| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in SW1417 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_SW1417 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PTMA | prothymosin, alpha | 0.0840175 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0398518 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0380376 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0359602 |
| RPS12 | ribosomal protein S12 | 0.0357631 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0342972 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0334207 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0322605 |
| NCKAP1 | NCK-associated protein 1 | 0.0289178 |
| USP3 | ubiquitin specific peptidase 3 | 0.0275691 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0274257 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0249298 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0248546 |
| TMF1 | TATA element modulatory factor 1 | 0.0247577 |
| RPS3 | ribosomal protein S3 | 0.0247101 |
| SET | SET nuclear proto-oncogene | 0.0236967 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0236101 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.022608 |
| ZNF706 | zinc finger protein 706 | 0.0225152 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | 0.0224956 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0212564 |
| RNF149 | ring finger protein 149 | 0.0209929 |
| RYK | receptor-like tyrosine kinase | 0.0208745 |
| RNF145 | ring finger protein 145 | 0.0207987 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0205215 |
| ARHGAP32 | Rho GTPase activating protein 32 | 0.0203678 |
| HDGF | hepatoma-derived growth factor | 0.0201993 |
| SETD5 | SET domain containing 5 | 0.019604 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0191804 |
| XPO1 | exportin 1 | 0.0191693 |
| ATL2 | atlastin GTPase 2 | 0.0191325 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0188435 |
| RPS2 | ribosomal protein S2 | 0.0187211 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0186006 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.018366 |
| PDS5B | PDS5 cohesin associated factor B | 0.0180571 |
| RPL37A | ribosomal protein L37a | 0.0179204 |
| FMR1 | fragile X mental retardation 1 | 0.0179027 |
| TPM3 | tropomyosin 3 | 0.0177747 |
| H2AC6 | H2A clustered histone 6 | 0.0172571 |
| RPL3 | ribosomal protein L3 | 0.0170425 |
| ARRDC3 | arrestin domain containing 3 | 0.0169071 |
| CTSA | cathepsin A | 0.01688 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0168682 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0164089 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0164045 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0162497 |
| CCNL1 | cyclin L1 | 0.0157476 |
| RPS17 | ribosomal protein S17 | 0.0154165 |
| ZFR | zinc finger RNA binding protein | 0.0154107 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | 0.014898 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | 0.0148388 |
| CDK19 | cyclin-dependent kinase 19 | 0.0147197 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0146096 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0144243 |
| ANP32B | acidic (leucine-rich) nuclear phosphoprotein 32 family, member B | 0.0141585 |
| TMA7 | translation machinery associated 7 homolog (S. cerevisiae) | 0.0138561 |
| IWS1 | IWS1 homolog (S. cerevisiae) | 0.0138068 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0137657 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0136964 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0135819 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0133305 |
| PNN | pinin, desmosome associated protein | 0.0131576 |
| KPNA1 | karyopherin alpha 1 (importin alpha 5) | 0.0130363 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0129505 |
| GRID1 | glutamate receptor, ionotropic, delta 1 | 0.0127162 |
| TOP6BL | TOP6B like initiator of meiotic double strand breaks | 0.0126616 |
| NDRG1 | N-myc downstream regulated 1 | 0.0126338 |
| DPY19L1 | dpy-19-like 1 (C. elegans) | 0.012524 |
| KDELR1 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 | 0.0124697 |
| H1-4 | H1.4 linker histone, cluster member | 0.0124557 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0124255 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0124184 |
| TMEM39A | transmembrane protein 39A | 0.0123997 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | 0.0123122 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0122346 |
| TFG | TRK-fused gene | 0.0122342 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0121982 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0119834 |
| CDCP1 | CUB domain containing protein 1 | 0.011829 |
| RPS6 | ribosomal protein S6 | 0.0117152 |
| OGA | O-GlcNAcase | 0.0116721 |
| TMEM165 | transmembrane protein 165 | 0.0116238 |
| HOXB6 | homeobox B6 | 0.0115553 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0115367 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0115079 |
| ARL8B | ADP-ribosylation factor-like 8B | 0.0114357 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0114119 |
| HACD2 | 3-hydroxyacyl-CoA dehydratase 2 | 0.0113716 |
| CCNC | cyclin C | 0.011351 |
| NAA16 | N(alpha)-acetyltransferase 16, NatA auxiliary subunit | 0.0113225 |
| KDM1A | lysine (K)-specific demethylase 1A | 0.0113024 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0112886 |
| B2M | beta-2-microglobulin | 0.0112835 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0112509 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0111701 |
| RO60 | Ro60, Y RNA binding protein | 0.0111461 |
| ANKRD10 | ankyrin repeat domain 10 | 0.010995 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0109899 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0109506 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.153152 |
| EZR | ezrin | -0.0910707 |
| BCL2L1 | BCL2-like 1 | -0.0893024 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0852096 |
| EGR1 | early growth response 1 | -0.0845208 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0811856 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0780081 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0741346 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0727464 |
| LOC112694756 | uncharaterized LOC112694756 | -0.069052 |
| MYO1E | myosin IE | -0.0673409 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0652629 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0644083 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0587371 |
| FTL | ferritin, light polypeptide | -0.0581793 |
| VCL | vinculin | -0.0575631 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0557913 |
| NEBL | nebulette | -0.055124 |
| RBM39 | RNA binding motif protein 39 | -0.0537671 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0520019 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0516977 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0501015 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0499434 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0498253 |
| ACTN4 | actinin, alpha 4 | -0.0494875 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0485121 |
| TGFA | transforming growth factor, alpha | -0.0480589 |
| EIF3H | eukaryotic translation initiation factor 3, subunit H | -0.0479267 |
| TJP1 | tight junction protein 1 | -0.0475661 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0471177 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0467463 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0467073 |
| SLC20A2 | solute carrier family 20 (phosphate transporter), member 2 | -0.0455774 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0444984 |
| WWC1 | WW and C2 domain containing 1 | -0.0442385 |
| RPL35A | ribosomal protein L35a | -0.0439768 |
| RHEB | Ras homolog enriched in brain | -0.0436294 |
| KRT18 | keratin 18, type I | -0.0420889 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0418234 |
| MYOF | myoferlin | -0.0415764 |
| OXSR1 | oxidative stress responsive 1 | -0.0414264 |
| FBXO11 | F-box protein 11 | -0.0405115 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0401882 |
| GOLGB1 | golgin B1 | -0.0400315 |
| HDLBP | high density lipoprotein binding protein | -0.0398099 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0388911 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0386256 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.038531 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0385078 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0384817 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.037864 |
| ANXA2 | annexin A2 | -0.0374664 |
| TOP1 | topoisomerase (DNA) I | -0.0370958 |
| AHNAK | AHNAK nucleoprotein | -0.0370586 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | -0.0368691 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0361319 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0359501 |
| PLSCR1 | phospholipid scramblase 1 | -0.035771 |
| ETV6 | ets variant 6 | -0.0357573 |
| TMSB10 | thymosin beta 10 | -0.0355531 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0354468 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0348495 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0346546 |
| KCNH8 | potassium channel, voltage gated eag related subfamily H, member 8 | -0.0346145 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0342706 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0342587 |
| CDK13 | cyclin-dependent kinase 13 | -0.0339268 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0338382 |
| UBC | ubiquitin C | -0.0335585 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0333588 |
| RPL23 | ribosomal protein L23 | -0.0329893 |
| GNAS | GNAS complex locus | -0.032503 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0324613 |
| ARF1 | ADP-ribosylation factor 1 | -0.0323865 |
| FHL2 | four and a half LIM domains 2 | -0.0323006 |
| PATJ | PATJ crumbs cell polarity complex component | -0.032164 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0321174 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0321067 |
| XRCC5 | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining) | -0.0319642 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0318608 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0318368 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0313408 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0313332 |
| MORF4L2 | mortality factor 4 like 2 | -0.0306507 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0306367 |
| NUP98 | nucleoporin 98kDa | -0.0304026 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0303952 |
| MX2 | MX dynamin-like GTPase 2 | -0.0303026 |
| SPAG9 | sperm associated antigen 9 | -0.0302844 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0301972 |
| SQSTM1 | sequestosome 1 | -0.0301676 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0301589 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0301345 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0301099 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0300214 |
| UBAP2 | ubiquitin associated protein 2 | -0.0300021 |
| PARVA | parvin, alpha | -0.0298494 |
| KRT20 | keratin 20, type I | -0.0298424 |
| LDHA | lactate dehydrogenase A | -0.0298286 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0296122 |
