| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fulvestrant_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FLNB | filamin B, beta | 0.116969 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0735973 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0654189 |
| MSN | moesin | 0.0633165 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0609413 |
| FOXO1 | forkhead box O1 | 0.0557366 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0507858 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0504929 |
| POTEF | POTE ankyrin domain family, member F | 0.0503239 |
| BCL2L1 | BCL2-like 1 | 0.0495309 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0458656 |
| CLU | clusterin | 0.0442523 |
| NRG1 | neuregulin 1 | 0.0440411 |
| NDRG1 | N-myc downstream regulated 1 | 0.0439349 |
| MEF2A | myocyte enhancer factor 2A | 0.0432647 |
| TGM2 | transglutaminase 2 | 0.0413962 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0409191 |
| EZR | ezrin | 0.0406399 |
| ANLN | anillin, actin binding protein | 0.0404275 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0399078 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0367846 |
| TPX2 | TPX2, microtubule-associated | 0.0359531 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.034873 |
| CD44 | CD44 molecule (Indian blood group) | 0.0344981 |
| H1-0 | H1.0 linker histone | 0.0337705 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0325457 |
| RNF145 | ring finger protein 145 | 0.0325384 |
| EFHD2 | EF-hand domain family, member D2 | 0.0321852 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0316509 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0302905 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0301137 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0299833 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0299134 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0296208 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.029457 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0292518 |
| PCDH1 | protocadherin 1 | 0.0291128 |
| ARRDC3 | arrestin domain containing 3 | 0.0290212 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0270771 |
| CMIP | c-Maf inducing protein | 0.0269459 |
| CD99 | CD99 molecule | 0.0266156 |
| ITSN1 | intersectin 1 (SH3 domain protein) | 0.0262413 |
| THOC2 | THO complex 2 | 0.0262162 |
| CYB5R3 | cytochrome b5 reductase 3 | 0.0259354 |
| COPA | coatomer protein complex, subunit alpha | 0.0256558 |
| LNPEP | leucyl/cystinyl aminopeptidase | 0.0253948 |
| PKM | pyruvate kinase, muscle | 0.0250292 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0249374 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0249271 |
| GATA6 | GATA binding protein 6 | 0.024865 |
| OPTN | optineurin | 0.0248113 |
| SLK | STE20-like kinase | 0.0246456 |
| RAB22A | RAB22A, member RAS oncogene family | 0.0244914 |
| SUCO | SUN domain containing ossification factor | 0.0241272 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0240111 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0240045 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0236838 |
| DSTN | destrin (actin depolymerizing factor) | 0.0232533 |
| OGA | O-GlcNAcase | 0.0230467 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.0229152 |
| PTPN1 | protein tyrosine phosphatase, non-receptor type 1 | 0.0227459 |
| TNS4 | tensin 4 | 0.0226096 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | 0.0223799 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0223781 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | 0.0221329 |
| PTEN | phosphatase and tensin homolog | 0.0220333 |
| PDLIM1 | PDZ and LIM domain 1 | 0.0217026 |
| TXNIP | thioredoxin interacting protein | 0.0216518 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0216124 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0215341 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0213454 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | 0.0212794 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0212534 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0212283 |
| GOLGA4 | golgin A4 | 0.0210769 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0210269 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0208927 |
| WASF2 | WAS protein family, member 2 | 0.0208062 |
| PLEKHA1 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 | 0.0208019 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.020601 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0205067 |
| PLAT | plasminogen activator, tissue | 0.0203672 |
| IGF2 | insulin-like growth factor 2 | 0.0201933 |
| SLMAP | sarcolemma associated protein | 0.0201469 |
| SPAG9 | sperm associated antigen 9 | 0.0198754 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0197569 |
| SRP54 | signal recognition particle 54kDa | 0.0196269 |
| CDKN2A | cyclin-dependent kinase inhibitor 2A | 0.0195213 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0195048 |
| YBX3 | Y box binding protein 3 | 0.0193545 |
| PHF20 | PHD finger protein 20 | 0.0193493 |
| NUP58 | nucleoporin 58 | 0.0192797 |
| INSIG2 | insulin induced gene 2 | 0.0192206 |
| RRAS2 | related RAS viral (r-ras) oncogene homolog 2 | 0.0191762 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | 0.0191746 |
| FNBP4 | formin binding protein 4 | 0.0191471 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0190754 |
| PLK2 | polo-like kinase 2 | 0.0190135 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0189735 |
| EPHA2 | EPH receptor A2 | 0.0189034 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.319705 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.174319 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.158377 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.133134 |
| INTS6 | integrator complex subunit 6 | -0.112268 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0991774 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0881013 |
| MTSS1 | metastasis suppressor 1 | -0.0879904 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0879748 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0876284 |
| RPS8 | ribosomal protein S8 | -0.0775284 |
| ST3GAL6 | ST3 beta-galactoside alpha-2,3-sialyltransferase 6 | -0.0703163 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0683083 |
| ASPH | aspartate beta-hydroxylase | -0.0673246 |
| EXT1 | exostosin glycosyltransferase 1 | -0.065432 |
| LAMC2 | laminin, gamma 2 | -0.0634093 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0632013 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0610675 |
| VCL | vinculin | -0.0607404 |
| SQSTM1 | sequestosome 1 | -0.0603829 |
| SULF2 | sulfatase 2 | -0.0602372 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0599435 |
| AHNAK | AHNAK nucleoprotein | -0.0598549 |
| S100A10 | S100 calcium binding protein A10 | -0.0593487 |
| TMSB10 | thymosin beta 10 | -0.0576005 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0569268 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0566984 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0558924 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.052888 |
| RPS24 | ribosomal protein S24 | -0.050725 |
| NAV2 | neuron navigator 2 | -0.0503811 |
| RPS12 | ribosomal protein S12 | -0.0491138 |
| RIGI | RNA sensor RIG-I | -0.0484553 |
| STC1 | stanniocalcin 1 | -0.0482814 |
| RPL34 | ribosomal protein L34 | -0.0480612 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0476574 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0463573 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0456131 |
| RPS25 | ribosomal protein S25 | -0.0454654 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.045235 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.044035 |
| LMO7 | LIM domain 7 | -0.0427604 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0417287 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0416412 |
| RPL37 | ribosomal protein L37 | -0.0416267 |
| PALLD | palladin, cytoskeletal associated protein | -0.0411188 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0405182 |
| HLA-B | major histocompatibility complex, class I, B | -0.0403722 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0397192 |
| LDHA | lactate dehydrogenase A | -0.0393461 |
| RPS21 | ribosomal protein S21 | -0.0389992 |
| PRSS23 | protease, serine, 23 | -0.0385144 |
| RPL23 | ribosomal protein L23 | -0.0384082 |
| RPL12 | ribosomal protein L12 | -0.0380487 |
| RPL11 | ribosomal protein L11 | -0.0377679 |
| MTAP | methylthioadenosine phosphorylase | -0.0374086 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0372387 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0368971 |
| HMGA2 | high mobility group AT-hook 2 | -0.0368097 |
| RPS6 | ribosomal protein S6 | -0.0367268 |
| CSMD2 | CUB and Sushi multiple domains 2 | -0.0366082 |
| RPS3 | ribosomal protein S3 | -0.0364827 |
| PLEC | plectin | -0.0359733 |
| RPL26 | ribosomal protein L26 | -0.0359181 |
| RPLP0 | ribosomal protein, large, P0 | -0.0349216 |
| RPL37A | ribosomal protein L37a | -0.0349078 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.034863 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0345711 |
| ANO1 | anoctamin 1, calcium activated chloride channel | -0.0345028 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0341591 |
| RPLP2 | ribosomal protein, large, P2 | -0.034151 |
| DENND1A | DENN/MADD domain containing 1A | -0.0341291 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0339357 |
| RCOR1 | REST corepressor 1 | -0.0337558 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0332537 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0329488 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.032492 |
| ARF1 | ADP-ribosylation factor 1 | -0.0320216 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.031524 |
| ANXA2 | annexin A2 | -0.031292 |
| CLIC4 | chloride intracellular channel 4 | -0.0310696 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0305661 |
| SMYD3 | SET and MYND domain containing 3 | -0.030413 |
| AHNAK2 | AHNAK nucleoprotein 2 | -0.0302881 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0301799 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0301582 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0300814 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0300625 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0298978 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | -0.029695 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0288734 |
| EFNA5 | ephrin-A5 | -0.0287869 |
| RPLP1 | ribosomal protein, large, P1 | -0.0286554 |
| RPL35A | ribosomal protein L35a | -0.0284817 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0283567 |
| CDK13 | cyclin-dependent kinase 13 | -0.0280982 |
| RAI14 | retinoic acid induced 14 | -0.0278268 |
| SLC12A6 | solute carrier family 12 (potassium/chloride transporter), member 6 | -0.0277219 |
| THBD | thrombomodulin | -0.0277129 |
| RPS27A | ribosomal protein S27a | -0.0276086 |
