| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in A549 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_A549 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.186062 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.159156 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.139598 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.138013 |
| SMAD3 | SMAD family member 3 | 0.125369 |
| TMSB10 | thymosin beta 10 | 0.115976 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0980261 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0962597 |
| PLEC | plectin | 0.0925915 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0882266 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0871214 |
| MSN | moesin | 0.0868333 |
| NAV2 | neuron navigator 2 | 0.0809012 |
| MCL1 | myeloid cell leukemia 1 | 0.0766988 |
| NONO | non-POU domain containing, octamer-binding | 0.0763412 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0720353 |
| RPL23 | ribosomal protein L23 | 0.0717053 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.071436 |
| RPL3 | ribosomal protein L3 | 0.069164 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0671999 |
| ACTG1 | actin gamma 1 | 0.0636725 |
| FLNA | filamin A, alpha | 0.0610275 |
| KRT8 | keratin 8, type II | 0.060549 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0602427 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.060025 |
| MT2A | metallothionein 2A | 0.0594833 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0564205 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0563936 |
| ASPH | aspartate beta-hydroxylase | 0.0560178 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0560162 |
| MT1X | metallothionein 1X | 0.0552794 |
| KRT18 | keratin 18, type I | 0.0534263 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0520008 |
| POTEF | POTE ankyrin domain family, member F | 0.0496832 |
| PKM | pyruvate kinase, muscle | 0.0491654 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0484653 |
| PCBP2 | poly(rC) binding protein 2 | 0.0484642 |
| PFN1 | profilin 1 | 0.048156 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0462101 |
| KIRREL3 | kin of IRRE like 3 (Drosophila) | 0.045286 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0445953 |
| KRT7 | keratin 7, type II | 0.0438317 |
| RPS19 | ribosomal protein S19 | 0.0427409 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0424918 |
| CTBP2 | C-terminal binding protein 2 | 0.0419451 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.041631 |
| ACTN4 | actinin, alpha 4 | 0.0406172 |
| PTK2 | protein tyrosine kinase 2 | 0.0405157 |
| TMSB4X | thymosin beta 4, X-linked | 0.0402625 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0396088 |
| FLNB | filamin B, beta | 0.0393857 |
| RPL11 | ribosomal protein L11 | 0.0393538 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0392562 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0387311 |
| MINK1 | misshapen-like kinase 1 | 0.0381691 |
| EGR1 | early growth response 1 | 0.0372336 |
| NUP58 | nucleoporin 58 | 0.0371855 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0369402 |
| ECT2 | epithelial cell transforming 2 | 0.0365516 |
| SPAG9 | sperm associated antigen 9 | 0.0358786 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0358565 |
| BCL2L1 | BCL2-like 1 | 0.0349143 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0348537 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0348476 |
| ANXA1 | annexin A1 | 0.0345815 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0345682 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0339862 |
| SEPTIN9 | septin 9 | 0.0335155 |
| TBC1D22A | TBC1 domain family, member 22A | 0.033194 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0331123 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0328543 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0326863 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0326342 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0324978 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0324278 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0323989 |
| RLIM | ring finger protein, LIM domain interacting | 0.0320155 |
| VCL | vinculin | 0.031909 |
| RPL13A | ribosomal protein L13a | 0.0316514 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0314433 |
| LMNA | lamin A/C | 0.0309574 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0308009 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0307938 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0306544 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0304817 |
| CMIP | c-Maf inducing protein | 0.030465 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0302416 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0299958 |
| MYO10 | myosin X | 0.0299124 |
| PGK1 | phosphoglycerate kinase 1 | 0.0297296 |
| RPL7 | ribosomal protein L7 | 0.0296855 |
| PMM2 | phosphomannomutase 2 | 0.0295613 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0295008 |
| WDR43 | WD repeat domain 43 | 0.0293099 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0289319 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0287786 |
| ACTN1 | actinin, alpha 1 | 0.0286552 |
| STEAP3 | STEAP family member 3, metalloreductase | 0.0286105 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0286007 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0285674 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.176594 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0960307 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0725867 |
| EFNA5 | ephrin-A5 | -0.0642605 |
| VIM | vimentin | -0.0616388 |
| RAI14 | retinoic acid induced 14 | -0.0583485 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.057786 |
| CA12 | carbonic anhydrase XII | -0.0565013 |
| OSMR | oncostatin M receptor | -0.05604 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0541896 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | -0.0532715 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.053265 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.049737 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.049291 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0464106 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0463217 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0452471 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0429105 |
| RIGI | RNA sensor RIG-I | -0.0402316 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0401566 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0336589 |
| ANXA4 | annexin A4 | -0.0324853 |
| RRBP1 | ribosome binding protein 1 | -0.031809 |
| RIN2 | Ras and Rab interactor 2 | -0.0313495 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0303553 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0299831 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0295732 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0292864 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0291865 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.028524 |
| NRP1 | neuropilin 1 | -0.025465 |
| HIP1 | huntingtin interacting protein 1 | -0.0252334 |
| MYO9A | myosin IXA | -0.0250588 |
| IER3 | immediate early response 3 | -0.025022 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0249837 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0241476 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0240625 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.023969 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0235447 |
| EHBP1 | EH domain binding protein 1 | -0.022941 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0229115 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0227548 |
| PLSCR1 | phospholipid scramblase 1 | -0.0227019 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0225483 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0218043 |
| BMERB1 | bMERB domain containing 1 | -0.0214547 |
| CD99 | CD99 molecule | -0.0214148 |
| CANX | calnexin | -0.021393 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0212916 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0208961 |
| GPRIN3 | GPRIN family member 3 | -0.0207821 |
| NF1 | neurofibromin 1 | -0.0206044 |
| CP | ceruloplasmin (ferroxidase) | -0.0205577 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.020491 |
| EGFR | epidermal growth factor receptor | -0.0203665 |
| DUSP16 | dual specificity phosphatase 16 | -0.0203475 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0203346 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0202177 |
| ZNF638 | zinc finger protein 638 | -0.0199523 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0198866 |
| NDRG1 | N-myc downstream regulated 1 | -0.0198224 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0198141 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0196164 |
| CLDN1 | claudin 1 | -0.0193599 |
| FN1 | fibronectin 1 | -0.019251 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0190802 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0189091 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0188916 |
| BICC1 | BicC family RNA binding protein 1 | -0.0187852 |
| HLA-E | major histocompatibility complex, class I, E | -0.0184502 |
| MYO1E | myosin IE | -0.0184378 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0183609 |
| HGSNAT | heparan-alpha-glucosaminide N-acetyltransferase | -0.0183517 |
| TDRD7 | tudor domain containing 7 | -0.0182754 |
| GPATCH8 | G patch domain containing 8 | -0.0182633 |
| RPS29 | ribosomal protein S29 | -0.0180663 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.018021 |
| GOSR1 | golgi SNAP receptor complex member 1 | -0.0179367 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0179102 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0179097 |
| MAP4 | microtubule-associated protein 4 | -0.0178488 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0177819 |
| PDE10A | phosphodiesterase 10A | -0.0176279 |
| EXOC6B | exocyst complex component 6B | -0.0175604 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0173367 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | -0.0173261 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0173133 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0172539 |
| JMJD1C | jumonji domain containing 1C | -0.0171381 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0168862 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0167828 |
| RPL38 | ribosomal protein L38 | -0.0167662 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0167024 |
| SERPINB9 | serpin peptidase inhibitor, clade B (ovalbumin), member 9 | -0.0166717 |
| RAB1A | RAB1A, member RAS oncogene family | -0.016647 |
| RSPO3 | R-spondin 3 | -0.0165687 |
| KRT81 | keratin 81, type II | -0.0165386 |
| DNAAF9 | dynein axonemal assembly factor 9 | -0.016472 |
| MTDH | metadherin | -0.0163225 |
| GNAS | GNAS complex locus | -0.0162695 |
