| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fulvestrant_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.106404 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.101131 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0964335 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0895218 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0890193 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0880377 |
| STC1 | stanniocalcin 1 | 0.068104 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0637836 |
| GLCCI1 | glucocorticoid induced 1 | 0.0627113 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0588184 |
| MTSS1 | metastasis suppressor 1 | 0.056289 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | 0.054957 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0522468 |
| MEF2A | myocyte enhancer factor 2A | 0.0503683 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0479345 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0477588 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0471333 |
| USP34 | ubiquitin specific peptidase 34 | 0.0459368 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0441547 |
| HMGA2 | high mobility group AT-hook 2 | 0.0433655 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0412622 |
| DPYD | dihydropyrimidine dehydrogenase | 0.0399176 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0398936 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0398075 |
| JMJD1C | jumonji domain containing 1C | 0.0397931 |
| CDH13 | cadherin 13 | 0.0390553 |
| VIM | vimentin | 0.0363646 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0359155 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.035281 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0347947 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.033982 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0335472 |
| VEGFA | vascular endothelial growth factor A | 0.0313358 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0309357 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 0.0304157 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0299752 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0299452 |
| SETD5 | SET domain containing 5 | 0.0298056 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0295632 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0290292 |
| VMP1 | vacuole membrane protein 1 | 0.0287549 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | 0.0285055 |
| DTNA | dystrobrevin, alpha | 0.0283697 |
| LOX | lysyl oxidase | 0.0282863 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0282627 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0281608 |
| AADAC | arylacetamide deacetylase | 0.0280932 |
| CDK14 | cyclin-dependent kinase 14 | 0.0280931 |
| CLMP | CXADR-like membrane protein | 0.0279962 |
| PRRX1 | paired related homeobox 1 | 0.0277065 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0274987 |
| IL1B | interleukin 1, beta | 0.0274563 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0270004 |
| NAV1 | neuron navigator 1 | 0.0269081 |
| SNX9 | sorting nexin 9 | 0.0268933 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.026845 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0263746 |
| MSRB3 | methionine sulfoxide reductase B3 | 0.0262051 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0260686 |
| PLIN2 | perilipin 2 | 0.0260662 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0259972 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0258511 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | 0.0253374 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0253227 |
| NLK | nemo-like kinase | 0.0252036 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0251161 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0250143 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0249956 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0249753 |
| RASAL2 | RAS protein activator like 2 | 0.0248943 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0248244 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.024603 |
| NOTCH2 | notch 2 | 0.0245363 |
| NRG1 | neuregulin 1 | 0.0244491 |
| RAI14 | retinoic acid induced 14 | 0.0241772 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0237553 |
| DNER | delta/notch-like EGF repeat containing | 0.0237423 |
| NUMB | numb homolog (Drosophila) | 0.0237154 |
| ATF7 | activating transcription factor 7 | 0.0233496 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0229558 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0228755 |
| S100A6 | S100 calcium binding protein A6 | 0.0227828 |
| PRKCA | protein kinase C, alpha | 0.0226492 |
| RCOR1 | REST corepressor 1 | 0.022601 |
| CCDC88A | coiled-coil domain containing 88A | 0.0223584 |
| INSIG1 | insulin induced gene 1 | 0.0222392 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0221624 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | 0.0216353 |
| TMEM165 | transmembrane protein 165 | 0.0214546 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0212053 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.021037 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0210304 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0208177 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0206612 |
| COPA | coatomer protein complex, subunit alpha | 0.0205219 |
| PTK2 | protein tyrosine kinase 2 | 0.0204998 |
| PRR16 | proline rich 16 | 0.0204682 |
| GREB1L | growth regulation by estrogen in breast cancer-like | 0.0204366 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0204273 |
| CUX1 | cut-like homeobox 1 | 0.0203529 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NAMPT | nicotinamide phosphoribosyltransferase | -0.192599 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.164769 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.119691 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0773378 |
| SMAD3 | SMAD family member 3 | -0.0686402 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0608636 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0567282 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.052908 |
| RPLP1 | ribosomal protein, large, P1 | -0.0427754 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0417582 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0402758 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0366815 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.036042 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0359098 |
| RAD51B | RAD51 paralog B | -0.0353453 |
| PRELID2 | PRELI domain containing 2 | -0.0342248 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0320979 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0320711 |
| TXNRD1 | thioredoxin reductase 1 | -0.0313438 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0312693 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0306621 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0302218 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0297655 |
| OGA | O-GlcNAcase | -0.0293822 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0272556 |
| RPL23 | ribosomal protein L23 | -0.0271769 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0268097 |
| ETV6 | ets variant 6 | -0.0267596 |
| KYNU | kynureninase | -0.0252933 |
| RBM39 | RNA binding motif protein 39 | -0.0248166 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0247219 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0242521 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0240921 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0236445 |
| UBE2O | ubiquitin-conjugating enzyme E2O | -0.0233793 |
| RPS19 | ribosomal protein S19 | -0.0233455 |
| RPL34 | ribosomal protein L34 | -0.0231003 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0229629 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.022893 |
| PCBP2 | poly(rC) binding protein 2 | -0.0228864 |
| PTMA | prothymosin, alpha | -0.0227791 |
| RPL36 | ribosomal protein L36 | -0.0224089 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0221735 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0220616 |
| MYOF | myoferlin | -0.0220296 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0217355 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0214398 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0210213 |
| ZNF292 | zinc finger protein 292 | -0.0208532 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0208521 |
| RPS24 | ribosomal protein S24 | -0.0203668 |
| FBXL13 | F-box and leucine-rich repeat protein 13 | -0.0203319 |
| ASPH | aspartate beta-hydroxylase | -0.0202756 |
| RPL12 | ribosomal protein L12 | -0.0202459 |
| YBX1 | Y box binding protein 1 | -0.0202006 |
| IER3 | immediate early response 3 | -0.0201437 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0199982 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0199193 |
| RPL35A | ribosomal protein L35a | -0.0198725 |
| KCTD16 | potassium channel tetramerization domain containing 16 | -0.0195454 |
| METTL15 | methyltransferase like 15 | -0.0194473 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0193884 |
| RPL32 | ribosomal protein L32 | -0.0190963 |
| FBXO32 | F-box protein 32 | -0.0187939 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | -0.018716 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | -0.01853 |
| PRKCE | protein kinase C, epsilon | -0.0183996 |
| EZR | ezrin | -0.0181146 |
| CDH2 | cadherin 2, type 1, N-cadherin (neuronal) | -0.0181096 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0180809 |
| CD44 | CD44 molecule (Indian blood group) | -0.0180292 |
| SYAP1 | synapse associated protein 1 | -0.018022 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0180213 |
| RPS8 | ribosomal protein S8 | -0.0178477 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0178359 |
| RPS20 | ribosomal protein S20 | -0.0178028 |
| RARB | retinoic acid receptor, beta | -0.0177867 |
| RPL13A | ribosomal protein L13a | -0.0177498 |
| RACK1 | receptor for activated C kinase 1 | -0.0175559 |
| SUN1 | Sad1 and UNC84 domain containing 1 | -0.017391 |
| PRKCSH | protein kinase C substrate 80K-H | -0.0170151 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0170085 |
| RPL11 | ribosomal protein L11 | -0.0169858 |
| ACTN4 | actinin, alpha 4 | -0.0166701 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0166285 |
| KIAA1217 | KIAA1217 | -0.0166226 |
| RPS21 | ribosomal protein S21 | -0.0165151 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0164616 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0164593 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0162857 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0161791 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0161464 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0159484 |
| RPL5 | ribosomal protein L5 | -0.0158296 |
| FOXO3 | forkhead box O3 | -0.0158159 |
| XPO1 | exportin 1 | -0.0156767 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0154013 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0153557 |
| RPS29 | ribosomal protein S29 | -0.0153554 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0153483 |
