| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in A498 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_A498 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ASPH | aspartate beta-hydroxylase | 0.187423 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.178899 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.103072 |
| CCL2 | chemokine (C-C motif) ligand 2 | 0.0874784 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0803904 |
| APOL1 | apolipoprotein L, 1 | 0.079089 |
| APP | amyloid beta (A4) precursor protein | 0.0785425 |
| TXNRD1 | thioredoxin reductase 1 | 0.0677183 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.064335 |
| HLA-B | major histocompatibility complex, class I, B | 0.0632181 |
| SMAD3 | SMAD family member 3 | 0.0621675 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0610688 |
| NRP2 | neuropilin 2 | 0.0599167 |
| DENND2B | DENN domain containing 2B | 0.0594931 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0567631 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0556091 |
| CP | ceruloplasmin (ferroxidase) | 0.0544755 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0515783 |
| RRBP1 | ribosome binding protein 1 | 0.0473545 |
| RPL3 | ribosomal protein L3 | 0.0445191 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0441762 |
| G0S2 | G0/G1 switch 2 | 0.0433402 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0432771 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0426282 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0416311 |
| NONO | non-POU domain containing, octamer-binding | 0.04145 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0408344 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0408342 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0408128 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.040585 |
| RBM39 | RNA binding motif protein 39 | 0.0402346 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0397611 |
| RPL4 | ribosomal protein L4 | 0.0391441 |
| CALU | calumenin | 0.0389708 |
| CA12 | carbonic anhydrase XII | 0.0388636 |
| B2M | beta-2-microglobulin | 0.0383196 |
| PTMA | prothymosin, alpha | 0.038276 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0381217 |
| MSN | moesin | 0.0379643 |
| SET | SET nuclear proto-oncogene | 0.0365957 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0364721 |
| TPM3 | tropomyosin 3 | 0.0364468 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | 0.0361581 |
| CALR | calreticulin | 0.035789 |
| HLA-A | major histocompatibility complex, class I, A | 0.0343484 |
| ANLN | anillin, actin binding protein | 0.0339914 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0334341 |
| PLEC | plectin | 0.0321963 |
| CENPF | centromere protein F, 350/400kDa | 0.0318209 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0317548 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0311862 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0310542 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.031037 |
| P3H2 | prolyl 3-hydroxylase 2 | 0.0309749 |
| FLNA | filamin A, alpha | 0.0309659 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0309287 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0304899 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0304839 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0302571 |
| NFIB | nuclear factor I/B | 0.0302354 |
| ACTN4 | actinin, alpha 4 | 0.0302326 |
| PBX1 | pre-B-cell leukemia homeobox 1 | 0.0302072 |
| IRS2 | insulin receptor substrate 2 | 0.0301412 |
| RNF213 | ring finger protein 213 | 0.03011 |
| ICAM1 | intercellular adhesion molecule 1 | 0.0300006 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0299674 |
| RRM2 | ribonucleotide reductase M2 | 0.0299204 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0293402 |
| PTGR1 | prostaglandin reductase 1 | 0.029225 |
| ANKRD33B | ankyrin repeat domain 33B | 0.0290382 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.028708 |
| MT2A | metallothionein 2A | 0.0283245 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0281731 |
| FAT1 | FAT atypical cadherin 1 | 0.0281695 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0280148 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0277782 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0276585 |
| APOL2 | apolipoprotein L, 2 | 0.0273813 |
| LMNA | lamin A/C | 0.0273659 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0272636 |
| DAPK1 | death-associated protein kinase 1 | 0.027239 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0271175 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0271094 |
| TRIM56 | tripartite motif containing 56 | 0.0269743 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0269224 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.026811 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.026526 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.026233 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0260251 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0260028 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0259165 |
| GPR107 | G protein-coupled receptor 107 | 0.0256725 |
| HPCAL1 | hippocalcin-like 1 | 0.0254602 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0253952 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0250717 |
| JUN | jun proto-oncogene | 0.0250712 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0249061 |
| SDC4 | syndecan 4 | 0.0245087 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.0244872 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0244616 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.182978 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.168892 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0971358 |
| VIM | vimentin | -0.091586 |
| EXT1 | exostosin glycosyltransferase 1 | -0.085871 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0797642 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0780325 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0779116 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0683557 |
| INTS6 | integrator complex subunit 6 | -0.0615238 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0563971 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0563141 |
| FTL | ferritin, light polypeptide | -0.0542341 |
| GPC6 | glypican 6 | -0.0541779 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0507894 |
| GOLGB1 | golgin B1 | -0.0496835 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0489508 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0488779 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0479488 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0469885 |
| KYNU | kynureninase | -0.046518 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0458986 |
| VCL | vinculin | -0.0458291 |
| COG5 | component of oligomeric golgi complex 5 | -0.0447991 |
| PALLD | palladin, cytoskeletal associated protein | -0.0446166 |
| RAI14 | retinoic acid induced 14 | -0.0440973 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0429997 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0425762 |
| NUP98 | nucleoporin 98kDa | -0.0420428 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0405666 |
| EGFR | epidermal growth factor receptor | -0.0404321 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0399519 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0392117 |
| COG6 | component of oligomeric golgi complex 6 | -0.038546 |
| UBC | ubiquitin C | -0.0383485 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0377926 |
| FRMD4A | FERM domain containing 4A | -0.0368788 |
| PLIN2 | perilipin 2 | -0.0362932 |
| GDI2 | GDP dissociation inhibitor 2 | -0.0362366 |
| CREB5 | cAMP responsive element binding protein 5 | -0.0358865 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0356314 |
| SP100 | SP100 nuclear antigen | -0.0351941 |
| RAB1A | RAB1A, member RAS oncogene family | -0.034146 |
| CANX | calnexin | -0.0334394 |
| CTSD | cathepsin D | -0.0332526 |
| NDRG1 | N-myc downstream regulated 1 | -0.0331568 |
| SETX | senataxin | -0.032675 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.03241 |
| AHNAK | AHNAK nucleoprotein | -0.0321443 |
| UBAP2 | ubiquitin associated protein 2 | -0.0321138 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0316378 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0314921 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0312613 |
| SLC31A1 | solute carrier family 31 (copper transporter), member 1 | -0.0309518 |
| SEC24D | SEC24 family member D | -0.0308243 |
| COPA | coatomer protein complex, subunit alpha | -0.0307629 |
| SUCO | SUN domain containing ossification factor | -0.0307465 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0304927 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0304526 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0301451 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0300932 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0294524 |
| SPAG9 | sperm associated antigen 9 | -0.0292491 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0291963 |
| TMEM165 | transmembrane protein 165 | -0.0290751 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0290171 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | -0.0287738 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0286753 |
| FNDC3B | fibronectin type III domain containing 3B | -0.028654 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | -0.0284943 |
| ATF6 | activating transcription factor 6 | -0.0282781 |
| TMEM263 | transmembrane protein 263 | -0.0282165 |
| HM13 | histocompatibility (minor) 13 | -0.0281702 |
| HMGA1 | high mobility group AT-hook 1 | -0.0281701 |
| RPS8 | ribosomal protein S8 | -0.0281038 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0280349 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0279768 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0278866 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0277687 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0276287 |
| MYADM | myeloid-associated differentiation marker | -0.0275882 |
| TRAM1 | translocation associated membrane protein 1 | -0.0274154 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0268509 |
| CADM1 | cell adhesion molecule 1 | -0.02679 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0265571 |
| DGKI | diacylglycerol kinase, iota | -0.0264361 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0261954 |
| MSR1 | macrophage scavenger receptor 1 | -0.0260907 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0259347 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0258119 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0257228 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0255872 |
| MYO1E | myosin IE | -0.0253723 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0249872 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0249563 |
| SEC24A | SEC24 family member A | -0.0248239 |
| SEMA4A | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A | -0.0247045 |
| SCFD2 | sec1 family domain containing 2 | -0.0246302 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0244719 |
| RND3 | Rho family GTPase 3 | -0.0242659 |
