| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fulvestrant_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.067124 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.052396 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0470724 |
| RPL35A | ribosomal protein L35a | 0.0468746 |
| ANXA1 | annexin A1 | 0.0457707 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0423762 |
| BMP10 | bone morphogenetic protein 10 | 0.0408553 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0394894 |
| PTMA | prothymosin, alpha | 0.0394608 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | 0.0388431 |
| CCND1 | cyclin D1 | 0.0387153 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0362958 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0362119 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0343481 |
| RPL31 | ribosomal protein L31 | 0.0342798 |
| MYOF | myoferlin | 0.0328822 |
| RPL4 | ribosomal protein L4 | 0.0317665 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | 0.0299986 |
| EZR | ezrin | 0.0290851 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.028669 |
| PRELID2 | PRELI domain containing 2 | 0.028613 |
| RPL9 | ribosomal protein L9 | 0.0270158 |
| GPHN | gephyrin | 0.0267728 |
| DSTN | destrin (actin depolymerizing factor) | 0.025994 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0258144 |
| HDAC9 | histone deacetylase 9 | 0.0255953 |
| ARL4C | ADP-ribosylation factor-like 4C | 0.0255898 |
| FER | fer (fps/fes related) tyrosine kinase | 0.0253582 |
| RPS23 | ribosomal protein S23 | 0.0252978 |
| UBA52 | ubiquitin A-52 residue ribosomal protein fusion product 1 | 0.02513 |
| ANK2 | ankyrin 2, neuronal | 0.0250802 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0250609 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0250089 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0241061 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0239061 |
| SQSTM1 | sequestosome 1 | 0.0232072 |
| FHAD1 | forkhead-associated (FHA) phosphopeptide binding domain 1 | 0.0227973 |
| SPRY1 | sprouty homolog 1, antagonist of FGF signaling (Drosophila) | 0.0224114 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.022233 |
| FOXP1 | forkhead box P1 | 0.0221801 |
| UBC | ubiquitin C | 0.02216 |
| RPL8 | ribosomal protein L8 | 0.0220883 |
| ZNF438 | zinc finger protein 438 | 0.0211165 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0207846 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0207133 |
| RPLP2 | ribosomal protein, large, P2 | 0.0205324 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0203041 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0202622 |
| ABLIM1 | actin binding LIM protein 1 | 0.0199966 |
| SPIDR | scaffolding protein involved in DNA repair | 0.0198912 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 0.0198516 |
| STAU2 | staufen double-stranded RNA binding protein 2 | 0.0197846 |
| GCC2 | GRIP and coiled-coil domain containing 2 | 0.0194908 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.019478 |
| RPS13 | ribosomal protein S13 | 0.0193978 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0192688 |
| JMJD1C | jumonji domain containing 1C | 0.0191401 |
| DST | dystonin | 0.0191097 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | 0.0189732 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0187501 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0187322 |
| BTBD9 | BTB (POZ) domain containing 9 | 0.0186752 |
| CUX1 | cut-like homeobox 1 | 0.018625 |
| BPTF | bromodomain PHD finger transcription factor | 0.0185988 |
| ITGA10 | integrin, alpha 10 | 0.0185519 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | 0.0185053 |
| CLOCK | clock circadian regulator | 0.0181732 |
| RPS16 | ribosomal protein S16 | 0.0176987 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0176747 |
| VMP1 | vacuole membrane protein 1 | 0.0176369 |
| ALDH3A2 | aldehyde dehydrogenase 3 family, member A2 | 0.0175423 |
| VPS13C | vacuolar protein sorting 13 homolog C (S. cerevisiae) | 0.0172542 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.01705 |
| TBL1X | transducin (beta)-like 1X-linked | 0.0170385 |
| GOLGB1 | golgin B1 | 0.0170272 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0170242 |
| ASPH | aspartate beta-hydroxylase | 0.0166762 |
| ZNF235 | zinc finger protein 235 | 0.0165478 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0165296 |
| FNIP1 | folliculin interacting protein 1 | 0.0165077 |
| SON | SON DNA binding protein | 0.0163414 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | 0.0163122 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0162655 |
| INO80 | INO80 complex subunit | 0.0162426 |
| GPATCH8 | G patch domain containing 8 | 0.0161336 |
| GAN | gigaxonin | 0.0160932 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0160534 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0160282 |
| ATXN2 | ataxin 2 | 0.015931 |
| RPL7A | ribosomal protein L7a | 0.0158119 |
| NBEA | neurobeachin | 0.0157866 |
| SCAPER | S-phase cyclin A-associated protein in the ER | 0.01566 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | 0.0155769 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0154711 |
| DDX18 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 18 | 0.015386 |
| EXOC4 | exocyst complex component 4 | 0.0152269 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0150694 |
| SP100 | SP100 nuclear antigen | 0.0150147 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0150101 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0150003 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.137481 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.105522 |
| TMSB4X | thymosin beta 4, X-linked | -0.0989756 |
| GOLGA4 | golgin A4 | -0.0834967 |
| QKI | QKI, KH domain containing, RNA binding | -0.0586117 |
| VCL | vinculin | -0.0578191 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0453663 |
| TJP1 | tight junction protein 1 | -0.044377 |
| PGK1 | phosphoglycerate kinase 1 | -0.0438415 |
| PKM | pyruvate kinase, muscle | -0.0404236 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0395995 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0389766 |
| ECT2 | epithelial cell transforming 2 | -0.0378701 |
| GNAS | GNAS complex locus | -0.0378488 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0374244 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0374153 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0361823 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0353938 |
| TXNIP | thioredoxin interacting protein | -0.0347217 |
| NFIA | nuclear factor I/A | -0.0327977 |
| RBM39 | RNA binding motif protein 39 | -0.0307612 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0306384 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0304531 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0299547 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0293048 |
| USP3 | ubiquitin specific peptidase 3 | -0.0292279 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0292142 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.028845 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | -0.0287116 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | -0.0285905 |
| RTN4 | reticulon 4 | -0.0285348 |
| CDC73 | cell division cycle 73 | -0.0285126 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0284714 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0282538 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0281583 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.027605 |
| LDHA | lactate dehydrogenase A | -0.0271755 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0271409 |
| NCKAP1 | NCK-associated protein 1 | -0.0267796 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0265504 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0265195 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | -0.026486 |
| SPRED2 | sprouty-related, EVH1 domain containing 2 | -0.0251281 |
| RHEB | Ras homolog enriched in brain | -0.0250767 |
| HELZ | helicase with zinc finger | -0.024976 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.024954 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | -0.0245208 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | -0.0245043 |
| RPL36 | ribosomal protein L36 | -0.0239754 |
| ZNF292 | zinc finger protein 292 | -0.0238908 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | -0.0238458 |
| CKAP5 | cytoskeleton associated protein 5 | -0.023531 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | -0.0233277 |
| TMEM41B | transmembrane protein 41B | -0.0233011 |
| LOXL3 | lysyl oxidase-like 3 | -0.0232809 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0231436 |
| CALR | calreticulin | -0.0229919 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0227391 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0225623 |
| CENPF | centromere protein F, 350/400kDa | -0.0225302 |
| FBXO11 | F-box protein 11 | -0.0218561 |
| SPAG9 | sperm associated antigen 9 | -0.0215698 |
| NOP58 | NOP58 ribonucleoprotein | -0.0215272 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0212835 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0212237 |
| SMC3 | structural maintenance of chromosomes 3 | -0.0212101 |
| EVI5 | ecotropic viral integration site 5 | -0.0211836 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0211823 |
| RAB6A | RAB6A, member RAS oncogene family | -0.0211138 |
| ATP13A3 | ATPase type 13A3 | -0.0211001 |
| HMGA1 | high mobility group AT-hook 1 | -0.0209246 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.020823 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0207833 |
| PTK2 | protein tyrosine kinase 2 | -0.0204086 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0203894 |
| XPO1 | exportin 1 | -0.0203552 |
| NAP1L4 | nucleosome assembly protein 1-like 4 | -0.0201334 |
| KDM6A | lysine (K)-specific demethylase 6A | -0.0201263 |
| RPS8 | ribosomal protein S8 | -0.0200463 |
| NBAS | neuroblastoma amplified sequence | -0.0199961 |
| ZFC3H1 | zinc finger, C3H1-type containing | -0.0198423 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.019806 |
| MED13L | mediator complex subunit 13-like | -0.0196806 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0196105 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0194211 |
| CANX | calnexin | -0.0193868 |
| RPS6 | ribosomal protein S6 | -0.0192716 |
| SEC24A | SEC24 family member A | -0.019169 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0190963 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | -0.0190157 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.01869 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0185293 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.018477 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | -0.0184015 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.018399 |
| SDCBP | syndecan binding protein (syntenin) | -0.0182111 |
| RBM26 | RNA binding motif protein 26 | -0.0182036 |
| PAQR3 | progestin and adipoQ receptor family member III | -0.0181414 |
| UBA2 | ubiquitin-like modifier activating enzyme 2 | -0.0181117 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0178854 |
