| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fulvestrant_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TXNRD1 | thioredoxin reductase 1 | 0.1407 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0836196 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0769779 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0703748 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0650577 |
| RTN4 | reticulon 4 | 0.0629059 |
| RAI1 | retinoic acid induced 1 | 0.0609564 |
| EZR | ezrin | 0.0571707 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0551557 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0548505 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0546913 |
| JMJD1C | jumonji domain containing 1C | 0.0495202 |
| TMEM41B | transmembrane protein 41B | 0.0489139 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0421603 |
| CENPF | centromere protein F, 350/400kDa | 0.0420449 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0417387 |
| RPL35A | ribosomal protein L35a | 0.0414638 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0408395 |
| SPAG9 | sperm associated antigen 9 | 0.0404702 |
| MKI67 | marker of proliferation Ki-67 | 0.0389229 |
| FLNB | filamin B, beta | 0.0385473 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0383591 |
| CAPRIN2 | caprin family member 2 | 0.0377433 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.037289 |
| NUP58 | nucleoporin 58 | 0.0370981 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0370108 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.036954 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0360084 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | 0.0358888 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0347487 |
| TPX2 | TPX2, microtubule-associated | 0.0343461 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0335484 |
| CKAP5 | cytoskeleton associated protein 5 | 0.033539 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0333848 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0332007 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0317023 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0316297 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0308268 |
| UBC | ubiquitin C | 0.0305364 |
| KIF5B | kinesin family member 5B | 0.0300142 |
| ECT2 | epithelial cell transforming 2 | 0.0299478 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0299205 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0297449 |
| PTMA | prothymosin, alpha | 0.0294756 |
| ATP13A3 | ATPase type 13A3 | 0.0291177 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0287887 |
| RBM39 | RNA binding motif protein 39 | 0.0278489 |
| PHIP | pleckstrin homology domain interacting protein | 0.027794 |
| MATR3 | matrin 3 | 0.0277195 |
| TOP1 | topoisomerase (DNA) I | 0.0275567 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0274844 |
| SET | SET nuclear proto-oncogene | 0.0270688 |
| RNF145 | ring finger protein 145 | 0.026894 |
| OGA | O-GlcNAcase | 0.026865 |
| CEP170 | centrosomal protein 170kDa | 0.0267788 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0267033 |
| SBF2 | SET binding factor 2 | 0.02642 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0260772 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0260695 |
| WDR45B | WD repeat domain 45B | 0.0258954 |
| DENND5A | DENN/MADD domain containing 5A | 0.0257905 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0252727 |
| ANLN | anillin, actin binding protein | 0.0252492 |
| ARHGAP29 | Rho GTPase activating protein 29 | 0.0250261 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0249718 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0249114 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | 0.024871 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0247653 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0246662 |
| FOXJ3 | forkhead box J3 | 0.0242304 |
| PUM2 | pumilio RNA-binding family member 2 | 0.0240578 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0238379 |
| TRA2B | transformer 2 beta homolog (Drosophila) | 0.0236952 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0236623 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0235872 |
| MCL1 | myeloid cell leukemia 1 | 0.0235296 |
| UPP1 | uridine phosphorylase 1 | 0.0233872 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0233505 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0232515 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0231689 |
| KIF14 | kinesin family member 14 | 0.0231623 |
| RLF | rearranged L-myc fusion | 0.0231431 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0231089 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | 0.0231052 |
| USP34 | ubiquitin specific peptidase 34 | 0.0230179 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | 0.022875 |
| ESCO1 | establishment of sister chromatid cohesion N-acetyltransferase 1 | 0.0228427 |
| FUBP1 | far upstream element (FUSE) binding protein 1 | 0.022757 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0225683 |
| QKI | QKI, KH domain containing, RNA binding | 0.0225329 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.0225213 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0223584 |
| PGK1 | phosphoglycerate kinase 1 | 0.0223392 |
| ANGPTL4 | angiopoietin-like 4 | 0.022146 |
| ERBIN | erbb2 interacting protein | 0.0220548 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0218499 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0218172 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0215216 |
| TNFRSF10D | tumor necrosis factor receptor superfamily, member 10d, decoy with truncated death domain | 0.0213769 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0213697 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TP63 | tumor protein p63 | -0.232106 |
| CD44 | CD44 molecule (Indian blood group) | -0.16541 |
| CADM2 | cell adhesion molecule 2 | -0.163502 |
| DST | dystonin | -0.154851 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.154588 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.140847 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.139119 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.138865 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.103226 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0943259 |
| TMSB10 | thymosin beta 10 | -0.0893623 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0877996 |
| TNS3 | tensin 3 | -0.0800499 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0796475 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0772647 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0741955 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0738961 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0693628 |
| EHBP1 | EH domain binding protein 1 | -0.0693303 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0683732 |
| RNF213 | ring finger protein 213 | -0.0638698 |
| RAD51B | RAD51 paralog B | -0.0627249 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.062097 |
| PDE10A | phosphodiesterase 10A | -0.0620776 |
| EFNA5 | ephrin-A5 | -0.0620591 |
| EPHA4 | EPH receptor A4 | -0.0615433 |
| PRELID2 | PRELI domain containing 2 | -0.0609164 |
| RIGI | RNA sensor RIG-I | -0.0605548 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0590285 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0580558 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.057202 |
| HLA-B | major histocompatibility complex, class I, B | -0.0552443 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0535174 |
| EXOC4 | exocyst complex component 4 | -0.0529851 |
| PLSCR1 | phospholipid scramblase 1 | -0.0528407 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0515406 |
| MT2A | metallothionein 2A | -0.0499036 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0474395 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0470347 |
| DNER | delta/notch-like EGF repeat containing | -0.0462228 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0457495 |
| RPS8 | ribosomal protein S8 | -0.0457454 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.044434 |
| TMSB4X | thymosin beta 4, X-linked | -0.044082 |
| VCL | vinculin | -0.0434354 |
| HDAC9 | histone deacetylase 9 | -0.043026 |
| RUNX1 | runt-related transcription factor 1 | -0.0428061 |
| MYOF | myoferlin | -0.0427644 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0423315 |
| RPL23 | ribosomal protein L23 | -0.0422847 |
| EGFR | epidermal growth factor receptor | -0.0416929 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0409783 |
| SP100 | SP100 nuclear antigen | -0.0409735 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0399951 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0377805 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0364944 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0354785 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0352279 |
| COL5A2 | collagen, type V, alpha 2 | -0.0341057 |
| ECE1 | endothelin converting enzyme 1 | -0.0338331 |
| CFLAR | CASP8 and FADD-like apoptosis regulator | -0.0325363 |
| RAB27B | RAB27B, member RAS oncogene family | -0.0324814 |
| DPH6 | diphthamine biosynthesis 6 | -0.0321835 |
| NR2F1 | nuclear receptor subfamily 2, group F, member 1 | -0.0319395 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0315797 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0309978 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0309952 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0299786 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0296583 |
| ENO1 | enolase 1, (alpha) | -0.0296539 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0290206 |
| RPL12 | ribosomal protein L12 | -0.0288274 |
| PMP22 | peripheral myelin protein 22 | -0.0284927 |
| CUX1 | cut-like homeobox 1 | -0.0278586 |
| TGM2 | transglutaminase 2 | -0.0275012 |
| MT1E | metallothionein 1E | -0.0267126 |
| SLC39A10 | solute carrier family 39 (zinc transporter), member 10 | -0.0265389 |
| RACK1 | receptor for activated C kinase 1 | -0.0261138 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0260788 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0260234 |
| DENND1A | DENN/MADD domain containing 1A | -0.0258498 |
| RPL35 | ribosomal protein L35 | -0.0256859 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0255486 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0251975 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0251733 |
| NEK10 | NIMA-related kinase 10 | -0.0250071 |
| SMYD3 | SET and MYND domain containing 3 | -0.0248525 |
| TPRG1 | tumor protein p63 regulated 1 | -0.024423 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.024041 |
| DTX3L | deltex 3 like, E3 ubiquitin ligase | -0.0238201 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0235335 |
| IFIT1 | interferon-induced protein with tetratricopeptide repeats 1 | -0.0234559 |
| AEBP2 | AE binding protein 2 | -0.0233639 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0229832 |
| TMEM123 | transmembrane protein 123 | -0.0229235 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0229012 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0228972 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0228451 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0222663 |
| RPS19 | ribosomal protein S19 | -0.0222268 |
