| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fulvestrant_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0565907 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0378201 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0372403 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0347942 |
| RPTOR | regulatory associated protein of MTOR, complex 1 | 0.0319756 |
| FN1 | fibronectin 1 | 0.0315279 |
| TMF1 | TATA element modulatory factor 1 | 0.0307288 |
| MEF2A | myocyte enhancer factor 2A | 0.0304724 |
| B2M | beta-2-microglobulin | 0.0290353 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0288988 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0277171 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0274626 |
| MCL1 | myeloid cell leukemia 1 | 0.0267964 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0264073 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.024891 |
| CALD1 | caldesmon 1 | 0.0246517 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.024347 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0235977 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0233135 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0228048 |
| HM13 | histocompatibility (minor) 13 | 0.0226041 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.022421 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0223879 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0221168 |
| BRD2 | bromodomain containing 2 | 0.0220076 |
| STC1 | stanniocalcin 1 | 0.0219346 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0219178 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.0208918 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0206118 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0205638 |
| PCBP3 | poly(rC) binding protein 3 | 0.0205602 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0195503 |
| TBCK | TBC1 domain containing kinase | 0.0194285 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0193163 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.0190238 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0189455 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0188374 |
| FKBP1A | FK506 binding protein 1A, 12kDa | 0.0186302 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | 0.0184978 |
| ANO6 | anoctamin 6 | 0.0180755 |
| LOX | lysyl oxidase | 0.0179886 |
| FAM13A | family with sequence similarity 13, member A | 0.017912 |
| HIP1 | huntingtin interacting protein 1 | 0.0179112 |
| VEGFA | vascular endothelial growth factor A | 0.0176008 |
| ARF4 | ADP-ribosylation factor 4 | 0.0173154 |
| VIM | vimentin | 0.0170847 |
| TOR1AIP2 | torsin A interacting protein 2 | 0.0170377 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0167719 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.016702 |
| FLNB | filamin B, beta | 0.0166374 |
| GOLGA2 | golgin A2 | 0.0165062 |
| SMAD3 | SMAD family member 3 | 0.0164016 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0163461 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.01628 |
| ZNF638 | zinc finger protein 638 | 0.0162455 |
| TMEM165 | transmembrane protein 165 | 0.0161834 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0161783 |
| ASPH | aspartate beta-hydroxylase | 0.0160223 |
| HBS1L | HBS1-like translational GTPase | 0.0159968 |
| HDAC9 | histone deacetylase 9 | 0.0159021 |
| RBM39 | RNA binding motif protein 39 | 0.0158765 |
| CCNL1 | cyclin L1 | 0.0158761 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0157903 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0157618 |
| ACAP2 | ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 | 0.0157461 |
| GPC6 | glypican 6 | 0.0157292 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0156657 |
| TPM3 | tropomyosin 3 | 0.015663 |
| ARL5B | ADP-ribosylation factor-like 5B | 0.015616 |
| NAV1 | neuron navigator 1 | 0.0155792 |
| GOLGB1 | golgin B1 | 0.0155561 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0154702 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0154568 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0153871 |
| RNASEH2A | ribonuclease H2, subunit A | 0.0153399 |
| IKBIP | IKBKB interacting protein | 0.0152903 |
| RAI14 | retinoic acid induced 14 | 0.0152324 |
| SLK | STE20-like kinase | 0.015229 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0151863 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0151716 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0150713 |
| KPNA2 | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 0.0150296 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0150143 |
| UBC | ubiquitin C | 0.0149571 |
| LOXL2 | lysyl oxidase-like 2 | 0.0149435 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | 0.01494 |
| ANGPTL4 | angiopoietin-like 4 | 0.0147973 |
| NFIB | nuclear factor I/B | 0.0147209 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.014663 |
| CCNY | cyclin Y | 0.014636 |
| CCDC88A | coiled-coil domain containing 88A | 0.0146044 |
| FLT1 | fms-related tyrosine kinase 1 | 0.014584 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0145348 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0144051 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0142677 |
| NEK1 | NIMA-related kinase 1 | 0.0141708 |
| GDF15 | growth differentiation factor 15 | 0.013908 |
| EP400 | E1A binding protein p400 | 0.0138756 |
| KMT5B | lysine methyltransferase 5B | 0.0138479 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | 0.0138445 |
| Symbol | Name | Standardized Value |
|---|---|---|
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.199093 |
| IGF2 | insulin-like growth factor 2 | -0.103198 |
| FMN1 | formin 1 | -0.101635 |
| LSAMP | limbic system-associated membrane protein | -0.0939437 |
| SYT1 | synaptotagmin I | -0.090558 |
| RPL23 | ribosomal protein L23 | -0.0898761 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.079883 |
| TRIB2 | tribbles pseudokinase 2 | -0.0784436 |
| VCL | vinculin | -0.0733204 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0697092 |
| PTMA | prothymosin, alpha | -0.0694299 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | -0.055244 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0537264 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0535005 |
| MEIS2 | Meis homeobox 2 | -0.0533706 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0524446 |
| AOPEP | aminopeptidase O (putative) | -0.0506782 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0499248 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.049695 |
| RPL19 | ribosomal protein L19 | -0.0495502 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0487489 |
| COL3A1 | collagen, type III, alpha 1 | -0.0481921 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0480152 |
| NREP | neuronal regeneration related protein | -0.0463429 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | -0.0462456 |
| RNF213 | ring finger protein 213 | -0.0461322 |
| PRKCA | protein kinase C, alpha | -0.0458777 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0455879 |
| KLHL13 | kelch-like family member 13 | -0.0455365 |
| RPL38 | ribosomal protein L38 | -0.0451813 |
| RPS24 | ribosomal protein S24 | -0.0447623 |
| COL1A1 | collagen, type I, alpha 1 | -0.0437185 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0430463 |
| DST | dystonin | -0.0420905 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0418793 |
| DPH6 | diphthamine biosynthesis 6 | -0.0418375 |
| ACTG1 | actin gamma 1 | -0.0416964 |
| ANGPT1 | angiopoietin 1 | -0.0416463 |
| TLE4 | transducin-like enhancer of split 4 | -0.0413275 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0409582 |
| MAP1B | microtubule-associated protein 1B | -0.0406396 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0388155 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0387082 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0384381 |
| RPLP1 | ribosomal protein, large, P1 | -0.0381957 |
| RPL34 | ribosomal protein L34 | -0.0376164 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.036788 |
| MED13 | mediator complex subunit 13 | -0.0362884 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0360934 |
| LPIN1 | lipin 1 | -0.0351697 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0351312 |
| AHR | aryl hydrocarbon receptor | -0.0345849 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0338911 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0331414 |
| PTPN13 | protein tyrosine phosphatase, non-receptor type 13 (APO-1/CD95 (Fas)-associated phosphatase) | -0.0328974 |
| AUTS2 | autism susceptibility candidate 2 | -0.032166 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.032088 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0317667 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0316044 |
| MRTFA | myocardin related transcription factor A | -0.031485 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0314502 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0311944 |
| HMBOX1 | homeobox containing 1 | -0.03065 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.030396 |
| RPL31 | ribosomal protein L31 | -0.030345 |
| DNM3 | dynamin 3 | -0.0301199 |
| RPLP0 | ribosomal protein, large, P0 | -0.0300153 |
| RPL37A | ribosomal protein L37a | -0.0296569 |
| FOXK2 | forkhead box K2 | -0.028916 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.02882 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.0285816 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0282935 |
| GLCCI1 | glucocorticoid induced 1 | -0.0280135 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0278956 |
| RPS27A | ribosomal protein S27a | -0.0276565 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0275864 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0274796 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0273621 |
| MSI2 | musashi RNA-binding protein 2 | -0.0273254 |
| HAND2 | heart and neural crest derivatives expressed 2 | -0.0272422 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0272316 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0271949 |
| RPS8 | ribosomal protein S8 | -0.0271588 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0270182 |
| CCDC47 | coiled-coil domain containing 47 | -0.0269766 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0268807 |
| TULP4 | tubby like protein 4 | -0.0268305 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0266021 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0261095 |
| GNAS | GNAS complex locus | -0.0259664 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0259587 |
| RPL35A | ribosomal protein L35a | -0.0259213 |
| DKK2 | dickkopf WNT signaling pathway inhibitor 2 | -0.0259137 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0258892 |
| NRG1 | neuregulin 1 | -0.0256481 |
| ANKRD17 | ankyrin repeat domain 17 | -0.025339 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0253077 |
| ITGA1 | integrin, alpha 1 | -0.0252841 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0251713 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0249153 |
