| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.142652 |
| PODXL | podocalyxin-like | 0.117435 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.110789 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.109216 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0947725 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0892617 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0877807 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0870676 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.076016 |
| COL1A2 | collagen, type I, alpha 2 | 0.0678495 |
| FBN1 | fibrillin 1 | 0.0642157 |
| FLNB | filamin B, beta | 0.0641233 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0634859 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0581129 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0553409 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0530886 |
| SEPTIN9 | septin 9 | 0.0493268 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0479264 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0458001 |
| APP | amyloid beta (A4) precursor protein | 0.0441548 |
| C1D | C1D nuclear receptor corepressor | 0.0436053 |
| PLAT | plasminogen activator, tissue | 0.042721 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0408366 |
| B2M | beta-2-microglobulin | 0.0405682 |
| NAV1 | neuron navigator 1 | 0.0405592 |
| ATP13A3 | ATPase type 13A3 | 0.0399386 |
| MSN | moesin | 0.0394768 |
| MT2A | metallothionein 2A | 0.0389794 |
| HLA-B | major histocompatibility complex, class I, B | 0.0389396 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0385239 |
| PLEC | plectin | 0.0385216 |
| OPTN | optineurin | 0.0376627 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.037513 |
| LOXL2 | lysyl oxidase-like 2 | 0.0374711 |
| DBN1 | drebrin 1 | 0.036656 |
| VEGFA | vascular endothelial growth factor A | 0.0365721 |
| FLNA | filamin A, alpha | 0.0361782 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0360366 |
| AFDN | afadin, adherens junction formation factor | 0.0351401 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0347663 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0347662 |
| DPYSL3 | dihydropyrimidinase-like 3 | 0.0347002 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0338877 |
| NONO | non-POU domain containing, octamer-binding | 0.0338578 |
| GPC6 | glypican 6 | 0.0335287 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0333054 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0329192 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0322446 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0312625 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0295092 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0294838 |
| TMSB4X | thymosin beta 4, X-linked | 0.0293532 |
| STC1 | stanniocalcin 1 | 0.0292643 |
| MINK1 | misshapen-like kinase 1 | 0.0286339 |
| SFTPA2 | surfactant protein A2 | 0.0286208 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0285735 |
| NAV2 | neuron navigator 2 | 0.0280151 |
| PLXNA3 | plexin A3 | 0.0266441 |
| TPM3 | tropomyosin 3 | 0.0265895 |
| HLA-A | major histocompatibility complex, class I, A | 0.0261737 |
| RPL3 | ribosomal protein L3 | 0.0261015 |
| YEATS2 | YEATS domain containing 2 | 0.0260108 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0257497 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0257145 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0254042 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0250229 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0248227 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0243227 |
| IQSEC1 | IQ motif and Sec7 domain 1 | 0.0242524 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0241618 |
| HRNR | hornerin | 0.0241035 |
| SP3 | Sp3 transcription factor | 0.0241031 |
| TMOD1 | tropomodulin 1 | 0.02406 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0237586 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0235634 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0235571 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0232896 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0230552 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.022946 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0229067 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0226934 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0225444 |
| PFKP | phosphofructokinase, platelet | 0.0222479 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0218868 |
| GOLGA2 | golgin A2 | 0.0217905 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0217545 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0213169 |
| SETD5 | SET domain containing 5 | 0.0210719 |
| FOSL1 | FOS-like antigen 1 | 0.0207985 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0199535 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0198669 |
| TTC7A | tetratricopeptide repeat domain 7A | 0.0198291 |
| CEP250 | centrosomal protein 250kDa | 0.0198169 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0197852 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0193949 |
| MTSS1 | metastasis suppressor 1 | 0.0193399 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0192793 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0192726 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0191553 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.019127 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.343529 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.319726 |
| AHNAK | AHNAK nucleoprotein | -0.119393 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.106969 |
| VIM | vimentin | -0.105797 |
| S100A10 | S100 calcium binding protein A10 | -0.104773 |
| CDH13 | cadherin 13 | -0.0949394 |
| LOX | lysyl oxidase | -0.0944297 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0938901 |
| CANX | calnexin | -0.0915516 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0851667 |
| FN1 | fibronectin 1 | -0.0847244 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0822859 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0810125 |
| RIGI | RNA sensor RIG-I | -0.0798976 |
| MAP1B | microtubule-associated protein 1B | -0.0791612 |
| CSTB | cystatin B (stefin B) | -0.0712154 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0680501 |
| CCND1 | cyclin D1 | -0.0667083 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0603753 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0588681 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0538105 |
| SP100 | SP100 nuclear antigen | -0.0515589 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0501577 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0489944 |
| FSTL1 | follistatin-like 1 | -0.0457387 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0426918 |
| ASPH | aspartate beta-hydroxylase | -0.042611 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0402591 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0397726 |
| THBS2 | thrombospondin 2 | -0.039352 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0391863 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0388405 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0381995 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0379064 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0377475 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0373681 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0371601 |
| PRSS23 | protease, serine, 23 | -0.0369988 |
| UBC | ubiquitin C | -0.0365148 |
| IL7R | interleukin 7 receptor | -0.0354505 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0351735 |
| DCLK2 | doublecortin-like kinase 2 | -0.0351631 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0350205 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0347801 |
| ANXA2 | annexin A2 | -0.034441 |
| COL3A1 | collagen, type III, alpha 1 | -0.0344189 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0343292 |
| LMNA | lamin A/C | -0.034211 |
| SEPTIN7 | septin 7 | -0.0338067 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0335669 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0324211 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0323003 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.031832 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0317321 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0316479 |
| LRRC17 | leucine rich repeat containing 17 | -0.031151 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0307681 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0304423 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0302774 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0300891 |
| RASAL2 | RAS protein activator like 2 | -0.0296786 |
| EFNA5 | ephrin-A5 | -0.0296753 |
| CD99 | CD99 molecule | -0.0291105 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0289745 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0288527 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0287316 |
| FLT1 | fms-related tyrosine kinase 1 | -0.0286441 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0278366 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0276765 |
| RPS6KA2 | ribosomal protein S6 kinase, 90kDa, polypeptide 2 | -0.0275483 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0273393 |
| EGFR | epidermal growth factor receptor | -0.0271374 |
| CDK13 | cyclin-dependent kinase 13 | -0.0268783 |
| CYTH3 | cytohesin 3 | -0.0266943 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.026678 |
| TAOK1 | TAO kinase 1 | -0.0265298 |
| PCDH7 | protocadherin 7 | -0.0260396 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0257096 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0256385 |
| CUX1 | cut-like homeobox 1 | -0.0254468 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0254112 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.02521 |
| SQSTM1 | sequestosome 1 | -0.0251982 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0249987 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0247795 |
| RPS15 | ribosomal protein S15 | -0.0246374 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.024526 |
| MAP4 | microtubule-associated protein 4 | -0.0245253 |
| HSPB1 | heat shock 27kDa protein 1 | -0.024477 |
| NDRG1 | N-myc downstream regulated 1 | -0.0241708 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0239961 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0239271 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.023797 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0236704 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0235671 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.023082 |
| FMN2 | formin 2 | -0.023013 |
| RRBP1 | ribosome binding protein 1 | -0.0228177 |
| JMJD1C | jumonji domain containing 1C | -0.0226183 |
