| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fulvestrant_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.127056 |
| PDE10A | phosphodiesterase 10A | 0.0959966 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0954983 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0884654 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0787618 |
| VCL | vinculin | 0.072506 |
| HDAC9 | histone deacetylase 9 | 0.0666559 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0652513 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0640553 |
| FNIP1 | folliculin interacting protein 1 | 0.0567668 |
| TNS3 | tensin 3 | 0.0520758 |
| NAV2 | neuron navigator 2 | 0.0519427 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.049928 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0481943 |
| NDRG1 | N-myc downstream regulated 1 | 0.0481621 |
| RUNX1 | runt-related transcription factor 1 | 0.0475965 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0469987 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0440363 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0436771 |
| LOXL2 | lysyl oxidase-like 2 | 0.0429943 |
| MMP12 | matrix metallopeptidase 12 | 0.0426935 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0423856 |
| FMNL2 | formin-like 2 | 0.0415074 |
| NABP1 | nucleic acid binding protein 1 | 0.0403373 |
| VEGFA | vascular endothelial growth factor A | 0.0401938 |
| MYOF | myoferlin | 0.0400408 |
| PCBP3 | poly(rC) binding protein 3 | 0.0393194 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0393018 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0392657 |
| FLNB | filamin B, beta | 0.037939 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.0376583 |
| ARFGEF3 | ARFGEF family member 3 | 0.0357424 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0356158 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0349391 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0341986 |
| MSN | moesin | 0.034157 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0340765 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0334822 |
| FRMD4A | FERM domain containing 4A | 0.0323149 |
| JMJD1C | jumonji domain containing 1C | 0.0317244 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0300894 |
| FAM219A | family with sequence similarity 219, member A | 0.0299567 |
| ZHX2 | zinc fingers and homeoboxes 2 | 0.0293889 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0291497 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.029024 |
| INTS6 | integrator complex subunit 6 | 0.0289755 |
| VMP1 | vacuole membrane protein 1 | 0.0287511 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0287036 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0285971 |
| NGLY1 | N-glycanase 1 | 0.0285008 |
| UBC | ubiquitin C | 0.0279991 |
| NOTCH2 | notch 2 | 0.0269655 |
| DSCAM | Down syndrome cell adhesion molecule | 0.026963 |
| CEP250 | centrosomal protein 250kDa | 0.0266901 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0260529 |
| RNF24 | ring finger protein 24 | 0.0259183 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0258874 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0256156 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0252015 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0250631 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0248809 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0247014 |
| SDC4 | syndecan 4 | 0.0245264 |
| CDCP1 | CUB domain containing protein 1 | 0.0243641 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0242528 |
| PHF3 | PHD finger protein 3 | 0.0242481 |
| RND3 | Rho family GTPase 3 | 0.0239948 |
| FOXO3 | forkhead box O3 | 0.0237743 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0232595 |
| PLIN2 | perilipin 2 | 0.023102 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0228055 |
| VCAN | versican | 0.0227677 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0225428 |
| FERMT2 | fermitin family member 2 | 0.022277 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0222043 |
| DST | dystonin | 0.0220689 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0219482 |
| CDK19 | cyclin-dependent kinase 19 | 0.0218875 |
| PALLD | palladin, cytoskeletal associated protein | 0.021863 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0218328 |
| GOLGB1 | golgin B1 | 0.0214949 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0214779 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0209281 |
| TGM2 | transglutaminase 2 | 0.0208423 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0207635 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0206438 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0205791 |
| IRAK2 | interleukin-1 receptor-associated kinase 2 | 0.0203682 |
| SEPTIN9 | septin 9 | 0.0199332 |
| CD109 | CD109 molecule | 0.0198347 |
| SETD5 | SET domain containing 5 | 0.0196329 |
| SFRP1 | secreted frizzled-related protein 1 | 0.0196157 |
| EGFR | epidermal growth factor receptor | 0.0195053 |
| OSMR | oncostatin M receptor | 0.0189489 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0188404 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0187131 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0185316 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0185221 |
| SPAG9 | sperm associated antigen 9 | 0.0184415 |
| RAI14 | retinoic acid induced 14 | 0.0181751 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.297983 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.129409 |
| TMSB10 | thymosin beta 10 | -0.12682 |
| HLA-B | major histocompatibility complex, class I, B | -0.123809 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.112668 |
| FN1 | fibronectin 1 | -0.107073 |
| IER3 | immediate early response 3 | -0.101803 |
| RPS6 | ribosomal protein S6 | -0.101247 |
| FTL | ferritin, light polypeptide | -0.0961709 |
| RPS24 | ribosomal protein S24 | -0.0852761 |
| RPL23 | ribosomal protein L23 | -0.0839312 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0836775 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0834746 |
| PTMA | prothymosin, alpha | -0.0828272 |
| RPL35A | ribosomal protein L35a | -0.079217 |
| MT2A | metallothionein 2A | -0.0755722 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0731515 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0669579 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0660475 |
| RPL36A | ribosomal protein L36a | -0.0659313 |
| RPLP0 | ribosomal protein, large, P0 | -0.063031 |
| RPS8 | ribosomal protein S8 | -0.0617561 |
| RPLP1 | ribosomal protein, large, P1 | -0.0614234 |
| RPL12 | ribosomal protein L12 | -0.061226 |
| RPLP2 | ribosomal protein, large, P2 | -0.0599313 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0581666 |
| PGK1 | phosphoglycerate kinase 1 | -0.0570188 |
| RPS23 | ribosomal protein S23 | -0.0568315 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0558014 |
| RPL26 | ribosomal protein L26 | -0.0543695 |
| ACTG1 | actin gamma 1 | -0.0533146 |
| B2M | beta-2-microglobulin | -0.052753 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0525534 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.051652 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0511424 |
| RPS4X | ribosomal protein S4, X-linked | -0.0477759 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0477689 |
| ZNF292 | zinc finger protein 292 | -0.0476569 |
| RPL19 | ribosomal protein L19 | -0.0476126 |
| RPS19 | ribosomal protein S19 | -0.0456469 |
| ANXA2 | annexin A2 | -0.0452882 |
| RPL9 | ribosomal protein L9 | -0.0449111 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0445923 |
| RPL11 | ribosomal protein L11 | -0.0429239 |
| RPL37A | ribosomal protein L37a | -0.0429223 |
| BICC1 | BicC family RNA binding protein 1 | -0.042313 |
| RPS14 | ribosomal protein S14 | -0.0415856 |
| TKT | transketolase | -0.0408796 |
| RPL32 | ribosomal protein L32 | -0.0400457 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0398694 |
| TUBB | tubulin, beta class I | -0.0394696 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0393628 |
| RPS21 | ribosomal protein S21 | -0.0390315 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0389125 |
| RPL7 | ribosomal protein L7 | -0.0384272 |
| TXNRD1 | thioredoxin reductase 1 | -0.0383933 |
| RPS3 | ribosomal protein S3 | -0.0378849 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0376677 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0363884 |
| GNAS | GNAS complex locus | -0.0362603 |
| CALR | calreticulin | -0.0362308 |
| RPS12 | ribosomal protein S12 | -0.036095 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0356437 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0356303 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0355381 |
| POTEF | POTE ankyrin domain family, member F | -0.0352836 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0352324 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0350063 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0341747 |
| DEK | DEK proto-oncogene | -0.0339754 |
| SEPTIN7 | septin 7 | -0.0339085 |
| TMEM123 | transmembrane protein 123 | -0.0336299 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0335314 |
| RPL36 | ribosomal protein L36 | -0.0335221 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0330911 |
| RBM39 | RNA binding motif protein 39 | -0.0329459 |
| TMSB4X | thymosin beta 4, X-linked | -0.0327408 |
| YBX1 | Y box binding protein 1 | -0.0325676 |
| RPL35 | ribosomal protein L35 | -0.032432 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0323072 |
| RPS25 | ribosomal protein S25 | -0.0321425 |
| RPL7A | ribosomal protein L7a | -0.0319586 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0319305 |
| MATR3 | matrin 3 | -0.0312215 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0311363 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0308274 |
| RPL28 | ribosomal protein L28 | -0.0306786 |
| QKI | QKI, KH domain containing, RNA binding | -0.0305601 |
| RPL34 | ribosomal protein L34 | -0.0302418 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0302058 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0296753 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0295999 |
| FAM162A | family with sequence similarity 162, member A | -0.0292473 |
| RPS16 | ribosomal protein S16 | -0.0289123 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0288346 |
| RPL31 | ribosomal protein L31 | -0.028442 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0284254 |
| RPL5 | ribosomal protein L5 | -0.0280373 |
| HMGA1 | high mobility group AT-hook 1 | -0.0280098 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0280014 |
