| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fulvestrant perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fulvestrant_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.0785864 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0625384 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0605911 |
| UBC | ubiquitin C | 0.0555134 |
| GOLGA4 | golgin A4 | 0.053204 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0526976 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0494715 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0471139 |
| LOXL2 | lysyl oxidase-like 2 | 0.0465588 |
| COPA | coatomer protein complex, subunit alpha | 0.0462334 |
| OSMR | oncostatin M receptor | 0.0441733 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0437449 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0433555 |
| RASAL2 | RAS protein activator like 2 | 0.0433097 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0430745 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0429795 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0423937 |
| SDC4 | syndecan 4 | 0.041283 |
| DENND5B | DENN/MADD domain containing 5B | 0.0401621 |
| SFTPA2 | surfactant protein A2 | 0.0400637 |
| WDR26 | WD repeat domain 26 | 0.0396449 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0386587 |
| FAM3C | family with sequence similarity 3, member C | 0.0377539 |
| SUCO | SUN domain containing ossification factor | 0.0374167 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0365325 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0364327 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0364137 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0363484 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.035676 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | 0.0353763 |
| MAPKAPK2 | mitogen-activated protein kinase-activated protein kinase 2 | 0.0341159 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0335651 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0335622 |
| OGA | O-GlcNAcase | 0.0325333 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0322729 |
| TXNIP | thioredoxin interacting protein | 0.0317585 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0313353 |
| VEGFA | vascular endothelial growth factor A | 0.0306944 |
| ETNK1 | ethanolamine kinase 1 | 0.030671 |
| BRD2 | bromodomain containing 2 | 0.0306482 |
| GOLT1B | golgi transport 1B | 0.0304019 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0301042 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0300958 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0296947 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0295833 |
| RAI14 | retinoic acid induced 14 | 0.0292653 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0290389 |
| TMEM165 | transmembrane protein 165 | 0.0290203 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0284173 |
| LCOR | ligand dependent nuclear receptor corepressor | 0.0283667 |
| ADIPOR2 | adiponectin receptor 2 | 0.0282308 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.028109 |
| USP53 | ubiquitin specific peptidase 53 | 0.0279247 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0278284 |
| MAPK8 | mitogen-activated protein kinase 8 | 0.0277112 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0274959 |
| IL6ST | interleukin 6 signal transducer | 0.0274655 |
| THOC2 | THO complex 2 | 0.0273192 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0271303 |
| JMJD1C | jumonji domain containing 1C | 0.0270221 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0268316 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0267515 |
| COG5 | component of oligomeric golgi complex 5 | 0.0266717 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0260476 |
| PRPF3 | pre-mRNA processing factor 3 | 0.025987 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0257012 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0256789 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0255225 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | 0.0254109 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0253585 |
| TNS3 | tensin 3 | 0.0252799 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.025255 |
| RAB31 | RAB31, member RAS oncogene family | 0.0252398 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0252259 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | 0.0250658 |
| TGM2 | transglutaminase 2 | 0.0248602 |
| GPC6 | glypican 6 | 0.0247482 |
| WDR43 | WD repeat domain 43 | 0.0243904 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0243834 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0243651 |
| AEBP2 | AE binding protein 2 | 0.0243136 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0241885 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0240764 |
| ZBTB35 | zinc finger and BTB domain containing 35 | 0.0240226 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0239292 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0238889 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0238844 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | 0.0237552 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.0233735 |
| DUSP6 | dual specificity phosphatase 6 | 0.0233659 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0232841 |
| CCNYL1 | cyclin Y-like 1 | 0.0231698 |
| CUL3 | cullin 3 | 0.0230379 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0228505 |
| DAAM1 | dishevelled associated activator of morphogenesis 1 | 0.0224985 |
| SENP5 | SUMO1/sentrin specific peptidase 5 | 0.0222463 |
| TGFB2 | transforming growth factor, beta 2 | 0.0220529 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.021909 |
| RIC1 | RAB6A GEF complex partner 1 | 0.0218533 |
| NLK | nemo-like kinase | 0.0215869 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.263402 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.21004 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.168356 |
| ASPH | aspartate beta-hydroxylase | -0.142715 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.134486 |
| NRG1 | neuregulin 1 | -0.123437 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.120869 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.120824 |
| FN1 | fibronectin 1 | -0.10092 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0965364 |
| PTMA | prothymosin, alpha | -0.0946698 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0833045 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0706984 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0697098 |
| RPL35A | ribosomal protein L35a | -0.069482 |
| ZNF292 | zinc finger protein 292 | -0.0659434 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0647403 |
| RPL12 | ribosomal protein L12 | -0.0621727 |
| CANX | calnexin | -0.0612465 |
| SQSTM1 | sequestosome 1 | -0.0610708 |
| PTK2 | protein tyrosine kinase 2 | -0.0603007 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0567988 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0543532 |
| RPS6 | ribosomal protein S6 | -0.0531273 |
| CENPF | centromere protein F, 350/400kDa | -0.0526477 |
| TMSB10 | thymosin beta 10 | -0.0496429 |
| RPS8 | ribosomal protein S8 | -0.0483436 |
| RPL34 | ribosomal protein L34 | -0.046334 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0462488 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0444556 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0430613 |
| IER3 | immediate early response 3 | -0.0430433 |
| HMGA2 | high mobility group AT-hook 2 | -0.0426332 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0420452 |
| FTL | ferritin, light polypeptide | -0.0418251 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0411723 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0402554 |
| KPNB1 | karyopherin (importin) beta 1 | -0.039796 |
| FOXP1 | forkhead box P1 | -0.0380296 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0380104 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0372882 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0371991 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0371452 |
| RPL23 | ribosomal protein L23 | -0.0370721 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0368549 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0365274 |
| HMGA1 | high mobility group AT-hook 1 | -0.0358411 |
| TXNRD1 | thioredoxin reductase 1 | -0.0358153 |
| MKI67 | marker of proliferation Ki-67 | -0.0355047 |
| HLA-B | major histocompatibility complex, class I, B | -0.0352176 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0347763 |
| CXCL1 | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | -0.0347738 |
| RPLP1 | ribosomal protein, large, P1 | -0.0347412 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0346949 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0344434 |
| TMSB4X | thymosin beta 4, X-linked | -0.0340879 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0337335 |
| LDHA | lactate dehydrogenase A | -0.0336116 |
| MORF4L2 | mortality factor 4 like 2 | -0.0335318 |
| FAM13A | family with sequence similarity 13, member A | -0.0332785 |
| SKAP2 | src kinase associated phosphoprotein 2 | -0.0330591 |
| TPI1 | triosephosphate isomerase 1 | -0.0326391 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0316878 |
| RPL31 | ribosomal protein L31 | -0.0310647 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0310273 |
| ITGA1 | integrin, alpha 1 | -0.0306907 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0304666 |
| VIM | vimentin | -0.0302488 |
| SGO2 | shugoshin 2 | -0.0302228 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0301772 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0301626 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0296597 |
| POTEF | POTE ankyrin domain family, member F | -0.029581 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0295259 |
| AHNAK | AHNAK nucleoprotein | -0.0294514 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0294123 |
| B2M | beta-2-microglobulin | -0.0292872 |
| OLA1 | Obg-like ATPase 1 | -0.029015 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | -0.0289506 |
| STC1 | stanniocalcin 1 | -0.0284172 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0283846 |
| RPL26 | ribosomal protein L26 | -0.0283563 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0280556 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0279713 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0279246 |
| RAD51B | RAD51 paralog B | -0.027912 |
| ETV1 | ets variant 1 | -0.0276585 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0274954 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | -0.0274086 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0268908 |
| ANXA5 | annexin A5 | -0.0267701 |
| ATF3 | activating transcription factor 3 | -0.0265286 |
| MEF2A | myocyte enhancer factor 2A | -0.0263637 |
| KCMF1 | potassium channel modulatory factor 1 | -0.0263148 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0261385 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0252669 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0252407 |
| HMGB1 | high mobility group box 1 | -0.0251513 |
| CD109 | CD109 molecule | -0.0250503 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0250028 |
