alpha 4 | 0.0453501 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0445388 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0431592 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0425906 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0419193 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0417704 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0408431 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0407637 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0403854 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0395681 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0393685 |
| HMGA2 | high mobility group AT-hook 2 | 0.038456 |
| MYO10 | myosin X | 0.0368933 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0368794 |
| GPC6 | glypican 6 | 0.0367969 |
| MYOF | myoferlin | 0.0363871 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0353665 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0349419 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0345602 |
| CUX1 | cut-like homeobox 1 | 0.0341763 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0340696 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0340638 |
| WTAP | Wilms tumor 1 associated protein | 0.0337665 |
| IL6 | interleukin 6 | 0.033277 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0329729 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0320806 |
| TNS3 | tensin 3 | 0.032039 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.0318279 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0315943 |
| MED12 | mediator complex subunit 12 | 0.0310237 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | 0.0306964 |
| OSBPL8 | oxysterol binding protein-like 8 | 0.0305912 |
| YBX3 | Y box binding protein 3 | 0.0304075 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0303346 |
| MSI2 | musashi RNA-binding protein 2 | 0.0299554 |
| DARS1 | aspartyl-tRNA synthetase 1 | 0.0285557 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0285067 |
| SDC2 | syndecan 2 | 0.0284619 |
| RASA2 | RAS p21 protein activator 2 | 0.0284005 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0278131 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0276988 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0275948 |
| PRKCE | protein kinase C, epsilon | 0.0275786 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0270895 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0268436 |
| HDAC2 | histone deacetylase 2 | 0.0267405 |
| EREG | epiregulin | 0.0262957 |
| CDK13 | cyclin-dependent kinase 13 | 0.0260626 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0259586 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.025912 |
| ANKRD13C | ankyrin repeat domain 13C | 0.0258314 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0258087 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0257219 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0256895 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0256882 |
| THBS1 | thrombospondin 1 | 0.0254387 |
| NCKAP5 | NCK-associated protein 5 | 0.025297 |
| FAT1 | FAT atypical cadherin 1 | 0.0251336 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0251066 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0251046 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0247956 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0247687 |
| SNX9 | sorting nexin 9 | 0.0247289 |
| ANXA1 | annexin A1 | 0.0246503 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0244524 |
| ATXN1 | ataxin 1 | 0.0244393 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0244035 |
| FOXN3 | forkhead box N3 | 0.0243409 |
| FOXP1 | forkhead box P1 | 0.024303 |
| PARD3 | par-3 family cell polarity regulator | 0.0242606 |
| NAV2 | neuron navigator 2 | 0.024237 |
| RAB21 | RAB21, member RAS oncogene family | 0.0241634 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0237765 |
| GDA | guanine deaminase | 0.0234779 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0234006 |
| RAB31 | RAB31, member RAS oncogene family | 0.0233355 |
| ETV6 | ets variant 6 | 0.0233147 |
| AFDN | afadin, adherens junction formation factor | 0.0232708 |
| PLEKHA2 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2 | 0.0231258 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0229841 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0229664 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.022956 |
| CEP170 | centrosomal protein 170kDa | 0.0227749 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0227235 |
| RORA | RAR-related orphan receptor A | 0.0226298 |
| NUP58 | nucleoporin 58 | 0.0226047 |
| CCND1 | cyclin D1 | 0.0224508 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0224077 |
| TRIM33 | tripartite motif containing 33 | 0.022347 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0222799 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.314685 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.245311 |
| TMSB10 | thymosin beta 10 | -0.182671 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.130425 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.112721 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.108668 |
| VIM | vimentin | -0.107518 |
| NDRG1 | N-myc downstream regulated 1 | -0.099385 |
| B2M | beta-2-microglobulin | -0.09596 |
| CALR | calreticulin | -0.0920467 |
| MT2A | metallothionein 2A | -0.0906661 |
| CANX | calnexin | -0.0884638 |
| FTL | ferritin, light polypeptide | -0.0816568 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0796221 |
| HLA-B | major histocompatibility complex, class I, B | -0.0692241 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0684222 |
| CALU | calumenin | -0.0655704 |
| ADM | adrenomedullin | -0.0624849 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0619187 |
| EGFR | epidermal growth factor receptor | -0.0610103 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0603308 |
| PTMA | prothymosin, alpha | -0.0594915 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0588454 |
| RRBP1 | ribosome binding protein 1 | -0.0587091 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0586834 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0542463 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0538733 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0532168 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0524415 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0498135 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0485524 |
| HLA-C | major histocompatibility complex, class I, C | -0.0480548 |
| ENO1 | enolase 1, (alpha) | -0.0470325 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0467999 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0465036 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0455863 |
| SEC24D | SEC24 family member D | -0.045334 |
| XPO1 | exportin 1 | -0.0449693 |
| GLG1 | golgi glycoprotein 1 | -0.0446801 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0437777 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0433867 |
| HLA-A | major histocompatibility complex, class I, A | -0.0408019 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.0407312 |
| VEGFA | vascular endothelial growth factor A | -0.0405795 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0402462 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0401019 |
| PRKCA | protein kinase C, alpha | -0.0400698 |
| LOX | lysyl oxidase | -0.0400518 |
| RPL37A | ribosomal protein L37a | -0.0392195 |
| LMNA | lamin A/C | -0.0389297 |
| HM13 | histocompatibility (minor) 13 | -0.0385949 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0382422 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0382033 |
| PGK1 | phosphoglycerate kinase 1 | -0.0381085 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.037762 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0376562 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0370986 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | -0.0367448 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0366482 |
| PKM | pyruvate kinase, muscle | -0.0354259 |
| CLTC | clathrin, heavy chain (Hc) | -0.0353586 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0353015 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0352101 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.035034 |
| RPS8 | ribosomal protein S8 | -0.0344623 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0342885 |
| FUS | FUS RNA binding protein | -0.0337386 |
| S100A10 | S100 calcium binding protein A10 | -0.0333371 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.033292 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0331525 |
| SCFD1 | sec1 family domain containing 1 | -0.0330034 |
| CD99 | CD99 molecule | -0.0329155 |
| COG6 | component of oligomeric golgi complex 6 | -0.0320143 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | -0.0318931 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0317696 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0316784 |
| LDHA | lactate dehydrogenase A | -0.0308858 |
| CAVIN1 | caveolae associated protein 1 | -0.0307243 |
| YIPF5 | Yip1 domain family, member 5 | -0.0306424 |
| HDLBP | high density lipoprotein binding protein | -0.0303688 |
| MORF4L2 | mortality factor 4 like 2 | -0.0300432 |
| COL5A1 | collagen, type V, alpha 1 | -0.0298035 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0297332 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0293666 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0291708 |
| MMP12 | matrix metallopeptidase 12 | -0.0291557 |
| RAB6A | RAB6A, member RAS oncogene family | -0.029094 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0289031 |
| RYBP | RING1 and YY1 binding protein | -0.0286906 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0285587 |
| FKBP10 | FK506 binding protein 10, 65 kDa | -0.0284659 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0284355 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0283779 |
| H3-3B | H3.3 histone B | -0.0283448 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0279194 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0278071 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0275468 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0271545 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0269901 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0269251 |
