| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.143875 |
| PTMA | prothymosin, alpha | 0.100714 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0803661 |
| NLGN1 | neuroligin 1 | 0.0584816 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0565182 |
| CMIP | c-Maf inducing protein | 0.0552519 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.050544 |
| CALR | calreticulin | 0.0504293 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0493906 |
| RPL23 | ribosomal protein L23 | 0.0485586 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0440486 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0435865 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0421473 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0418543 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0409781 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | 0.0408492 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0402254 |
| FUS | FUS RNA binding protein | 0.0379727 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0368257 |
| KRR1 | KRR1, small subunit (SSU) processome component, homolog (yeast) | 0.0366207 |
| HLA-A | major histocompatibility complex, class I, A | 0.0350422 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0349835 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0344363 |
| TGM2 | transglutaminase 2 | 0.0340667 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0335682 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0335129 |
| FLNA | filamin A, alpha | 0.0332879 |
| PLEC | plectin | 0.0332803 |
| PGK1 | phosphoglycerate kinase 1 | 0.033176 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0322059 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0320484 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0316208 |
| OLR1 | oxidized low density lipoprotein (lectin-like) receptor 1 | 0.0315606 |
| DRAP1 | DR1-associated protein 1 (negative cofactor 2 alpha) | 0.0301842 |
| CELF2 | CUGBP, Elav-like family member 2 | 0.0297178 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0297037 |
| DST | dystonin | 0.029628 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0291223 |
| RPS3 | ribosomal protein S3 | 0.0290261 |
| HMGA2 | high mobility group AT-hook 2 | 0.0289332 |
| NHSL1 | NHS-like 1 | 0.0287965 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0282011 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.027935 |
| RPL13A | ribosomal protein L13a | 0.0276021 |
| WDR43 | WD repeat domain 43 | 0.0275771 |
| ASPH | aspartate beta-hydroxylase | 0.027541 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0272466 |
| SRSF1 | serine/arginine-rich splicing factor 1 | 0.0271848 |
| GASK1B | golgi associated kinase 1B | 0.0271775 |
| LOC112694756 | uncharaterized LOC112694756 | 0.027047 |
| APP | amyloid beta (A4) precursor protein | 0.0268201 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0267018 |
| ACTN4 | actinin, alpha 4 | 0.0263987 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0263031 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0257309 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0256489 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0253915 |
| TSPAN9 | tetraspanin 9 | 0.025391 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0248634 |
| PDCD6 | programmed cell death 6 | 0.0247261 |
| LDHA | lactate dehydrogenase A | 0.0246156 |
| TENM3 | teneurin transmembrane protein 3 | 0.0241823 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0240923 |
| DNMT1 | DNA (cytosine-5-)-methyltransferase 1 | 0.0240173 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0239912 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0237989 |
| PGGHG | protein-glucosylgalactosylhydroxylysine glucosidase | 0.0236639 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0236523 |
| GANAB | glucosidase, alpha; neutral AB | 0.0236391 |
| RPL3 | ribosomal protein L3 | 0.0235236 |
| AXIN2 | axin 2 | 0.0229745 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0229277 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0229176 |
| DENND5A | DENN/MADD domain containing 5A | 0.0224023 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.022401 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0223695 |
| KRT8 | keratin 8, type II | 0.0223674 |
| MSI2 | musashi RNA-binding protein 2 | 0.022348 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0222593 |
| TCOF1 | Treacher Collins-Franceschetti syndrome 1 | 0.0221875 |
| ANXA2 | annexin A2 | 0.0221307 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0217818 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0217723 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | 0.0216483 |
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | 0.0216267 |
| RPL37 | ribosomal protein L37 | 0.0215055 |
| ACTG1 | actin gamma 1 | 0.0213381 |
| NONO | non-POU domain containing, octamer-binding | 0.0211831 |
| NSD2 | nuclear receptor binding SET domain protein 2 | 0.0210997 |
| HDAC4 | histone deacetylase 4 | 0.0210811 |
| EGR1 | early growth response 1 | 0.0209623 |
| ECT2 | epithelial cell transforming 2 | 0.020941 |
| PKM | pyruvate kinase, muscle | 0.0209051 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0206752 |
| INTS6 | integrator complex subunit 6 | 0.0206697 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0206333 |
| PER1 | period circadian clock 1 | 0.0203672 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0201941 |
| RPL35A | ribosomal protein L35a | 0.0200357 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0199878 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.252303 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.139999 |
| MMP12 | matrix metallopeptidase 12 | -0.123509 |
| RPS2 | ribosomal protein S2 | -0.106019 |
| AREG | amphiregulin | -0.102692 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0817472 |
| JMJD1C | jumonji domain containing 1C | -0.0769188 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0731928 |
| TXNRD1 | thioredoxin reductase 1 | -0.0705246 |
| SLC38A2 | solute carrier family 38, member 2 | -0.067883 |
| VMP1 | vacuole membrane protein 1 | -0.064442 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0605383 |
| CLTC | clathrin, heavy chain (Hc) | -0.0601494 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0583399 |
| FTL | ferritin, light polypeptide | -0.0575989 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0516092 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0515797 |
| USP34 | ubiquitin specific peptidase 34 | -0.0502222 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0489051 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0457456 |
| PRKCI | protein kinase C, iota | -0.0449433 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0442467 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0431066 |
| ZNF804A | zinc finger protein 804A | -0.0422451 |
| RTN4 | reticulon 4 | -0.0419625 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0416235 |
| IL6ST | interleukin 6 signal transducer | -0.0414969 |
| TMEM41B | transmembrane protein 41B | -0.0402805 |
| EXOC6B | exocyst complex component 6B | -0.040237 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0397499 |
| FBXO11 | F-box protein 11 | -0.0393752 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0385717 |
| PREPL | prolyl endopeptidase-like | -0.0380403 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0371929 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0370805 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0360952 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0359442 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0356052 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0347494 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0346475 |
| MAP1B | microtubule-associated protein 1B | -0.0345428 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0344945 |
| GOLGB1 | golgin B1 | -0.0344294 |
| RAB10 | RAB10, member RAS oncogene family | -0.0333109 |
| RAB1A | RAB1A, member RAS oncogene family | -0.032184 |
| ZNF292 | zinc finger protein 292 | -0.0319883 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0319562 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.0319166 |
| NKTR | natural killer cell triggering receptor | -0.0316268 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0314246 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0314218 |
| KIF5B | kinesin family member 5B | -0.0312776 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0307428 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0307398 |
| IPO7 | importin 7 | -0.0306936 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.030565 |
| RPS6 | ribosomal protein S6 | -0.0304641 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0303391 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0302927 |
| SEC22A | SEC22 vesicle trafficking protein homolog A (S. cerevisiae) | -0.0284452 |
| RO60 | Ro60, Y RNA binding protein | -0.0283773 |
| CPOX | coproporphyrinogen oxidase | -0.0281336 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0278558 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0276424 |
| RPL12 | ribosomal protein L12 | -0.0273798 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.027323 |
| EPHA6 | EPH receptor A6 | -0.0272825 |
| KLHL24 | kelch-like family member 24 | -0.0272788 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0270136 |
| PCM1 | pericentriolar material 1 | -0.0270103 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0269118 |
| GNB4 | guanine nucleotide binding protein (G protein), beta polypeptide 4 | -0.0268 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0265903 |
| EDN1 | endothelin 1 | -0.026532 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0263667 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0260637 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0259956 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0259394 |
| WASF2 | WAS protein family, member 2 | -0.0255297 |
| XPO1 | exportin 1 | -0.0255236 |
| GOLGA4 | golgin A4 | -0.0254663 |
| CXADR | coxsackie virus and adenovirus receptor | -0.025394 |
| H1-0 | H1.0 linker histone | -0.02509 |
| CCDC88A | coiled-coil domain containing 88A | -0.0250525 |
| SETD5 | SET domain containing 5 | -0.0247638 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | -0.0245958 |
| MGAT4C | MGAT4 family, member C | -0.0245919 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0245876 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0243659 |
| UBXN4 | UBX domain protein 4 | -0.0241692 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0240257 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0238646 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0238306 |
| PAPOLA | poly(A) polymerase alpha | -0.0232745 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0232371 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.023125 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.0230844 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0229715 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0229045 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0228823 |
