| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fulvestrant_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| H1-0 | H1.0 linker histone | 0.153705 |
| UBC | ubiquitin C | 0.131908 |
| LMO7 | LIM domain 7 | 0.119004 |
| MACC1 | metastasis associated in colon cancer 1 | 0.109582 |
| EGR1 | early growth response 1 | 0.0932073 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.077604 |
| ANXA2 | annexin A2 | 0.0774011 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0760377 |
| MYO1E | myosin IE | 0.0734643 |
| SDC4 | syndecan 4 | 0.0734044 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0680457 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0671322 |
| EXT1 | exostosin glycosyltransferase 1 | 0.066474 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0664258 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0654677 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0636221 |
| ERBIN | erbb2 interacting protein | 0.0618152 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0582196 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0569261 |
| TXNIP | thioredoxin interacting protein | 0.0569204 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0567098 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0561812 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0557449 |
| AREG | amphiregulin | 0.055672 |
| NDRG1 | N-myc downstream regulated 1 | 0.0556594 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0545568 |
| SQSTM1 | sequestosome 1 | 0.053411 |
| KLF6 | Kruppel-like factor 6 | 0.0531107 |
| ENO1 | enolase 1, (alpha) | 0.0531077 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0523907 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0512283 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0503873 |
| HLA-E | major histocompatibility complex, class I, E | 0.0493613 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.049327 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0468754 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0454762 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0454321 |
| JUN | jun proto-oncogene | 0.0454055 |
| EZR | ezrin | 0.0441273 |
| FNIP1 | folliculin interacting protein 1 | 0.0416405 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.041313 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0412611 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0412401 |
| HLA-A | major histocompatibility complex, class I, A | 0.0406123 |
| SEC24A | SEC24 family member A | 0.0396128 |
| PLIN2 | perilipin 2 | 0.0384692 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.037515 |
| GOLGA2 | golgin A2 | 0.037473 |
| HLA-B | major histocompatibility complex, class I, B | 0.0372565 |
| AHNAK | AHNAK nucleoprotein | 0.0370862 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.035435 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0352085 |
| KIF16B | kinesin family member 16B | 0.0342938 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | 0.034203 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0340783 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0329908 |
| CSTB | cystatin B (stefin B) | 0.0324789 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0324511 |
| TRIB1 | tribbles pseudokinase 1 | 0.0324287 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0314194 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0312157 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0304105 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0302017 |
| TRIM2 | tripartite motif containing 2 | 0.0300534 |
| GOLGB1 | golgin B1 | 0.0298867 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0298208 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0289859 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0287672 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0285113 |
| FDPS | farnesyl diphosphate synthase | 0.028375 |
| SPAG9 | sperm associated antigen 9 | 0.0283659 |
| FTL | ferritin, light polypeptide | 0.0283525 |
| MORF4L2 | mortality factor 4 like 2 | 0.0280733 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0278466 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.027262 |
| MCTP1 | multiple C2 domains, transmembrane 1 | 0.0271614 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0271454 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0269698 |
| DDIT3 | DNA-damage-inducible transcript 3 | 0.0267801 |
| NPSR1 | neuropeptide S receptor 1 | 0.0264631 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.026287 |
| UBAP1 | ubiquitin associated protein 1 | 0.0261252 |
| PGK1 | phosphoglycerate kinase 1 | 0.025784 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.025575 |
| SPATA13 | spermatogenesis associated 13 | 0.0255663 |
| NIPSNAP2 | nipsnap homolog 2 | 0.0252472 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.024946 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0248576 |
| OXSR1 | oxidative stress responsive 1 | 0.0248275 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.024726 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.024602 |
| B3GNT5 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5 | 0.0244705 |
| WDR45B | WD repeat domain 45B | 0.0242552 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0242102 |
| SHOC2 | soc-2 suppressor of clear homolog (C. elegans) | 0.0239572 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.02356 |
| JMJD1C | jumonji domain containing 1C | 0.0235341 |
| ZFP36 | ZFP36 ring finger protein | 0.0233986 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0233374 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0229733 |
| Symbol | Name | Standardized Value |
|---|---|---|
| BTBD9 | BTB (POZ) domain containing 9 | -0.104969 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.082903 |
| RNF43 | ring finger protein 43 | -0.0750944 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0736944 |
| IFNGR1 | interferon gamma receptor 1 | -0.0718202 |
| ARGLU1 | arginine and glutamate rich 1 | -0.0698343 |
| NCKAP5 | NCK-associated protein 5 | -0.0697301 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0691395 |
| RUNX1 | runt-related transcription factor 1 | -0.0678523 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0663006 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.065465 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0642023 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0626464 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.061158 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0602841 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0594646 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0547602 |
| MX1 | MX dynamin-like GTPase 1 | -0.0540642 |
| RNF213 | ring finger protein 213 | -0.0527417 |
| MEIS2 | Meis homeobox 2 | -0.0515073 |
| TXNRD1 | thioredoxin reductase 1 | -0.0495486 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0494063 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0476324 |
| TRERF1 | transcriptional regulating factor 1 | -0.0474236 |
| ADAR | adenosine deaminase, RNA-specific | -0.0473537 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0471264 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0455652 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0449792 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.044906 |
| MAP3K5 | mitogen-activated protein kinase kinase kinase 5 | -0.0438699 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0435309 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0431714 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0423852 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0423306 |
| EPHB2 | EPH receptor B2 | -0.0419784 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0415528 |
| RAD51B | RAD51 paralog B | -0.0411706 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0409317 |
| ASPH | aspartate beta-hydroxylase | -0.0407049 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0407048 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0401146 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0401082 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | -0.0400459 |
| FAT1 | FAT atypical cadherin 1 | -0.0394413 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | -0.0390921 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0384286 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0384238 |
| FOXP1 | forkhead box P1 | -0.0384001 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0374912 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0368258 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0361141 |
| MAN1A1 | mannosidase, alpha, class 1A, member 1 | -0.0358365 |
| SMYD3 | SET and MYND domain containing 3 | -0.0357167 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.035029 |
| RBM26 | RNA binding motif protein 26 | -0.0350127 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0346666 |
| XPO1 | exportin 1 | -0.0342425 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0340524 |
| LCN2 | lipocalin 2 | -0.0338096 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0337531 |
| PRELID2 | PRELI domain containing 2 | -0.03357 |
| ZDHHC20 | zinc finger, DHHC-type containing 20 | -0.032339 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0322714 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0319311 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0318843 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.0316161 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0307474 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0303287 |
| VWA8 | von Willebrand factor A domain containing 8 | -0.030183 |
| ADAM10 | ADAM metallopeptidase domain 10 | -0.0299504 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0298889 |
| MAP7 | microtubule-associated protein 7 | -0.0297042 |
| NF1 | neurofibromin 1 | -0.0291087 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0290263 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0287191 |
| ERP44 | endoplasmic reticulum protein 44 | -0.0286635 |
| EPCAM | epithelial cell adhesion molecule | -0.0279751 |
| METTL15 | methyltransferase like 15 | -0.0279526 |
| IL20RA | interleukin 20 receptor, alpha | -0.0279381 |
| UTRN | utrophin | -0.0276707 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0274981 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0274504 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0272891 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0272044 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0271821 |
| EHF | ets homologous factor | -0.0270208 |
| MAP2K6 | mitogen-activated protein kinase kinase 6 | -0.0270092 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0266539 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0266303 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.026576 |
| PHF3 | PHD finger protein 3 | -0.0264929 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0263591 |
| WWOX | WW domain containing oxidoreductase | -0.026232 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0260705 |
| DST | dystonin | -0.0258614 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0258464 |
| CLTC | clathrin, heavy chain (Hc) | -0.0258086 |
| NEBL | nebulette | -0.0258083 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0254634 |
| PRKCE | protein kinase C, epsilon | -0.0250196 |
