| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in AN3 CA cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_AN3 CA drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.145403 |
| VEGFA | vascular endothelial growth factor A | 0.129208 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.105242 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0958078 |
| MEST | mesoderm specific transcript | 0.0874167 |
| RPL3 | ribosomal protein L3 | 0.0754832 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0685175 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0634776 |
| COL1A2 | collagen, type I, alpha 2 | 0.0609049 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0594913 |
| SFTPA2 | surfactant protein A2 | 0.0501292 |
| DBN1 | drebrin 1 | 0.0491743 |
| NONO | non-POU domain containing, octamer-binding | 0.0486106 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0481954 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0455474 |
| CALR | calreticulin | 0.045194 |
| MGP | matrix Gla protein | 0.0412012 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0399864 |
| NCOR2 | nuclear receptor corepressor 2 | 0.039826 |
| CAPRIN1 | cell cycle associated protein 1 | 0.0390041 |
| RPL4 | ribosomal protein L4 | 0.0385572 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0378843 |
| KAZN | kazrin, periplakin interacting protein | 0.0375089 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0365021 |
| RBM39 | RNA binding motif protein 39 | 0.036489 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0346989 |
| GSE1 | Gse1 coiled-coil protein | 0.0339443 |
| H1-2 | H1.2 linker histone, cluster member | 0.0335867 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0335774 |
| H1-4 | H1.4 linker histone, cluster member | 0.0335494 |
| FGFR2 | fibroblast growth factor receptor 2 | 0.033376 |
| RPS4X | ribosomal protein S4, X-linked | 0.0327417 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0327124 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0323393 |
| DOCK1 | dedicator of cytokinesis 1 | 0.0315925 |
| FUS | FUS RNA binding protein | 0.0314958 |
| CEP250 | centrosomal protein 250kDa | 0.0313886 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0307189 |
| SET | SET nuclear proto-oncogene | 0.0306926 |
| PLEC | plectin | 0.0305835 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0303222 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0300181 |
| BCOR | BCL6 corepressor | 0.0298787 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0298574 |
| RACK1 | receptor for activated C kinase 1 | 0.0297998 |
| HYOU1 | hypoxia up-regulated 1 | 0.0295284 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0292265 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0291785 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0290225 |
| OGA | O-GlcNAcase | 0.0289708 |
| RBM33 | RNA binding motif protein 33 | 0.0288134 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0273473 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0272071 |
| HOXC6 | homeobox C6 | 0.0270659 |
| CHD3 | chromodomain helicase DNA binding protein 3 | 0.0269384 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0264614 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0262289 |
| HSPA8 | heat shock 70kDa protein 8 | 0.02611 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0260381 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0260105 |
| INCENP | inner centromere protein antigens 135/155kDa | 0.0259376 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0256522 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0253511 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0253388 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0251504 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0250752 |
| ATG5 | autophagy related 5 | 0.0249758 |
| PNN | pinin, desmosome associated protein | 0.0249437 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.024833 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0246978 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0244654 |
| RPL13A | ribosomal protein L13a | 0.0244348 |
| HOXA3 | homeobox A3 | 0.0236613 |
| PLCG1 | phospholipase C, gamma 1 | 0.0234564 |
| SGCE | sarcoglycan, epsilon | 0.023051 |
| SMARCA1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 1 | 0.0230249 |
| PER1 | period circadian clock 1 | 0.022993 |
| TUBB | tubulin, beta class I | 0.0229709 |
| SPAG5 | sperm associated antigen 5 | 0.0229487 |
| TP53BP1 | tumor protein p53 binding protein 1 | 0.0225943 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0225931 |
| CNN3 | calponin 3, acidic | 0.0225024 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0223987 |
| EYA1 | EYA transcriptional coactivator and phosphatase 1 | 0.0223681 |
| SNX3 | sorting nexin 3 | 0.0223559 |
| MINK1 | misshapen-like kinase 1 | 0.0222728 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0220123 |
| RPL37 | ribosomal protein L37 | 0.0217731 |
| GTF3C1 | general transcription factor IIIC, polypeptide 1, alpha 220kDa | 0.0217355 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0216681 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0216403 |
| FAM120B | family with sequence similarity 120B | 0.0214926 |
| SEPTIN2 | septin 2 | 0.0213348 |
| SPTY2D1 | SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae) | 0.0213045 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0212546 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0212472 |
| SQSTM1 | sequestosome 1 | 0.0212046 |
| RPL11 | ribosomal protein L11 | 0.021156 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0210045 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0208817 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.201986 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.173055 |
| HMGA2 | high mobility group AT-hook 2 | -0.11047 |
| VIM | vimentin | -0.0924173 |
| CADM2 | cell adhesion molecule 2 | -0.0893967 |
| JMJD1C | jumonji domain containing 1C | -0.0854964 |
| IER3 | immediate early response 3 | -0.0725562 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0680399 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0638828 |
| IGF2 | insulin-like growth factor 2 | -0.0610391 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0582186 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0565546 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0563925 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0543956 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0486949 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0473361 |
| MYOF | myoferlin | -0.0468589 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0461571 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0457408 |
| SBF2 | SET binding factor 2 | -0.044906 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0445715 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0442097 |
| HMGA1 | high mobility group AT-hook 1 | -0.0430314 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0420314 |
| RPS6 | ribosomal protein S6 | -0.0418983 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0416844 |
| TULP4 | tubby like protein 4 | -0.040566 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0404135 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0402944 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.039485 |
| CDK13 | cyclin-dependent kinase 13 | -0.0387046 |
| BMPR1A | bone morphogenetic protein receptor, type IA | -0.0385773 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0383874 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0372169 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0357158 |
| CBFB | core-binding factor, beta subunit | -0.0347596 |
| PHF3 | PHD finger protein 3 | -0.0337598 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0336901 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0336238 |
| HMGB1 | high mobility group box 1 | -0.0329709 |
| CCNI | cyclin I | -0.0328484 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0323482 |
| FBXO11 | F-box protein 11 | -0.0321482 |
| PARD3 | par-3 family cell polarity regulator | -0.0317482 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0314394 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0309963 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0309553 |
| CENPF | centromere protein F, 350/400kDa | -0.0305362 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0304707 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | -0.0302062 |
| WASF2 | WAS protein family, member 2 | -0.0302043 |
| INTS6 | integrator complex subunit 6 | -0.0299202 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | -0.0297399 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0295593 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0292964 |
| CTBP2 | C-terminal binding protein 2 | -0.0291049 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0290102 |
| MAP4 | microtubule-associated protein 4 | -0.0289104 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0285868 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0284105 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0283481 |
| ZNF207 | zinc finger protein 207 | -0.027985 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0276811 |
| RPS23 | ribosomal protein S23 | -0.0275121 |
| CDK6 | cyclin-dependent kinase 6 | -0.027466 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0271601 |
| COL5A2 | collagen, type V, alpha 2 | -0.0271485 |
| USP15 | ubiquitin specific peptidase 15 | -0.0271323 |
| WAC | WW domain containing adaptor with coiled-coil | -0.027105 |
| AK1 | adenylate kinase 1 | -0.0270069 |
| RSF1 | remodeling and spacing factor 1 | -0.0269749 |
| TCF12 | transcription factor 12 | -0.0267681 |
| RPS8 | ribosomal protein S8 | -0.0267522 |
| FBXW7 | F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase | -0.026699 |
| ZFR | zinc finger RNA binding protein | -0.0266778 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0264921 |
| TET1 | tet methylcytosine dioxygenase 1 | -0.0263815 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0262066 |
| ADIPOR2 | adiponectin receptor 2 | -0.0261794 |
| CENPE | centromere protein E, 312kDa | -0.0259273 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0258768 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0258622 |
| TUT4 | terminal uridylyl transferase 4 | -0.025748 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0257094 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0256497 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0256455 |
| USP47 | ubiquitin specific peptidase 47 | -0.025517 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.025469 |
| CUX1 | cut-like homeobox 1 | -0.0254557 |
| CDC73 | cell division cycle 73 | -0.0253592 |
| ANO6 | anoctamin 6 | -0.0253456 |
| KLHL24 | kelch-like family member 24 | -0.0251072 |
| EFNA5 | ephrin-A5 | -0.0250938 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0250386 |
| MICU1 | mitochondrial calcium uptake 1 | -0.0250251 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0246996 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0246177 |
| RREB1 | ras responsive element binding protein 1 | -0.0245591 |
| RANBP17 | RAN binding protein 17 | -0.0244721 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0244187 |
