| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fulvestrant_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.164172 |
| RPL4 | ribosomal protein L4 | 0.099211 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0939627 |
| EGR1 | early growth response 1 | 0.0905685 |
| SDC4 | syndecan 4 | 0.0874866 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0782524 |
| UBC | ubiquitin C | 0.0691384 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0660631 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0623746 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0608455 |
| DNER | delta/notch-like EGF repeat containing | 0.0549353 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0523949 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0502309 |
| JMJD1C | jumonji domain containing 1C | 0.0489499 |
| TMEM263 | transmembrane protein 263 | 0.0487484 |
| NEDD4 | neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase | 0.0471748 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0464923 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0459411 |
| SEC24A | SEC24 family member A | 0.0447102 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0439441 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0410901 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0404894 |
| PDE8A | phosphodiesterase 8A | 0.0403427 |
| CAPRIN2 | caprin family member 2 | 0.0400204 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | 0.0378226 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | 0.0376388 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0373535 |
| OXSR1 | oxidative stress responsive 1 | 0.0370745 |
| INSIG1 | insulin induced gene 1 | 0.0369863 |
| FLNB | filamin B, beta | 0.0366641 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0356858 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0350398 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0344376 |
| COPA | coatomer protein complex, subunit alpha | 0.0343147 |
| IER3 | immediate early response 3 | 0.0342205 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0340853 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0340631 |
| FMNL2 | formin-like 2 | 0.0337679 |
| ACTG1 | actin gamma 1 | 0.033765 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.033263 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0332014 |
| BSG | basigin (Ok blood group) | 0.0329432 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | 0.0317406 |
| CUL5 | cullin 5 | 0.0310988 |
| BDP1 | B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB | 0.0302484 |
| TCF12 | transcription factor 12 | 0.0297366 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0294365 |
| VIM | vimentin | 0.0284195 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0282101 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0277615 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0275783 |
| CANX | calnexin | 0.0274099 |
| AFDN | afadin, adherens junction formation factor | 0.0270894 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0269338 |
| IFRD1 | interferon-related developmental regulator 1 | 0.0266676 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0263529 |
| RAPGEF6 | Rap guanine nucleotide exchange factor (GEF) 6 | 0.0262196 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0261142 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0260262 |
| SBF2 | SET binding factor 2 | 0.026005 |
| MSANTD3 | Myb/SANT-like DNA-binding domain containing 3 | 0.0259786 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0257613 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0255565 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0251937 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0249868 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0249284 |
| ATP13A3 | ATPase type 13A3 | 0.0248499 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0245882 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0245544 |
| RAB14 | RAB14, member RAS oncogene family | 0.0245262 |
| NPTN | neuroplastin | 0.0245028 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0244549 |
| GPR107 | G protein-coupled receptor 107 | 0.02437 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0243117 |
| APPBP2 | amyloid beta precursor protein (cytoplasmic tail) binding protein 2 | 0.0240797 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0239187 |
| KIAA1958 | KIAA1958 | 0.0238112 |
| ARHGAP21 | Rho GTPase activating protein 21 | 0.0236411 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0233145 |
| TNPO3 | transportin 3 | 0.023257 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0231376 |
| SEPTIN2 | septin 2 | 0.0230786 |
| COG5 | component of oligomeric golgi complex 5 | 0.022934 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0229037 |
| FAM193A | family with sequence similarity 193, member A | 0.0228302 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0227533 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0226159 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0225786 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0225154 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0225041 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0224556 |
| IL1RAP | interleukin 1 receptor accessory protein | 0.0224471 |
| IPO11 | importin 11 | 0.0223483 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0222551 |
| RLIM | ring finger protein, LIM domain interacting | 0.0220715 |
| RORA | RAR-related orphan receptor A | 0.0218602 |
| ANO10 | anoctamin 10 | 0.0218161 |
| OPTN | optineurin | 0.0217459 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0217239 |
| ANXA2 | annexin A2 | 0.0216632 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.117246 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.10114 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0816316 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0734266 |
| CPNE1 | copine I | -0.0596264 |
| ATM | ATM serine/threonine kinase | -0.0569255 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0532865 |
| SMYD3 | SET and MYND domain containing 3 | -0.0496048 |
| GOLGA4 | golgin A4 | -0.0486212 |
| PHF20 | PHD finger protein 20 | -0.0483672 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0481883 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0472264 |
| DST | dystonin | -0.0462186 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0458102 |
| CENPF | centromere protein F, 350/400kDa | -0.0445227 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0436297 |
| RBM39 | RNA binding motif protein 39 | -0.0427983 |
| KIF5B | kinesin family member 5B | -0.0421583 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0416335 |
| HSPA8 | heat shock 70kDa protein 8 | -0.0409646 |
| MRE11 | MRE11 homolog, double strand break repair nuclease | -0.0405203 |
| RPL38 | ribosomal protein L38 | -0.0390251 |
| TPX2 | TPX2, microtubule-associated | -0.0386534 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0381597 |
| CENPP | centromere protein P | -0.0379815 |
| ANLN | anillin, actin binding protein | -0.037111 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0370996 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0367885 |
| YAP1 | Yes-associated protein 1 | -0.0364357 |
| RPL26 | ribosomal protein L26 | -0.0361907 |
| RPLP1 | ribosomal protein, large, P1 | -0.0361526 |
| CEP170 | centrosomal protein 170kDa | -0.0352552 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | -0.0350129 |
| CKAP5 | cytoskeleton associated protein 5 | -0.0345949 |
| TJP2 | tight junction protein 2 | -0.0342005 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0340719 |
| LMNA | lamin A/C | -0.0337305 |
| SCAF8 | SR-related CTD-associated factor 8 | -0.033489 |
| MT2A | metallothionein 2A | -0.0334616 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0334583 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0331917 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0331449 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0328118 |
| RPS3 | ribosomal protein S3 | -0.0327862 |
| HMGA2 | high mobility group AT-hook 2 | -0.0327007 |
| TMEM123 | transmembrane protein 123 | -0.0314787 |
| NUP58 | nucleoporin 58 | -0.0314699 |
| UBQLN1 | ubiquilin 1 | -0.0312795 |
| METTL15 | methyltransferase like 15 | -0.031237 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0312174 |
| SCAPER | S-phase cyclin A-associated protein in the ER | -0.0309615 |
| KIF4A | kinesin family member 4A | -0.0308323 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0303433 |
| AK1 | adenylate kinase 1 | -0.0302026 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0296238 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0295016 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0293675 |
| TXNRD1 | thioredoxin reductase 1 | -0.0289492 |
| ATP9B | ATPase, class II, type 9B | -0.0287202 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0286341 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0285209 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.028342 |
| TM9SF2 | transmembrane 9 superfamily member 2 | -0.0282824 |
| MYO10 | myosin X | -0.0280907 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0280589 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.027908 |
| RPL36 | ribosomal protein L36 | -0.0277452 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0277117 |
| ETV1 | ets variant 1 | -0.0276487 |
| NCKAP1 | NCK-associated protein 1 | -0.0275293 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0272376 |
| SNX14 | sorting nexin 14 | -0.0272058 |
| PHIP | pleckstrin homology domain interacting protein | -0.0270944 |
| RPLP2 | ribosomal protein, large, P2 | -0.0269539 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0269345 |
| OSBPL6 | oxysterol binding protein-like 6 | -0.0268938 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0268416 |
| SEPTIN9 | septin 9 | -0.0267013 |
| SSH2 | slingshot protein phosphatase 2 | -0.0266326 |
| CTTN | cortactin | -0.0265449 |
| RPS17 | ribosomal protein S17 | -0.0264865 |
| SMAD3 | SMAD family member 3 | -0.0262946 |
| RPS20 | ribosomal protein S20 | -0.0262073 |
| NT5E | 5'-nucleotidase, ecto (CD73) | -0.0261631 |
| CNKSR3 | CNKSR family member 3 | -0.0261288 |
| SETX | senataxin | -0.0260005 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0258775 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0256355 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0255025 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0251678 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0251585 |
| KIF2A | kinesin heavy chain member 2A | -0.0250275 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.0250241 |
| RAD51B | RAD51 paralog B | -0.024912 |
| RPS12 | ribosomal protein S12 | -0.0248998 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | -0.0248792 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0248597 |
| EFL1 | elongation factor like GTPase 1 | -0.0248037 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | -0.0245106 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | -0.0244517 |
