| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fostamatinib (disodium hexahydrate) perturbation in hTERT-HPNE cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fostamatinib (disodium hexahydrate)_hTERT-HPNE drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.381417 |
| STC1 | stanniocalcin 1 | 0.161978 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.137477 |
| FAM13A | family with sequence similarity 13, member A | 0.136521 |
| INHBA | inhibin, beta A | 0.101582 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.100227 |
| B2M | beta-2-microglobulin | 0.0948124 |
| PTMA | prothymosin, alpha | 0.08415 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.080819 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0790812 |
| GOLGA4 | golgin A4 | 0.0770624 |
| TMSB10 | thymosin beta 10 | 0.0719565 |
| NDRG1 | N-myc downstream regulated 1 | 0.0714665 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0693813 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0688714 |
| FTL | ferritin, light polypeptide | 0.0675579 |
| RPS6 | ribosomal protein S6 | 0.0669738 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0663696 |
| MT2A | metallothionein 2A | 0.063501 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0628772 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0612717 |
| SPAG9 | sperm associated antigen 9 | 0.0583161 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0569241 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0563598 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0555454 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0549628 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0546999 |
| RPS12 | ribosomal protein S12 | 0.0541067 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0517525 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0513013 |
| PGK1 | phosphoglycerate kinase 1 | 0.0504616 |
| LDHA | lactate dehydrogenase A | 0.0486804 |
| RPS8 | ribosomal protein S8 | 0.0484669 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0476011 |
| CANX | calnexin | 0.0468392 |
| RPL37A | ribosomal protein L37a | 0.0457989 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0457907 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0450108 |
| FMNL2 | formin-like 2 | 0.0449875 |
| ADM | adrenomedullin | 0.0448489 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0440102 |
| ENO1 | enolase 1, (alpha) | 0.0434832 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0430174 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0418604 |
| RPLP1 | ribosomal protein, large, P1 | 0.0417052 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0414802 |
| RPL12 | ribosomal protein L12 | 0.0394703 |
| NUP58 | nucleoporin 58 | 0.0392711 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0391328 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0375879 |
| MXI1 | MAX interactor 1, dimerization protein | 0.037435 |
| ZNF292 | zinc finger protein 292 | 0.0371934 |
| IER3 | immediate early response 3 | 0.0371477 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0371373 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.03677 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0365693 |
| ATP13A3 | ATPase type 13A3 | 0.0359222 |
| RNF145 | ring finger protein 145 | 0.0353137 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | 0.0341108 |
| SET | SET nuclear proto-oncogene | 0.0338857 |
| RPL31 | ribosomal protein L31 | 0.0338702 |
| OGA | O-GlcNAcase | 0.0337799 |
| RPS3 | ribosomal protein S3 | 0.0334505 |
| SRGN | serglycin | 0.0330469 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0329095 |
| CALU | calumenin | 0.0327695 |
| RPS19 | ribosomal protein S19 | 0.0327191 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.032406 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0316503 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0313063 |
| MMP12 | matrix metallopeptidase 12 | 0.0311055 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0310083 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.0300843 |
| RPL11 | ribosomal protein L11 | 0.0298269 |
| RPS17 | ribosomal protein S17 | 0.0297678 |
| RPL35A | ribosomal protein L35a | 0.029407 |
| SQSTM1 | sequestosome 1 | 0.0289868 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0287857 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0287415 |
| DST | dystonin | 0.0287143 |
| ANXA2 | annexin A2 | 0.0286594 |
| RPL23 | ribosomal protein L23 | 0.028569 |
| ARRDC3 | arrestin domain containing 3 | 0.0285057 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0284324 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0281385 |
| RPS27A | ribosomal protein S27a | 0.0280202 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0279556 |
| RAI1 | retinoic acid induced 1 | 0.0279067 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0278905 |
| HLA-A | major histocompatibility complex, class I, A | 0.0273184 |
| INSIG1 | insulin induced gene 1 | 0.0271669 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0271281 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.027116 |
| RPL5 | ribosomal protein L5 | 0.0270981 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0269901 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0268742 |
| TNPO1 | transportin 1 | 0.0268072 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0266975 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0266315 |
| S100A6 | S100 calcium binding protein A6 | 0.026567 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.202763 |
| COL6A3 | collagen, type VI, alpha 3 | -0.155913 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0955245 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0830671 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0772989 |
| MYO10 | myosin X | -0.0692557 |
| HMGA2 | high mobility group AT-hook 2 | -0.0603851 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0594439 |
| VCL | vinculin | -0.0539953 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0534294 |
| ADAMTS12 | ADAM metallopeptidase with thrombospondin type 1 motif, 12 | -0.0498162 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0488225 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0481261 |
| NAV1 | neuron navigator 1 | -0.0453252 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0452342 |
| EGFR | epidermal growth factor receptor | -0.043656 |
| COL5A3 | collagen, type V, alpha 3 | -0.0420464 |
| SASH1 | SAM and SH3 domain containing 1 | -0.0397283 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0351113 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0346906 |
| STARD13 | StAR-related lipid transfer (START) domain containing 13 | -0.033719 |
| OSMR | oncostatin M receptor | -0.0333576 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0314039 |
| CALD1 | caldesmon 1 | -0.0310428 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0307687 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0302639 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0299522 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0299258 |
| FRMD4A | FERM domain containing 4A | -0.0295641 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0288056 |
| RFX8 | RFX family member 8, lacking RFX DNA binding domain | -0.0283619 |
| VEGFA | vascular endothelial growth factor A | -0.0280212 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.0273211 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0266492 |
| CLMP | CXADR-like membrane protein | -0.0261876 |
| ACTN1 | actinin, alpha 1 | -0.0254983 |
| PDGFRB | platelet-derived growth factor receptor, beta polypeptide | -0.0251824 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0247601 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.0247255 |
| RAI14 | retinoic acid induced 14 | -0.0245859 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0243828 |
| MAP1B | microtubule-associated protein 1B | -0.0241991 |
| EGR1 | early growth response 1 | -0.0238205 |
| RSU1 | Ras suppressor protein 1 | -0.0234782 |
| ARHGAP24 | Rho GTPase activating protein 24 | -0.0231326 |
| GLIS3 | GLIS family zinc finger 3 | -0.0227633 |
| KIAA1549L | KIAA1549-like | -0.0227196 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | -0.0221519 |
| PALLD | palladin, cytoskeletal associated protein | -0.022083 |
| SPRY4 | sprouty homolog 4 (Drosophila) | -0.0220423 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0219602 |
| EMP1 | epithelial membrane protein 1 | -0.0214409 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0210514 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0208379 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0207107 |
| COL5A1 | collagen, type V, alpha 1 | -0.0206384 |
| WNT2B | wingless-type MMTV integration site family, member 2B | -0.0205264 |
| SEPTIN11 | septin 11 | -0.0202355 |
| ARHGAP31 | Rho GTPase activating protein 31 | -0.0198943 |
| ITGA11 | integrin, alpha 11 | -0.0198338 |
| CDH13 | cadherin 13 | -0.0197436 |
| PRRX1 | paired related homeobox 1 | -0.0194379 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0193042 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0191762 |
| FLNA | filamin A, alpha | -0.0186866 |
| VMP1 | vacuole membrane protein 1 | -0.0185101 |
| NABP1 | nucleic acid binding protein 1 | -0.0183848 |
| CYTH3 | cytohesin 3 | -0.0183557 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | -0.0181255 |
| OXR1 | oxidation resistance 1 | -0.0181222 |
| CCDC102B | coiled-coil domain containing 102B | -0.0180716 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0179306 |
| FOXP1 | forkhead box P1 | -0.0173969 |
| COL6A2 | collagen, type VI, alpha 2 | -0.0171778 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0169519 |
| SIK2 | salt-inducible kinase 2 | -0.0166863 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.016513 |
| RASA3 | RAS p21 protein activator 3 | -0.0160815 |
| SH3PXD2A | SH3 and PX domains 2A | -0.0158014 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0156285 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0155673 |
| SMAD3 | SMAD family member 3 | -0.0155565 |
| NECTIN3 | nectin cell adhesion molecule 3 | -0.0152358 |
| NOTCH2 | notch 2 | -0.0152311 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.015187 |
| CDPF1 | cysteine-rich, DPF motif domain containing 1 | -0.0151639 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.014883 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.014852 |
| LYST | lysosomal trafficking regulator | -0.0146735 |
| DNER | delta/notch-like EGF repeat containing | -0.0145815 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0144633 |
| PLOD1 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1 | -0.0143414 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.014155 |
| ACLY | ATP citrate lyase | -0.0141174 |
| MMP14 | matrix metallopeptidase 14 (membrane-inserted) | -0.0140073 |
| MYADM | myeloid-associated differentiation marker | -0.0139941 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0138786 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | -0.0137321 |
| CD44 | CD44 molecule (Indian blood group) | -0.0136262 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0135866 |
