| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fulvestrant_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AREG | amphiregulin | 0.139446 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0741411 |
| CCNL1 | cyclin L1 | 0.0575573 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0480796 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0459083 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0373916 |
| PCBP2 | poly(rC) binding protein 2 | 0.0355334 |
| EDN1 | endothelin 1 | 0.0346115 |
| CPOX | coproporphyrinogen oxidase | 0.0339315 |
| KLHL24 | kelch-like family member 24 | 0.0315177 |
| CCN2 | cellular communication network factor 2 | 0.0300139 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0299448 |
| NEK7 | NIMA-related kinase 7 | 0.0298809 |
| ZNF292 | zinc finger protein 292 | 0.0284451 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0282095 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0277532 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0271884 |
| ECT2 | epithelial cell transforming 2 | 0.0271844 |
| TMEM41B | transmembrane protein 41B | 0.0271775 |
| NKTR | natural killer cell triggering receptor | 0.0270101 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0267713 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0266481 |
| CEP95 | centrosomal protein 95kDa | 0.026593 |
| YTHDC1 | YTH domain containing 1 | 0.0265669 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0256981 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0252476 |
| ATP11A | ATPase, class VI, type 11A | 0.0252224 |
| MATR3 | matrin 3 | 0.0251306 |
| WDR43 | WD repeat domain 43 | 0.0240879 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0240449 |
| TXNRD1 | thioredoxin reductase 1 | 0.0240024 |
| PNN | pinin, desmosome associated protein | 0.0233806 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.0230997 |
| CEP192 | centrosomal protein 192kDa | 0.02306 |
| PCM1 | pericentriolar material 1 | 0.0227216 |
| CDK19 | cyclin-dependent kinase 19 | 0.0223507 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0211942 |
| COG5 | component of oligomeric golgi complex 5 | 0.0207023 |
| XPO1 | exportin 1 | 0.0204676 |
| TBK1 | TANK-binding kinase 1 | 0.0203106 |
| BLTP1 | bridge-like lipid transfer protein family member 1 | 0.0199142 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0198846 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0197496 |
| OXR1 | oxidation resistance 1 | 0.0195152 |
| UBC | ubiquitin C | 0.0192386 |
| CXADR | coxsackie virus and adenovirus receptor | 0.0191548 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0191513 |
| RBM25 | RNA binding motif protein 25 | 0.0189822 |
| TPR | translocated promoter region, nuclear basket protein | 0.0189812 |
| MED13L | mediator complex subunit 13-like | 0.0189224 |
| PREPL | prolyl endopeptidase-like | 0.0182186 |
| CAMKMT | calmodulin-lysine N-methyltransferase | 0.0181486 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0178701 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0178335 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0177387 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0176949 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0176623 |
| EPHA6 | EPH receptor A6 | 0.0176284 |
| THOC1 | THO complex 1 | 0.0174849 |
| OGA | O-GlcNAcase | 0.0174787 |
| ETNK1 | ethanolamine kinase 1 | 0.0173884 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0173352 |
| RPL4 | ribosomal protein L4 | 0.0173351 |
| THOC2 | THO complex 2 | 0.0172999 |
| RNF145 | ring finger protein 145 | 0.017279 |
| QKI | QKI, KH domain containing, RNA binding | 0.017249 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0171407 |
| PDK4 | pyruvate dehydrogenase kinase, isozyme 4 | 0.0170509 |
| PLK2 | polo-like kinase 2 | 0.0169379 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0168428 |
| PALS2 | protein associated with LIN7 2, MAGUK p55 family member | 0.0168094 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0167761 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0167407 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0167187 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.0166559 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0164636 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0164276 |
| TENT4A | terminal nucleotidyltransferase 4A | 0.0163439 |
| ATP11B | ATPase, class VI, type 11B | 0.0163269 |
| RBM39 | RNA binding motif protein 39 | 0.0162521 |
| TFG | TRK-fused gene | 0.0162478 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0161046 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0160869 |
| FBXL20 | F-box and leucine-rich repeat protein 20 | 0.0160134 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0159791 |
| U2SURP | U2 snRNP-associated SURP domain containing | 0.0159741 |
| KIF5B | kinesin family member 5B | 0.0158404 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0155808 |
| DHX29 | DEAH (Asp-Glu-Ala-His) box polypeptide 29 | 0.0155586 |
| SUCO | SUN domain containing ossification factor | 0.01555 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0153151 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0152019 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.015195 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.015139 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0150174 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0149526 |
| RPRD2 | regulation of nuclear pre-mRNA domain containing 2 | 0.0149332 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0147974 |
| SLC49A4 | solute carrier family 49 member 4 | 0.0147033 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0146792 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.222975 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.168654 |
| HMGA2 | high mobility group AT-hook 2 | -0.157671 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.154377 |
| NLGN1 | neuroligin 1 | -0.152865 |
| VIM | vimentin | -0.134034 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.1097 |
| ACTG1 | actin gamma 1 | -0.104122 |
| TMSB10 | thymosin beta 10 | -0.098821 |
| PCDH7 | protocadherin 7 | -0.0808235 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0794417 |
| PTMA | prothymosin, alpha | -0.0772512 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0762562 |
| EHBP1 | EH domain binding protein 1 | -0.0727023 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0710166 |
| ASPH | aspartate beta-hydroxylase | -0.0700452 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0638489 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0635791 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0600125 |
| NHSL1 | NHS-like 1 | -0.0595225 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0582381 |
| RPS8 | ribosomal protein S8 | -0.0577634 |
| YAP1 | Yes-associated protein 1 | -0.0543131 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0538379 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0533882 |
| CANX | calnexin | -0.052964 |
| ZNF804A | zinc finger protein 804A | -0.0527075 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0524182 |
| BCHE | butyrylcholinesterase | -0.0521522 |
| RASAL2 | RAS protein activator like 2 | -0.0493204 |
| MMP12 | matrix metallopeptidase 12 | -0.0491824 |
| INTS6 | integrator complex subunit 6 | -0.0488987 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0485361 |
| CALR | calreticulin | -0.0464145 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0456928 |
| TPI1 | triosephosphate isomerase 1 | -0.0456331 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | -0.0456281 |
| DST | dystonin | -0.0454015 |
| ANXA1 | annexin A1 | -0.0445459 |
| CUX1 | cut-like homeobox 1 | -0.0441139 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0440321 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0437108 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0436456 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0433174 |
| ADIPOR2 | adiponectin receptor 2 | -0.0431983 |
| ENO1 | enolase 1, (alpha) | -0.0407199 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.039994 |
| RPL23 | ribosomal protein L23 | -0.0399688 |
| S100A10 | S100 calcium binding protein A10 | -0.0397118 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0395943 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0393575 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0389448 |
| RPS6 | ribosomal protein S6 | -0.0382346 |
| RPS3 | ribosomal protein S3 | -0.0372951 |
| TPM4 | tropomyosin 4 | -0.0370364 |
| MTAP | methylthioadenosine phosphorylase | -0.0358609 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0356636 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0340529 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0330021 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0329606 |
| DTNA | dystrobrevin, alpha | -0.0328472 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0326312 |
| HMGA1 | high mobility group AT-hook 1 | -0.0322932 |
| PTGES3 | prostaglandin E synthase 3 (cytosolic) | -0.0321368 |
| GNAS | GNAS complex locus | -0.0319236 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0319069 |
| GCG | glucagon | -0.0319044 |
| LDHA | lactate dehydrogenase A | -0.0318552 |
| RPL35A | ribosomal protein L35a | -0.0317858 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0315801 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0312328 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0310074 |
| L3MBTL4 | l(3)mbt-like 4 (Drosophila) | -0.0309555 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0305974 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0304522 |
| RPL37A | ribosomal protein L37a | -0.0303596 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0294909 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0292617 |
| NAV3 | neuron navigator 3 | -0.0291327 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0291154 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0290519 |
| LRRC23 | leucine rich repeat containing 23 | -0.0282663 |
| DIP2B | DIP2 disco-interacting protein 2 homolog B (Drosophila) | -0.027921 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0277912 |
| RPS27A | ribosomal protein S27a | -0.0277286 |
| CCND1 | cyclin D1 | -0.0273598 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0271975 |
| CEP112 | centrosomal protein 112kDa | -0.0270072 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0269986 |
| CDH12 | cadherin 12, type 2 (N-cadherin 2) | -0.0269477 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0266774 |
| RPL34 | ribosomal protein L34 | -0.0266452 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0263745 |
| PA2G4 | proliferation-associated 2G4, 38kDa | -0.0263134 |
| CMIP | c-Maf inducing protein | -0.0261809 |
| RPL26 | ribosomal protein L26 | -0.0260357 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.025967 |
| PRDX1 | peroxiredoxin 1 | -0.0258595 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0256542 |
| S100A6 | S100 calcium binding protein A6 | -0.0250715 |
