| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fulvestrant_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.189512 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.127171 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0856186 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0610743 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0596437 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0577428 |
| PTMA | prothymosin, alpha | 0.0555313 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0544889 |
| B2M | beta-2-microglobulin | 0.0509103 |
| FMNL2 | formin-like 2 | 0.0497429 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | 0.0491026 |
| COL5A1 | collagen, type V, alpha 1 | 0.0484384 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0481511 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0469134 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.046648 |
| MORF4L2 | mortality factor 4 like 2 | 0.046598 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0464221 |
| LOXL2 | lysyl oxidase-like 2 | 0.0463402 |
| LAMB3 | laminin, beta 3 | 0.0462785 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0442726 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.0437893 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0433205 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0428117 |
| LAMB1 | laminin, beta 1 | 0.042558 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.042334 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0410661 |
| CDH13 | cadherin 13 | 0.0408579 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0405746 |
| MYOF | myoferlin | 0.0405312 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | 0.0400411 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0399371 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0391882 |
| HLA-A | major histocompatibility complex, class I, A | 0.0386738 |
| NAV1 | neuron navigator 1 | 0.0386583 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0383724 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0382125 |
| HLA-B | major histocompatibility complex, class I, B | 0.0378008 |
| PRKCA | protein kinase C, alpha | 0.0372178 |
| GOLGB1 | golgin B1 | 0.037057 |
| COG5 | component of oligomeric golgi complex 5 | 0.0364006 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0358472 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0352786 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0341344 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0340984 |
| FNIP1 | folliculin interacting protein 1 | 0.0330065 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0327929 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0325008 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0324969 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.0323477 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | 0.0322 |
| CLINT1 | clathrin interactor 1 | 0.0319498 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0314951 |
| ITGAV | integrin, alpha V | 0.0312547 |
| SUCO | SUN domain containing ossification factor | 0.0311597 |
| RSL1D1 | ribosomal L1 domain containing 1 | 0.0304755 |
| AVL9 | AVL9 homolog (S. cerevisiase) | 0.0297407 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.029434 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | 0.029258 |
| NRXN3 | neurexin 3 | 0.0292533 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0291799 |
| NDRG1 | N-myc downstream regulated 1 | 0.0290798 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0290606 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0289537 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0287661 |
| SCAF11 | SR-related CTD-associated factor 11 | 0.0287144 |
| AGO3 | argonaute RISC catalytic component 3 | 0.0286395 |
| IGFBP7 | insulin-like growth factor binding protein 7 | 0.0284963 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0281884 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0281113 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0280355 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0278719 |
| TMEM165 | transmembrane protein 165 | 0.0278465 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0277905 |
| TMEM123 | transmembrane protein 123 | 0.0277643 |
| FSCN1 | fascin actin-bundling protein 1 | 0.0276605 |
| NAV2 | neuron navigator 2 | 0.0274453 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0273527 |
| SBF2 | SET binding factor 2 | 0.0269622 |
| SKIC3 | SKI3 subunit of superkiller complex | 0.0268424 |
| AK1 | adenylate kinase 1 | 0.0267375 |
| FRMD6 | FERM domain containing 6 | 0.0266592 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0266406 |
| FOSL1 | FOS-like antigen 1 | 0.0265879 |
| COG6 | component of oligomeric golgi complex 6 | 0.0265857 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0265244 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0264357 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0262453 |
| STAG2 | stromal antigen 2 | 0.0262368 |
| HLA-E | major histocompatibility complex, class I, E | 0.0256989 |
| NUS1 | nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) | 0.0256518 |
| DPYSL2 | dihydropyrimidinase-like 2 | 0.0256387 |
| SSBP1 | single-stranded DNA binding protein 1, mitochondrial | 0.0255835 |
| ATP13A3 | ATPase type 13A3 | 0.0253837 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0253074 |
| S100A6 | S100 calcium binding protein A6 | 0.0250194 |
| RPS5 | ribosomal protein S5 | 0.0249718 |
| FAM193B | family with sequence similarity 193, member B | 0.0249653 |
| MICAL3 | microtubule associated monooxygenase, calponin and LIM domain containing 3 | 0.0248657 |
| SNX9 | sorting nexin 9 | 0.0247659 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0246062 |
| Symbol | Name | Standardized Value |
|---|---|---|
| MT2A | metallothionein 2A | -0.108299 |
| TMSB10 | thymosin beta 10 | -0.107419 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105995 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0887836 |
| VIM | vimentin | -0.0861442 |
| ENO1 | enolase 1, (alpha) | -0.0800526 |
| LDHA | lactate dehydrogenase A | -0.0777571 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0755191 |
| FN1 | fibronectin 1 | -0.0713327 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0681667 |
| TXNIP | thioredoxin interacting protein | -0.068135 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0678948 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0651468 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0636505 |
| COL1A1 | collagen, type I, alpha 1 | -0.0619231 |
| ANXA5 | annexin A5 | -0.0601675 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0571297 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.0552401 |
| AHNAK | AHNAK nucleoprotein | -0.0542582 |
| FAM13A | family with sequence similarity 13, member A | -0.0541721 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.052307 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0467371 |
| CD44 | CD44 molecule (Indian blood group) | -0.0454696 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0421626 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0414596 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | -0.0412691 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0408919 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | -0.040592 |
| SPAG9 | sperm associated antigen 9 | -0.0403677 |
| JUN | jun proto-oncogene | -0.039752 |
| ATXN1 | ataxin 1 | -0.0397103 |
| MEF2A | myocyte enhancer factor 2A | -0.0391776 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0387813 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0372127 |
| CDK6 | cyclin-dependent kinase 6 | -0.0367959 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0367005 |
| ECE1 | endothelin converting enzyme 1 | -0.0363583 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0360915 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0356309 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0350236 |
| CUL4B | cullin 4B | -0.0347309 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0344224 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0340769 |
| SERINC3 | serine incorporator 3 | -0.0337868 |
| STC2 | stanniocalcin 2 | -0.033388 |
| ARRDC3 | arrestin domain containing 3 | -0.0329612 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | -0.0323734 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0320337 |
| RIGI | RNA sensor RIG-I | -0.0317231 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0314694 |
| EP300 | E1A binding protein p300 | -0.0314682 |
| SOS2 | son of sevenless homolog 2 (Drosophila) | -0.0311522 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0309174 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0307029 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0305531 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0303908 |
| RNF24 | ring finger protein 24 | -0.0303007 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0302071 |
| CAMSAP2 | calmodulin regulated spectrin-associated protein family, member 2 | -0.0300515 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0299743 |
| ADM | adrenomedullin | -0.0298718 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0292807 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | -0.0290041 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0289672 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0287945 |
| IPO7 | importin 7 | -0.028718 |
| FLNB | filamin B, beta | -0.0286929 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0283996 |
| WAPL | WAPL cohesin release factor | -0.0283256 |
| SCRN1 | secernin 1 | -0.0282255 |
| FLNA | filamin A, alpha | -0.0280169 |
| ASPH | aspartate beta-hydroxylase | -0.0279947 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0279301 |
| ARF4 | ADP-ribosylation factor 4 | -0.0279118 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0278146 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.027662 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0276289 |
| CD99 | CD99 molecule | -0.0275377 |
| ZNF207 | zinc finger protein 207 | -0.027534 |
| CABIN1 | calcineurin binding protein 1 | -0.027451 |
| ADNP | activity-dependent neuroprotector homeobox | -0.0272596 |
| SLC20A1 | solute carrier family 20 (phosphate transporter), member 1 | -0.0270658 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | -0.0269372 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.026869 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.0268299 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0268211 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0266834 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0265654 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0263602 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0262889 |
| RAB10 | RAB10, member RAS oncogene family | -0.0261663 |
| RPL37A | ribosomal protein L37a | -0.0261131 |
| RLIM | ring finger protein, LIM domain interacting | -0.0260735 |
| SMAD2 | SMAD family member 2 | -0.026053 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0259856 |
| LOX | lysyl oxidase | -0.0258193 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | -0.0250217 |
| COL1A2 | collagen, type I, alpha 2 | -0.0247279 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0247073 |
| LNPK | lunapark, ER junction formation factor | -0.0246914 |
