| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in AsPC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_AsPC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.205216 |
| FLNB | filamin B, beta | 0.179145 |
| PLEC | plectin | 0.163289 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0978394 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0968581 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0960639 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.079042 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0776663 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0761288 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | 0.0660921 |
| SDC4 | syndecan 4 | 0.0657972 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0598129 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0593081 |
| EZR | ezrin | 0.0589146 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0583516 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0578358 |
| TMSB10 | thymosin beta 10 | 0.0571203 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0564783 |
| FAM107B | family with sequence similarity 107, member B | 0.0559503 |
| KRT8 | keratin 8, type II | 0.0550946 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0543408 |
| SMAD3 | SMAD family member 3 | 0.0529989 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0518928 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0516544 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0466358 |
| ITGA6 | integrin, alpha 6 | 0.0458281 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0424673 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0395147 |
| FOSL1 | FOS-like antigen 1 | 0.0387916 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0384857 |
| HRNR | hornerin | 0.0382931 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0378355 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0373874 |
| MXD1 | MAX dimerization protein 1 | 0.0355444 |
| ITGB4 | integrin, beta 4 | 0.03512 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0350883 |
| GUK1 | guanylate kinase 1 | 0.0342582 |
| NONO | non-POU domain containing, octamer-binding | 0.0332536 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0332139 |
| NPTN | neuroplastin | 0.0331682 |
| RPL3 | ribosomal protein L3 | 0.0323492 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0322786 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0321626 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0319855 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0312396 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0304126 |
| CORO1C | coronin, actin binding protein, 1C | 0.0295132 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0288904 |
| SPAG9 | sperm associated antigen 9 | 0.0287503 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0283611 |
| TGM2 | transglutaminase 2 | 0.0281059 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.028062 |
| ANXA11 | annexin A11 | 0.0280367 |
| OPTN | optineurin | 0.027771 |
| OGA | O-GlcNAcase | 0.0270253 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0269508 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0268073 |
| FAM13A | family with sequence similarity 13, member A | 0.0264283 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0263176 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0262146 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0249364 |
| TMSB4X | thymosin beta 4, X-linked | 0.024831 |
| TNFRSF6B | tumor necrosis factor receptor superfamily, member 6b, decoy | 0.0246172 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0236058 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0235878 |
| HPCAL1 | hippocalcin-like 1 | 0.0234828 |
| ARRDC3 | arrestin domain containing 3 | 0.023465 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0231507 |
| USP3 | ubiquitin specific peptidase 3 | 0.02288 |
| PGK1 | phosphoglycerate kinase 1 | 0.0226813 |
| ATP13A3 | ATPase type 13A3 | 0.0226736 |
| EPHA2 | EPH receptor A2 | 0.0222628 |
| AFDN | afadin, adherens junction formation factor | 0.0222064 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0217913 |
| LMTK2 | lemur tyrosine kinase 2 | 0.0217423 |
| FAM3C | family with sequence similarity 3, member C | 0.0215709 |
| CAPRIN2 | caprin family member 2 | 0.0215583 |
| RASA3 | RAS p21 protein activator 3 | 0.0213449 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0212221 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0211841 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0210779 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0209252 |
| ADM | adrenomedullin | 0.0209114 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0209107 |
| CARHSP1 | calcium regulated heat stable protein 1, 24kDa | 0.0208599 |
| SDC1 | syndecan 1 | 0.0207988 |
| CD9 | CD9 molecule | 0.0207885 |
| SERTAD2 | SERTA domain containing 2 | 0.0205263 |
| TPM3 | tropomyosin 3 | 0.0203619 |
| TPD52L2 | tumor protein D52-like 2 | 0.0203358 |
| APP | amyloid beta (A4) precursor protein | 0.0200964 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0200337 |
| ACTN4 | actinin, alpha 4 | 0.0200198 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0199802 |
| RPL23 | ribosomal protein L23 | 0.0199527 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0198752 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0197807 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0197665 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0196637 |
| CCNY | cyclin Y | 0.0196473 |
| Symbol | Name | Standardized Value |
|---|---|---|
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.11907 |
| EGFR | epidermal growth factor receptor | -0.0958985 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0942651 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0917518 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0836707 |
| LMO7 | LIM domain 7 | -0.0790478 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0766034 |
| NPSR1 | neuropeptide S receptor 1 | -0.0744089 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0722025 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0709945 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0683636 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0681001 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0653884 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0645388 |
| RASAL2 | RAS protein activator like 2 | -0.0622117 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0606695 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0605373 |
| DHRS9 | dehydrogenase/reductase (SDR family) member 9 | -0.0574757 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0538813 |
| ARPC1A | actin related protein 2/3 complex, subunit 1A, 41kDa | -0.0534419 |
| MUC17 | mucin 17, cell surface associated | -0.0514366 |
| EHBP1 | EH domain binding protein 1 | -0.0508842 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0508499 |
| CDK13 | cyclin-dependent kinase 13 | -0.049803 |
| HMGA1 | high mobility group AT-hook 1 | -0.0485178 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.0468473 |
| CD2AP | CD2-associated protein | -0.0461558 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0459754 |
| HMGA2 | high mobility group AT-hook 2 | -0.0455446 |
| TXNRD1 | thioredoxin reductase 1 | -0.0454413 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0443708 |
| DIAPH2 | diaphanous-related formin 2 | -0.0442198 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0438189 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0428022 |
| FBXO11 | F-box protein 11 | -0.0427357 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0423138 |
| VIM | vimentin | -0.0422679 |
| RALGPS2 | Ral GEF with PH domain and SH3 binding motif 2 | -0.0413394 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0389302 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0386943 |
| TAOK3 | TAO kinase 3 | -0.0377304 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0375554 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0370456 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0365619 |
| EFNA5 | ephrin-A5 | -0.0359774 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.035678 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0354154 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0351291 |
| JMJD1C | jumonji domain containing 1C | -0.0348525 |
| LAMA4 | laminin, alpha 4 | -0.0347788 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0345135 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | -0.0344124 |
| SP100 | SP100 nuclear antigen | -0.0338692 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0336837 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0332522 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0328856 |
| VMP1 | vacuole membrane protein 1 | -0.0328075 |
| ANXA2 | annexin A2 | -0.0325519 |
| SVIL | supervillin | -0.0323999 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.032374 |
| INTS6 | integrator complex subunit 6 | -0.0322556 |
| HDAC9 | histone deacetylase 9 | -0.0321794 |
| GOLGB1 | golgin B1 | -0.0321044 |
| CLMP | CXADR-like membrane protein | -0.0319705 |
| VCAN | versican | -0.0316514 |
| COG5 | component of oligomeric golgi complex 5 | -0.0315853 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0315071 |
| PRSS3 | protease, serine, 3 | -0.0314798 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.031362 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0313274 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0312084 |
| PRELID2 | PRELI domain containing 2 | -0.0310615 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0310226 |
| CANX | calnexin | -0.0301559 |
| USP34 | ubiquitin specific peptidase 34 | -0.0300536 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0295778 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0295377 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0292659 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0291951 |
| MCU | mitochondrial calcium uniporter | -0.0288538 |
| NBEAL1 | neurobeachin-like 1 | -0.0286896 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0286326 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0286167 |
| RAB10 | RAB10, member RAS oncogene family | -0.0286123 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0281598 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0279551 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0279425 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0277969 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0272156 |
| MYOF | myoferlin | -0.0271955 |
| OXR1 | oxidation resistance 1 | -0.0270555 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0266207 |
| USP15 | ubiquitin specific peptidase 15 | -0.0262977 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0257219 |
| NABP1 | nucleic acid binding protein 1 | -0.0256917 |
| TMEM263 | transmembrane protein 263 | -0.0256397 |
| TRRAP | transformation/transcription domain-associated protein | -0.0254229 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0253523 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0253018 |
| PMM2 | phosphomannomutase 2 | -0.0253005 |
