| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.159613 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.150733 |
| MT2A | metallothionein 2A | 0.131202 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.128599 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.117825 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.116517 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.111763 |
| CENPF | centromere protein F, 350/400kDa | 0.0854643 |
| VIM | vimentin | 0.0828681 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0752316 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0705149 |
| RPS12 | ribosomal protein S12 | 0.0620914 |
| B2M | beta-2-microglobulin | 0.0588813 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0584494 |
| PTMA | prothymosin, alpha | 0.0583222 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0573207 |
| RNF145 | ring finger protein 145 | 0.0553416 |
| RPS6 | ribosomal protein S6 | 0.0538905 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0534732 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.052626 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0525894 |
| OGA | O-GlcNAcase | 0.0520092 |
| ZNF292 | zinc finger protein 292 | 0.0515807 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.050915 |
| MKI67 | marker of proliferation Ki-67 | 0.0500406 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0493545 |
| NEK7 | NIMA-related kinase 7 | 0.0489618 |
| EREG | epiregulin | 0.0487102 |
| ETNK1 | ethanolamine kinase 1 | 0.0481744 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0473464 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0470131 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0468976 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0456826 |
| VMP1 | vacuole membrane protein 1 | 0.0454615 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0441442 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0438417 |
| RPL26 | ribosomal protein L26 | 0.0434615 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0426054 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.042096 |
| AHR | aryl hydrocarbon receptor | 0.0411451 |
| SMYD3 | SET and MYND domain containing 3 | 0.0410453 |
| ANLN | anillin, actin binding protein | 0.0410196 |
| RPL12 | ribosomal protein L12 | 0.0399274 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0395163 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0387293 |
| FNBP1 | formin binding protein 1 | 0.0385039 |
| SMOX | spermine oxidase | 0.0382489 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0380942 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0380896 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0380242 |
| TOP1 | topoisomerase (DNA) I | 0.0378689 |
| RBM39 | RNA binding motif protein 39 | 0.0374271 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | 0.0374233 |
| RPL37A | ribosomal protein L37a | 0.0367029 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0366182 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.03579 |
| UBE2K | ubiquitin-conjugating enzyme E2K | 0.0357629 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0348743 |
| RNF24 | ring finger protein 24 | 0.0347661 |
| RPL11 | ribosomal protein L11 | 0.034723 |
| PRELID2 | PRELI domain containing 2 | 0.0345409 |
| WDR26 | WD repeat domain 26 | 0.0344205 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0343439 |
| RPL31 | ribosomal protein L31 | 0.0342834 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0342717 |
| RPS19 | ribosomal protein S19 | 0.0341931 |
| PELO | pelota homolog (Drosophila) | 0.0341894 |
| RO60 | Ro60, Y RNA binding protein | 0.0341035 |
| FBXL5 | F-box and leucine-rich repeat protein 5 | 0.0337322 |
| FNDC3B | fibronectin type III domain containing 3B | 0.033589 |
| RACK1 | receptor for activated C kinase 1 | 0.033453 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0331871 |
| TXNIP | thioredoxin interacting protein | 0.0330426 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0328947 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.032622 |
| COG5 | component of oligomeric golgi complex 5 | 0.0325676 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0324878 |
| CANX | calnexin | 0.0324187 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0322286 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0322023 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0321173 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0315923 |
| SEPTIN7 | septin 7 | 0.0314638 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0311194 |
| PGK1 | phosphoglycerate kinase 1 | 0.0306561 |
| TFG | TRK-fused gene | 0.030572 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0302103 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0301439 |
| CD44 | CD44 molecule (Indian blood group) | 0.0301212 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0299303 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0298606 |
| RBM25 | RNA binding motif protein 25 | 0.0297997 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0297854 |
| ZFR | zinc finger RNA binding protein | 0.0293131 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0290947 |
| SFXN1 | sideroflexin 1 | 0.0290196 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0290194 |
| MCTP2 | multiple C2 domains, transmembrane 2 | 0.0287792 |
| CAB39 | calcium binding protein 39 | 0.028761 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.028528 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.304262 |
| NRG1 | neuregulin 1 | -0.205565 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0959712 |
| STC2 | stanniocalcin 2 | -0.0865798 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0821781 |
| HMGA2 | high mobility group AT-hook 2 | -0.0700025 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0688976 |
| NDRG1 | N-myc downstream regulated 1 | -0.0657534 |
| RAI14 | retinoic acid induced 14 | -0.0645783 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0619603 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0605575 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0600976 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0581022 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0539506 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0525195 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0514131 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0502459 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0474991 |
| LMNA | lamin A/C | -0.0474606 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0450222 |
| EFNA5 | ephrin-A5 | -0.0437386 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0421495 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0419485 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0407096 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0396907 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | -0.0391483 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0389986 |
| VEGFA | vascular endothelial growth factor A | -0.0384877 |
| PLIN2 | perilipin 2 | -0.038304 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0377432 |
| CADM1 | cell adhesion molecule 1 | -0.0368742 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0355806 |
| SYT1 | synaptotagmin I | -0.0350783 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0340189 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0337275 |
| ACTG1 | actin gamma 1 | -0.0333008 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0330418 |
| EGR1 | early growth response 1 | -0.0323971 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.031852 |
| EZR | ezrin | -0.0318488 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.031728 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0312785 |
| TMSB4X | thymosin beta 4, X-linked | -0.0300672 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0300116 |
| JUN | jun proto-oncogene | -0.0293739 |
| AGPAT4 | 1-acylglycerol-3-phosphate O-acyltransferase 4 | -0.0287241 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0276505 |
| RFX2 | regulatory factor X, 2 (influences HLA class II expression) | -0.0275822 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.027252 |
| HLA-B | major histocompatibility complex, class I, B | -0.0269661 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0268909 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0266692 |
| MAP1B | microtubule-associated protein 1B | -0.0263743 |
| FBN1 | fibrillin 1 | -0.0263066 |
| TGFA | transforming growth factor, alpha | -0.0262536 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0255888 |
| TENM4 | teneurin transmembrane protein 4 | -0.0253945 |
| CTSD | cathepsin D | -0.0253261 |
| TNS3 | tensin 3 | -0.0251601 |
| MYO1E | myosin IE | -0.025085 |
| MCL1 | myeloid cell leukemia 1 | -0.0249541 |
| SIRT1 | sirtuin 1 | -0.0246216 |
| SQSTM1 | sequestosome 1 | -0.0242806 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0233833 |
| VAC14 | Vac14 homolog (S. cerevisiae) | -0.0230936 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0230279 |
| GLUL | glutamate-ammonia ligase | -0.0229813 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0228781 |
| CTBP2 | C-terminal binding protein 2 | -0.0228658 |
| AHRR | aryl-hydrocarbon receptor repressor | -0.0227683 |
| CNIH3 | cornichon family AMPA receptor auxiliary protein 3 | -0.0227367 |
| MMP13 | matrix metallopeptidase 13 | -0.022519 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0221194 |
| ARHGAP35 | Rho GTPase activating protein 35 | -0.0215378 |
| TNRC6C | trinucleotide repeat containing 6C | -0.0214069 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0213261 |
| PALLD | palladin, cytoskeletal associated protein | -0.0212081 |
| EMP1 | epithelial membrane protein 1 | -0.0211891 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.021098 |
| ABR | active BCR-related | -0.0209373 |
| MTSS1 | metastasis suppressor 1 | -0.020799 |
| RASAL2 | RAS protein activator like 2 | -0.0207243 |
| IL6 | interleukin 6 | -0.0202582 |
| AOPEP | aminopeptidase O (putative) | -0.0202331 |
| DYRK3 | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 | -0.0201318 |
| MYOF | myoferlin | -0.0201143 |
| PLEC | plectin | -0.0199833 |
| TCIM | transcriptional and immune response regulator | -0.0197432 |
| ATN1 | atrophin 1 | -0.0197353 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0197342 |
| MYADM | myeloid-associated differentiation marker | -0.0196775 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0195242 |
| CUX1 | cut-like homeobox 1 | -0.0194653 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | -0.0193852 |
| SHC3 | SHC (Src homology 2 domain containing) transforming protein 3 | -0.0193523 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0191898 |
| IGF2 | insulin-like growth factor 2 | -0.01911 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0191037 |
| POTEF | POTE ankyrin domain family, member F | -0.0190277 |
| CALR | calreticulin | -0.0190242 |
