| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fulvestrant_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.0303134 |
| H1-0 | H1.0 linker histone | 0.0141568 |
| FRY | furry homolog (Drosophila) | 0.0086828 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.00634611 |
| FAM13A | family with sequence similarity 13, member A | 0.00618644 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | 0.00558441 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0053238 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.00526437 |
| ZBTB25 | zinc finger and BTB domain containing 25 | 0.00525224 |
| PER2 | period circadian clock 2 | 0.00507019 |
| KDM3B | lysine (K)-specific demethylase 3B | 0.00486798 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.00441523 |
| LRRC8C | leucine rich repeat containing 8 family, member C | 0.00435975 |
| TSC22D2 | TSC22 domain family, member 2 | 0.00430398 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.00418218 |
| DHFR | dihydrofolate reductase | 0.00415517 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.00401813 |
| GRB10 | growth factor receptor-bound protein 10 | 0.00396093 |
| SEMA6A | sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A | 0.00393916 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.00392616 |
| FA2H | fatty acid 2-hydroxylase | 0.00385755 |
| SCARB1 | scavenger receptor class B, member 1 | 0.00384683 |
| BLZF1 | basic leucine zipper nuclear factor 1 | 0.00381591 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.00365594 |
| LRRC23 | leucine rich repeat containing 23 | 0.00359185 |
| SCNN1G | sodium channel, non voltage gated 1 gamma subunit | 0.00353998 |
| TRIM72 | tripartite motif containing 72, E3 ubiquitin protein ligase | 0.00352566 |
| PEX19 | peroxisomal biogenesis factor 19 | 0.00347881 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | 0.00341935 |
| ADAM20 | ADAM metallopeptidase domain 20 | 0.00340917 |
| HMGA2 | high mobility group AT-hook 2 | 0.0034074 |
| CCNL1 | cyclin L1 | 0.00339501 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.00339202 |
| DNER | delta/notch-like EGF repeat containing | 0.00334095 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | 0.00327407 |
| PKIA | protein kinase (cAMP-dependent, catalytic) inhibitor alpha | 0.00313557 |
| LDHC | lactate dehydrogenase C | 0.00312991 |
| CYP51A1 | cytochrome P450, family 51, subfamily A, polypeptide 1 | 0.00312898 |
| NRXN3 | neurexin 3 | 0.00312491 |
| BCL6 | B-cell CLL/lymphoma 6 | 0.00312016 |
| KRT86 | keratin 86, type II | 0.00310867 |
| RNF217 | ring finger protein 217 | 0.00309806 |
| RNF144B | ring finger protein 144B | 0.00309507 |
| ZC3H12A | zinc finger CCCH-type containing 12A | 0.00307082 |
| TMEM45B | transmembrane protein 45B | 0.00302067 |
| HIVEP1 | human immunodeficiency virus type I enhancer binding protein 1 | 0.00300786 |
| BAG5 | BCL2-associated athanogene 5 | 0.00300352 |
| CKS2 | CDC28 protein kinase regulatory subunit 2 | 0.00298502 |
| MYOCOS | myocilin opposite strand | 0.00298206 |
| STAT4 | signal transducer and activator of transcription 4 | 0.00296429 |
| BAG6 | BCL2-associated athanogene 6 | 0.00295513 |
| CRYM | crystallin, mu | 0.00289095 |
| RDH10 | retinol dehydrogenase 10 (all-trans) | 0.00287854 |
| GTF2IRD2B | GTF2I repeat domain containing 2B | 0.00286174 |
| SNX31 | sorting nexin 31 | 0.00285868 |
| FAM117B | family with sequence similarity 117, member B | 0.0028505 |
| DNHD1 | dynein heavy chain domain 1 | 0.00284679 |
| GCAT | glycine C-acetyltransferase | 0.00283884 |
| NBPF15 | neuroblastoma breakpoint family, member 15 | 0.00283364 |
| ARL9 | ADP-ribosylation factor-like 9 | 0.0028318 |
| GRAMD2A | GRAM domain containing 2A | 0.00281383 |
| ZBED6 | zinc finger, BED-type containing 6 | 0.00280645 |
| PLSCR2 | phospholipid scramblase 2 | 0.00279672 |
| S100A8 | S100 calcium binding protein A8 | 0.00279333 |
| TOB2 | transducer of ERBB2, 2 | 0.00278137 |
| KIAA0753 | KIAA0753 | 0.00277869 |
| CLMP | CXADR-like membrane protein | 0.00277555 |
| ANTXR2 | anthrax toxin receptor 2 | 0.00276102 |
| CUL9 | cullin 9 | 0.00275969 |
| XG | Xg blood group | 0.00274579 |
| TCEANC | transcription elongation factor A (SII) N-terminal and central domain containing | 0.00274543 |
| CCDC18 | coiled-coil domain containing 18 | 0.00272837 |
| FPGT-TNNI3K | FPGT-TNNI3K readthrough | 0.00272126 |
| KCNH5 | potassium channel, voltage gated eag related subfamily H, member 5 | 0.0026754 |
| CD109 | CD109 molecule | 0.00267116 |
| ZDHHC6 | zinc finger, DHHC-type containing 6 | 0.00267005 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.00263895 |
| DHCR7 | 7-dehydrocholesterol reductase | 0.00262589 |
| TRNAU1AP | tRNA selenocysteine 1 associated protein 1 | 0.0026247 |
| CCDC146 | coiled-coil domain containing 146 | 0.00262013 |
| TICAM1 | toll-like receptor adaptor molecule 1 | 0.00261817 |
| HAL | histidine ammonia-lyase | 0.00260891 |
| TRIM3 | tripartite motif containing 3 | 0.0025922 |
| PRPSAP1 | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 0.00258674 |
| GPR137C | G protein-coupled receptor 137C | 0.00258639 |
| ANO3 | anoctamin 3 | 0.0025862 |
| SSPN | sarcospan | 0.00258325 |
| TLE4 | transducin-like enhancer of split 4 | 0.00258235 |
| SLC6A8 | solute carrier family 6 (neurotransmitter transporter), member 8 | 0.00257488 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.00257186 |
| HAP1 | huntingtin-associated protein 1 | 0.00256671 |
| PPP1R13L | protein phosphatase 1, regulatory subunit 13 like | 0.00256026 |
| RING1 | ring finger protein 1 | 0.00255657 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.00255562 |
| HS6ST3 | heparan sulfate 6-O-sulfotransferase 3 | 0.00255424 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.00254815 |
| LSM11 | LSM11, U7 small nuclear RNA associated | 0.00254732 |
| PHKG2 | phosphorylase kinase, gamma 2 (testis) | 0.00254469 |
| AFF3 | AF4/FMR2 family, member 3 | 0.00254097 |
| C1S | complement component 1, s subcomponent | 0.00252847 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.221897 |
| TXNRD1 | thioredoxin reductase 1 | -0.163421 |
| ASPH | aspartate beta-hydroxylase | -0.142197 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.115015 |
| UBC | ubiquitin C | -0.114814 |
| TMSB10 | thymosin beta 10 | -0.100939 |
| ENO1 | enolase 1, (alpha) | -0.0787071 |
| PKM | pyruvate kinase, muscle | -0.077906 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.076961 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0716012 |
| EGFR | epidermal growth factor receptor | -0.069066 |
| LAMC2 | laminin, gamma 2 | -0.0638929 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0617011 |
| LDHA | lactate dehydrogenase A | -0.0611326 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0603595 |
| PTMA | prothymosin, alpha | -0.0577302 |
| RPS27A | ribosomal protein S27a | -0.0577001 |
| MCL1 | myeloid cell leukemia 1 | -0.051868 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0510513 |
| RPS3 | ribosomal protein S3 | -0.0478785 |
| PCBP2 | poly(rC) binding protein 2 | -0.0465761 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0458762 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0452511 |
| GRAMD1B | GRAM domain containing 1B | -0.0430873 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0420781 |
| ACTG1 | actin gamma 1 | -0.0413149 |
| CANX | calnexin | -0.0408135 |
| S100A10 | S100 calcium binding protein A10 | -0.0405901 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0403299 |
| ANXA2 | annexin A2 | -0.0402188 |
| PGK1 | phosphoglycerate kinase 1 | -0.0400209 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0383197 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0368142 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0363385 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.034732 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0346237 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0341288 |
| FTL | ferritin, light polypeptide | -0.0338412 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0324422 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0323534 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0323032 |
| TES | testin LIM domain protein | -0.0322811 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0312191 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0311218 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0304616 |
| HDLBP | high density lipoprotein binding protein | -0.0303424 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0302259 |
| AHNAK | AHNAK nucleoprotein | -0.0297401 |
| KRT18 | keratin 18, type I | -0.0297092 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0295192 |
| RPS24 | ribosomal protein S24 | -0.0290375 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0289292 |
| MYOF | myoferlin | -0.0286442 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0282073 |
| TOP1 | topoisomerase (DNA) I | -0.0280637 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.027838 |
| SEC61G | Sec61 gamma subunit | -0.0277831 |
| B2M | beta-2-microglobulin | -0.0274765 |
| KRT7 | keratin 7, type II | -0.0273518 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0269547 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0263294 |
| CPE | carboxypeptidase E | -0.0263107 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0257678 |
| FNDC3B | fibronectin type III domain containing 3B | -0.025705 |
| SLTM | SAFB-like, transcription modulator | -0.0256933 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | -0.0254684 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0253482 |
| RAB10 | RAB10, member RAS oncogene family | -0.0253139 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0252052 |
| RPS25 | ribosomal protein S25 | -0.0251148 |
| SLC38A1 | solute carrier family 38, member 1 | -0.025094 |
| STC1 | stanniocalcin 1 | -0.0250158 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0249607 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0249517 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0249334 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0246397 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | -0.0245848 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0244825 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | -0.0244267 |
| USP34 | ubiquitin specific peptidase 34 | -0.0243949 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0243592 |
| LAMB3 | laminin, beta 3 | -0.0240193 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0238735 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0234083 |
| RPL37A | ribosomal protein L37a | -0.0232834 |
| SMAD3 | SMAD family member 3 | -0.0232283 |
| LMO7 | LIM domain 7 | -0.0230888 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0230668 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0229304 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0226567 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0226283 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0221443 |
| ZC3H11A | zinc finger CCCH-type containing 11A | -0.0221411 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0217602 |
| SPAG9 | sperm associated antigen 9 | -0.0215552 |
| CALR | calreticulin | -0.0215267 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0214909 |
| APP | amyloid beta (A4) precursor protein | -0.0213892 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0211695 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0210716 |
