| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fulvestrant_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.154546 |
| PDE10A | phosphodiesterase 10A | 0.113493 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.111927 |
| FN1 | fibronectin 1 | 0.105811 |
| MYOF | myoferlin | 0.100816 |
| TENM3 | teneurin transmembrane protein 3 | 0.0944569 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0919827 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0820675 |
| PRELID2 | PRELI domain containing 2 | 0.0802639 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0797361 |
| GPC6 | glypican 6 | 0.0741883 |
| GOLGA4 | golgin A4 | 0.0728896 |
| RAD51B | RAD51 paralog B | 0.0711616 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | 0.0643931 |
| CANX | calnexin | 0.0630795 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0607481 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0558271 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0552858 |
| MORF4L2 | mortality factor 4 like 2 | 0.0547874 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0522186 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | 0.0500546 |
| DST | dystonin | 0.0498044 |
| CCNI | cyclin I | 0.0480956 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0477837 |
| TPD52 | tumor protein D52 | 0.0462724 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.044555 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.043942 |
| STC1 | stanniocalcin 1 | 0.0428947 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0419058 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0414385 |
| COPA | coatomer protein complex, subunit alpha | 0.0412091 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0408662 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0399379 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0393588 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0387759 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0387479 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0360202 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0352769 |
| RAB10 | RAB10, member RAS oncogene family | 0.0351294 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0349623 |
| MAP4 | microtubule-associated protein 4 | 0.0343648 |
| WDR43 | WD repeat domain 43 | 0.0335623 |
| EFNA5 | ephrin-A5 | 0.031475 |
| LOXL2 | lysyl oxidase-like 2 | 0.0312136 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0295054 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0293438 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0278695 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0274124 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0273746 |
| UBC | ubiquitin C | 0.0272491 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0265565 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0262343 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0258222 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0239088 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0227511 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0218835 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0218503 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.0215947 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0211494 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0209672 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0207925 |
| S100A9 | S100 calcium binding protein A9 | 0.0204331 |
| RORA | RAR-related orphan receptor A | 0.0201649 |
| SBF2 | SET binding factor 2 | 0.0199553 |
| FLNB | filamin B, beta | 0.0197837 |
| RTN4 | reticulon 4 | 0.0197571 |
| RPS16 | ribosomal protein S16 | 0.0194879 |
| SPAG9 | sperm associated antigen 9 | 0.0194454 |
| JMJD1C | jumonji domain containing 1C | 0.0180215 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0169853 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.0168159 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0162361 |
| RSL24D1 | ribosomal L24 domain containing 1 | 0.0162336 |
| ENO1 | enolase 1, (alpha) | 0.0159169 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0156447 |
| RPL4 | ribosomal protein L4 | 0.0153485 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0150519 |
| RPLP0 | ribosomal protein, large, P0 | 0.0148623 |
| POTEF | POTE ankyrin domain family, member F | 0.0141708 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0141377 |
| TFG | TRK-fused gene | 0.0140097 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0137033 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0132721 |
| RPL23 | ribosomal protein L23 | 0.0131608 |
| USP34 | ubiquitin specific peptidase 34 | 0.0127189 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0124202 |
| RPS12 | ribosomal protein S12 | 0.012403 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0120604 |
| RNF213 | ring finger protein 213 | 0.0103183 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.00982736 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0087584 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.00832343 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.00823938 |
| MAP4K5 | mitogen-activated protein kinase kinase kinase kinase 5 | 0.00777019 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.00672561 |
| SLC38A2 | solute carrier family 38, member 2 | 0.00660224 |
| RPS3 | ribosomal protein S3 | 0.00658054 |
| FBXO11 | F-box protein 11 | 0.00628147 |
| FAM193A | family with sequence similarity 193, member A | 0.00607347 |
| FAM13A | family with sequence similarity 13, member A | 0.00593541 |
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | -0.237235 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.159937 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.135121 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.125316 |
| ATOSA | atos homolog A | -0.114353 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | -0.101101 |
| LAMB3 | laminin, beta 3 | -0.0983334 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0933348 |
| EGFR | epidermal growth factor receptor | -0.0891061 |
| TXNRD1 | thioredoxin reductase 1 | -0.0869549 |
| PTMA | prothymosin, alpha | -0.0848523 |
| SVIL | supervillin | -0.078782 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | -0.0786459 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0733122 |
| ANXA2 | annexin A2 | -0.0728125 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0665949 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.063069 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0589179 |
| PKM | pyruvate kinase, muscle | -0.0563521 |
| AHNAK | AHNAK nucleoprotein | -0.0530221 |
| TMSB10 | thymosin beta 10 | -0.052559 |
| IGF1R | insulin-like growth factor 1 receptor | -0.052459 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0523489 |
| PARD3 | par-3 family cell polarity regulator | -0.0492819 |
| NAV2 | neuron navigator 2 | -0.0459166 |
| B2M | beta-2-microglobulin | -0.0455334 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0444988 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0435787 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0430676 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0424914 |
| EZR | ezrin | -0.0421612 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0417099 |
| KATNBL1 | katanin p80 subunit B-like 1 | -0.04139 |
| RUNX1 | runt-related transcription factor 1 | -0.0413618 |
| ZNF638 | zinc finger protein 638 | -0.0412413 |
| MUC16 | mucin 16, cell surface associated | -0.0409242 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0404812 |
| IGF2 | insulin-like growth factor 2 | -0.0398269 |
| ABHD17C | abhydrolase domain containing 17C | -0.0377143 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0359366 |
| ASPH | aspartate beta-hydroxylase | -0.0354359 |
| RPS6 | ribosomal protein S6 | -0.0343502 |
| SMYD3 | SET and MYND domain containing 3 | -0.0330978 |
| VIM | vimentin | -0.0330143 |
| LAMC2 | laminin, gamma 2 | -0.0324916 |
| TJP1 | tight junction protein 1 | -0.031714 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0313024 |
| ACTG1 | actin gamma 1 | -0.0302507 |
| ERBIN | erbb2 interacting protein | -0.0293969 |
| PAFAH1B1 | platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) | -0.0289876 |
| FTL | ferritin, light polypeptide | -0.0284731 |
| MYO1E | myosin IE | -0.0275407 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0273322 |
| RPL19 | ribosomal protein L19 | -0.027303 |
| SQSTM1 | sequestosome 1 | -0.0261206 |
| MT2A | metallothionein 2A | -0.0256764 |
| PGK1 | phosphoglycerate kinase 1 | -0.02513 |
| RBM47 | RNA binding motif protein 47 | -0.0240722 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0232344 |
| MED13 | mediator complex subunit 13 | -0.0225028 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0214157 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0208544 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.020478 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0201102 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0198589 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0182201 |
| BPTF | bromodomain PHD finger transcription factor | -0.0178014 |
| MED13L | mediator complex subunit 13-like | -0.0175411 |
| MSI2 | musashi RNA-binding protein 2 | -0.0161628 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.016009 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.01572 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0149744 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.01493 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0148465 |
| RPL35A | ribosomal protein L35a | -0.0145392 |
| CLTC | clathrin, heavy chain (Hc) | -0.0145369 |
| RPLP1 | ribosomal protein, large, P1 | -0.0143432 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.01383 |
| NDRG1 | N-myc downstream regulated 1 | -0.0125105 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0120593 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0120203 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0120021 |
| RPL11 | ribosomal protein L11 | -0.011046 |
| LDHA | lactate dehydrogenase A | -0.0105884 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0104208 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0103693 |
| HLA-B | major histocompatibility complex, class I, B | -0.0097618 |
| FMNL2 | formin-like 2 | -0.00972459 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.00944351 |
| ZNF292 | zinc finger protein 292 | -0.00859864 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.008367 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.00805777 |
| GRB10 | growth factor receptor-bound protein 10 | -0.00801699 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0077331 |
| NF1 | neurofibromin 1 | -0.00739228 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.00680495 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.00660048 |
| RPS8 | ribosomal protein S8 | -0.00628495 |
| EXT1 | exostosin glycosyltransferase 1 | -0.00550074 |
| NOP58 | NOP58 ribonucleoprotein | -0.00503869 |
