| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fulvestrant_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| POTEF | POTE ankyrin domain family, member F | 0.0541832 |
| LMO7 | LIM domain 7 | 0.0461678 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0368746 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0368532 |
| VEGFA | vascular endothelial growth factor A | 0.0358658 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.033497 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0304219 |
| UBC | ubiquitin C | 0.0276795 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0255521 |
| VMP1 | vacuole membrane protein 1 | 0.0243772 |
| ANXA1 | annexin A1 | 0.0237105 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0229357 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0227118 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0211379 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0210067 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0206908 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0203224 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.017956 |
| PCDH1 | protocadherin 1 | 0.0177787 |
| GDA | guanine deaminase | 0.0170796 |
| SETD5 | SET domain containing 5 | 0.0169111 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0168608 |
| HDAC9 | histone deacetylase 9 | 0.0163045 |
| TNIK | TRAF2 and NCK interacting kinase | 0.0161398 |
| BRD2 | bromodomain containing 2 | 0.015765 |
| MYO1E | myosin IE | 0.0151038 |
| CLDN7 | claudin 7 | 0.0150525 |
| SLC9A3R1 | solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 1 | 0.0150368 |
| PCBP2 | poly(rC) binding protein 2 | 0.0149724 |
| CLDN4 | claudin 4 | 0.0149552 |
| RNASE1 | ribonuclease, RNase A family, 1 (pancreatic) | 0.0148517 |
| MUC1 | mucin 1, cell surface associated | 0.0145562 |
| CDK19 | cyclin-dependent kinase 19 | 0.0145445 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | 0.0143475 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0140356 |
| TXNIP | thioredoxin interacting protein | 0.013683 |
| INTS6 | integrator complex subunit 6 | 0.0135829 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0135314 |
| EGR1 | early growth response 1 | 0.0134924 |
| LGALS3BP | lectin, galactoside-binding, soluble, 3 binding protein | 0.0133889 |
| TMF1 | TATA element modulatory factor 1 | 0.0132484 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0131959 |
| LYZ | lysozyme | 0.0131789 |
| CCNL1 | cyclin L1 | 0.0131618 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0124593 |
| RNPS1 | RNA binding protein S1, serine-rich domain | 0.0121727 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0121074 |
| ZFP36 | ZFP36 ring finger protein | 0.0120055 |
| NXPH4 | neurexophilin 4 | 0.0119495 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0118585 |
| FNIP1 | folliculin interacting protein 1 | 0.0118191 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0113227 |
| RPL4 | ribosomal protein L4 | 0.0111676 |
| TJP1 | tight junction protein 1 | 0.0111383 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.0111301 |
| LIPH | lipase, member H | 0.0111261 |
| COG6 | component of oligomeric golgi complex 6 | 0.0109372 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0109037 |
| MYOF | myoferlin | 0.010773 |
| CD24 | CD24 molecule | 0.0107231 |
| RPL21 | ribosomal protein L21 | 0.0106245 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0106228 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0105803 |
| DHFR | dihydrofolate reductase | 0.0104623 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0104008 |
| EDN1 | endothelin 1 | 0.0102676 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0101578 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.010082 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.00998835 |
| FAM13A | family with sequence similarity 13, member A | 0.0099755 |
| PHLPP1 | PH domain and leucine rich repeat protein phosphatase 1 | 0.00997053 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.00985909 |
| TTYH3 | tweety family member 3 | 0.00985498 |
| DST | dystonin | 0.009853 |
| ADAM32 | ADAM metallopeptidase domain 32 | 0.00984278 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.00981511 |
| SRP54 | signal recognition particle 54kDa | 0.00980114 |
| RAB7A | RAB7A, member RAS oncogene family | 0.00967063 |
| SQLE | squalene epoxidase | 0.00949785 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.00936928 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.00929616 |
| LATS2 | large tumor suppressor kinase 2 | 0.00912635 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.00911118 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.00908124 |
| SLTM | SAFB-like, transcription modulator | 0.00907578 |
| LRP6 | low density lipoprotein receptor-related protein 6 | 0.00905028 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00895403 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.00890276 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.00889227 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.00887034 |
| MUC3B | mucin 3B, cell surface associated | 0.00882461 |
| SYNJ2 | synaptojanin 2 | 0.00877831 |
| SLC7A5 | solute carrier family 7 (amino acid transporter light chain, L system), member 5 | 0.0087609 |
| ATF7IP | activating transcription factor 7 interacting protein | 0.00870519 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.00865687 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0086132 |
| MYEOV | myeloma overexpressed | 0.00851968 |
| NCOR2 | nuclear receptor corepressor 2 | 0.00841977 |
| ADAM28 | ADAM metallopeptidase domain 28 | 0.00835255 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.00826031 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.299712 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.293583 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.141989 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.116245 |
| TMSB10 | thymosin beta 10 | -0.107442 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0992853 |
| KRT18 | keratin 18, type I | -0.0909147 |
| PTMA | prothymosin, alpha | -0.0865966 |
| AGR2 | anterior gradient 2 | -0.0839734 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0707707 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0700319 |
| KRT8 | keratin 8, type II | -0.0685638 |
| CANX | calnexin | -0.0649019 |
| RPL35A | ribosomal protein L35a | -0.0640493 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0637845 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.061291 |
| PGK1 | phosphoglycerate kinase 1 | -0.0590913 |
| ANXA2 | annexin A2 | -0.0587956 |
| TMSB4X | thymosin beta 4, X-linked | -0.0508069 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0491326 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0457731 |
| TES | testin LIM domain protein | -0.0456456 |
| ACTN4 | actinin, alpha 4 | -0.0454062 |
| TMEM123 | transmembrane protein 123 | -0.0443822 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0433173 |
| RPL23 | ribosomal protein L23 | -0.043187 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0431139 |
| HLA-C | major histocompatibility complex, class I, C | -0.042049 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.041742 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0410989 |
| AHNAK | AHNAK nucleoprotein | -0.0403678 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0402365 |
| RPL26 | ribosomal protein L26 | -0.0398448 |
| EPCAM | epithelial cell adhesion molecule | -0.0390926 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0390558 |
| RBM39 | RNA binding motif protein 39 | -0.0380536 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0380223 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0377889 |
| EZR | ezrin | -0.0367627 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0362076 |
| RPS24 | ribosomal protein S24 | -0.0361916 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0354811 |
| RPS21 | ribosomal protein S21 | -0.0348608 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | -0.0348177 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0334849 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0326918 |
| RPLP1 | ribosomal protein, large, P1 | -0.0324405 |
| KPNB1 | karyopherin (importin) beta 1 | -0.03145 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0313963 |
| S100A6 | S100 calcium binding protein A6 | -0.0310515 |
| TFRC | transferrin receptor | -0.0309291 |
| RRBP1 | ribosome binding protein 1 | -0.0307376 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0292298 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0289285 |
| ARF1 | ADP-ribosylation factor 1 | -0.0288286 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0287094 |
| RPS3 | ribosomal protein S3 | -0.0285255 |
| S100A10 | S100 calcium binding protein A10 | -0.0284482 |
| RPL12 | ribosomal protein L12 | -0.0276396 |
| EMP1 | epithelial membrane protein 1 | -0.0273969 |
| RPL38 | ribosomal protein L38 | -0.0273786 |
| DEK | DEK proto-oncogene | -0.0273298 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0271422 |
| ARCN1 | archain 1 | -0.0266468 |
| ANLN | anillin, actin binding protein | -0.0264133 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0264095 |
| GNAS | GNAS complex locus | -0.0263386 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0262847 |
| TXNRD1 | thioredoxin reductase 1 | -0.0262411 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0257029 |
| RPL34 | ribosomal protein L34 | -0.0253306 |
| CLTC | clathrin, heavy chain (Hc) | -0.0251988 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0251123 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0250632 |
| CCDC47 | coiled-coil domain containing 47 | -0.0244691 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0242877 |
| RPS25 | ribosomal protein S25 | -0.0240915 |
| CALR | calreticulin | -0.024048 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | -0.0237934 |
| WDR45B | WD repeat domain 45B | -0.0234087 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0233743 |
| RPLP0 | ribosomal protein, large, P0 | -0.0232274 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0230954 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0230824 |
| HM13 | histocompatibility (minor) 13 | -0.0230388 |
| CBX3 | chromobox homolog 3 | -0.023012 |
| HMGB1 | high mobility group box 1 | -0.0229939 |
| ATF5 | activating transcription factor 5 | -0.0227529 |
| RPS4X | ribosomal protein S4, X-linked | -0.0226557 |
| ACTG1 | actin gamma 1 | -0.0224159 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0223237 |
| CALU | calumenin | -0.0223013 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0222462 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0221816 |
| ATXN1 | ataxin 1 | -0.0218815 |
| NPSR1 | neuropeptide S receptor 1 | -0.0217371 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.021649 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0216045 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0212554 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0211455 |
