| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fulvestrant_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.224905 |
| COL1A1 | collagen, type I, alpha 1 | 0.155589 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.102442 |
| ATP13A3 | ATPase type 13A3 | 0.0975388 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0912225 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0717219 |
| COL1A2 | collagen, type I, alpha 2 | 0.0676766 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.06387 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0597877 |
| STC1 | stanniocalcin 1 | 0.0537425 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0532615 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0532048 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0522471 |
| POSTN | periostin, osteoblast specific factor | 0.0515429 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0509797 |
| PTK2 | protein tyrosine kinase 2 | 0.0496096 |
| ZNF292 | zinc finger protein 292 | 0.0474035 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0469465 |
| MTSS1 | metastasis suppressor 1 | 0.0454685 |
| SPAG9 | sperm associated antigen 9 | 0.0454587 |
| USP3 | ubiquitin specific peptidase 3 | 0.0430111 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0428007 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0418394 |
| CANX | calnexin | 0.0410291 |
| RNF145 | ring finger protein 145 | 0.0406918 |
| RLF | rearranged L-myc fusion | 0.0401409 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0396296 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0392881 |
| LOXL2 | lysyl oxidase-like 2 | 0.0379718 |
| HAS2 | hyaluronan synthase 2 | 0.0377181 |
| CALU | calumenin | 0.037061 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0366443 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0362593 |
| ANTXR2 | anthrax toxin receptor 2 | 0.0360931 |
| COL4A1 | collagen, type IV, alpha 1 | 0.036042 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0354407 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0353489 |
| CLIC4 | chloride intracellular channel 4 | 0.0346702 |
| FOXJ3 | forkhead box J3 | 0.0341997 |
| PTMA | prothymosin, alpha | 0.0341106 |
| SETD5 | SET domain containing 5 | 0.0340571 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0329195 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0325828 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0323522 |
| COL5A1 | collagen, type V, alpha 1 | 0.0322306 |
| SQLE | squalene epoxidase | 0.0319204 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.031859 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0316936 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0315843 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.0313938 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0312674 |
| SMAD3 | SMAD family member 3 | 0.03123 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0312131 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0311024 |
| COL3A1 | collagen, type III, alpha 1 | 0.0308949 |
| QKI | QKI, KH domain containing, RNA binding | 0.0304878 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0304047 |
| MT1X | metallothionein 1X | 0.0301369 |
| MED13L | mediator complex subunit 13-like | 0.0300932 |
| KLF6 | Kruppel-like factor 6 | 0.0299325 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0299156 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0291079 |
| MRTFA | myocardin related transcription factor A | 0.0290678 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0289377 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.0287314 |
| WRN | Werner syndrome, RecQ helicase-like | 0.0281165 |
| RASA2 | RAS p21 protein activator 2 | 0.0280993 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0279639 |
| SRPK2 | SRSF protein kinase 2 | 0.0276645 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.027382 |
| APP | amyloid beta (A4) precursor protein | 0.0272984 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0272029 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0269436 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0267866 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0267109 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0266834 |
| LAMB1 | laminin, beta 1 | 0.0266402 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0259526 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0256326 |
| ZNF148 | zinc finger protein 148 | 0.0256273 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0255697 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0255128 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | 0.0255122 |
| UBE2G1 | ubiquitin-conjugating enzyme E2G 1 | 0.0253701 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.024932 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0248145 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.0248031 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.0247386 |
| SBF2 | SET binding factor 2 | 0.0242154 |
| HMGA2 | high mobility group AT-hook 2 | 0.0239743 |
| PDE10A | phosphodiesterase 10A | 0.0238888 |
| ANLN | anillin, actin binding protein | 0.0237891 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0233953 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0233149 |
| SMYD3 | SET and MYND domain containing 3 | 0.0232588 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0232175 |
| MAP1B | microtubule-associated protein 1B | 0.0231968 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0230935 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0225768 |
| COG5 | component of oligomeric golgi complex 5 | 0.0224797 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.241599 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.166585 |
| NDRG1 | N-myc downstream regulated 1 | -0.113391 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.107676 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0933014 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0848544 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0698456 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0663503 |
| LDHA | lactate dehydrogenase A | -0.0604576 |
| SQSTM1 | sequestosome 1 | -0.055371 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0551333 |
| ACTG1 | actin gamma 1 | -0.051558 |
| EGR1 | early growth response 1 | -0.0500141 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0479548 |
| RPS8 | ribosomal protein S8 | -0.0478171 |
| HDAC9 | histone deacetylase 9 | -0.0468244 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0453923 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0450215 |
| ENO1 | enolase 1, (alpha) | -0.0433842 |
| RPL12 | ribosomal protein L12 | -0.04193 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0413666 |
| POTEF | POTE ankyrin domain family, member F | -0.0410917 |
| IL6ST | interleukin 6 signal transducer | -0.0401012 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0375493 |
| CNTN5 | contactin 5 | -0.0375313 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.037111 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0365564 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0365447 |
| RPL19 | ribosomal protein L19 | -0.0361393 |
| RACK1 | receptor for activated C kinase 1 | -0.0358539 |
| GOLGB1 | golgin B1 | -0.0358359 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0350464 |
| RPLP0 | ribosomal protein, large, P0 | -0.0348458 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0336838 |
| CA12 | carbonic anhydrase XII | -0.0333323 |
| YBX1 | Y box binding protein 1 | -0.0323995 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0321842 |
| RPL30 | ribosomal protein L30 | -0.0303304 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0297249 |
| IL6 | interleukin 6 | -0.0296307 |
| RPS20 | ribosomal protein S20 | -0.0294121 |
| CDH13 | cadherin 13 | -0.0291702 |
| PRELID2 | PRELI domain containing 2 | -0.0291546 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0290744 |
| RPS2 | ribosomal protein S2 | -0.0283525 |
| VIM | vimentin | -0.0282958 |
| PKM | pyruvate kinase, muscle | -0.0282441 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0279308 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0278883 |
| HMGA1 | high mobility group AT-hook 1 | -0.0276493 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0275703 |
| TMSB10 | thymosin beta 10 | -0.0268561 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0264801 |
| RPL11 | ribosomal protein L11 | -0.0262128 |
| RPL23 | ribosomal protein L23 | -0.0258765 |
| TPI1 | triosephosphate isomerase 1 | -0.0257709 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.02547 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0254261 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0250614 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0246868 |
| NEK10 | NIMA-related kinase 10 | -0.0246195 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0241513 |
| ATXN1 | ataxin 1 | -0.0237609 |
| RPL37A | ribosomal protein L37a | -0.0235689 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0234543 |
| RPS6 | ribosomal protein S6 | -0.0230814 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.022961 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0226735 |
| RND3 | Rho family GTPase 3 | -0.0224858 |
| PGM3 | phosphoglucomutase 3 | -0.0223346 |
| EXOC4 | exocyst complex component 4 | -0.0217244 |
| INHBA | inhibin, beta A | -0.0216224 |
| NAV1 | neuron navigator 1 | -0.0211785 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0209278 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | -0.0209149 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0206416 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0206286 |
| RPS19 | ribosomal protein S19 | -0.0206256 |
| AKR1B1 | aldo-keto reductase family 1, member B1 (aldose reductase) | -0.0205407 |
| RPL9 | ribosomal protein L9 | -0.0205218 |
| RPS16 | ribosomal protein S16 | -0.0203146 |
| B4GALT1 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1 | -0.020301 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0202651 |
| HM13 | histocompatibility (minor) 13 | -0.0201956 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0201495 |
| VCAN | versican | -0.0201257 |
| ANO10 | anoctamin 10 | -0.0200872 |
| RPL7 | ribosomal protein L7 | -0.020085 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0200748 |
| PLSCR1 | phospholipid scramblase 1 | -0.0200531 |
| NCOR2 | nuclear receptor corepressor 2 | -0.0199691 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0197927 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0197138 |
| RIGI | RNA sensor RIG-I | -0.0194402 |
| RPS27A | ribosomal protein S27a | -0.0192636 |
| RPL26 | ribosomal protein L26 | -0.0192035 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0191431 |
| DPYSL2 | dihydropyrimidinase-like 2 | -0.019129 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0190548 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0189765 |
