| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in BT-474 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_BT-474 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPL23 | ribosomal protein L23 | 0.187643 |
| CEP250 | centrosomal protein 250kDa | 0.125189 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.108275 |
| RPL19 | ribosomal protein L19 | 0.0782472 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0777873 |
| VEGFA | vascular endothelial growth factor A | 0.0761042 |
| MLLT6 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6 | 0.0734515 |
| LASP1 | LIM and SH3 protein 1 | 0.0728033 |
| KRT8 | keratin 8, type II | 0.0723083 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0719019 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0705573 |
| PLEC | plectin | 0.0656568 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0628579 |
| SET | SET nuclear proto-oncogene | 0.0614031 |
| NDRG1 | N-myc downstream regulated 1 | 0.0609403 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0597922 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | 0.0582086 |
| TMSB4X | thymosin beta 4, X-linked | 0.0547273 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0540434 |
| ACSS2 | acyl-CoA synthetase short-chain family member 2 | 0.0521204 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0513099 |
| KRT18 | keratin 18, type I | 0.0489659 |
| ACTG1 | actin gamma 1 | 0.0487891 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0456754 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0410484 |
| PTMA | prothymosin, alpha | 0.0405809 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0388627 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0378186 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0361539 |
| SRCIN1 | SRC kinase signaling inhibitor 1 | 0.0360013 |
| LMNA | lamin A/C | 0.0351797 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0351379 |
| RPL3 | ribosomal protein L3 | 0.0339572 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0327713 |
| NONO | non-POU domain containing, octamer-binding | 0.0326861 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.032202 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0316533 |
| HRNR | hornerin | 0.0313914 |
| RPS3 | ribosomal protein S3 | 0.031309 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0310611 |
| KIF1A | kinesin family member 1A | 0.0308581 |
| HLA-C | major histocompatibility complex, class I, C | 0.0303994 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0297848 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0295921 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0291489 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | 0.0290501 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0290389 |
| MLPH | melanophilin | 0.0290347 |
| PNN | pinin, desmosome associated protein | 0.0290184 |
| B2M | beta-2-microglobulin | 0.0281259 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0280545 |
| PPP1R9B | protein phosphatase 1, regulatory subunit 9B | 0.027955 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0274137 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0270361 |
| TPM3 | tropomyosin 3 | 0.0270229 |
| HLA-B | major histocompatibility complex, class I, B | 0.0269422 |
| INSIG1 | insulin induced gene 1 | 0.0266436 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0261809 |
| CCNY | cyclin Y | 0.0260791 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0254085 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0253807 |
| RPL35A | ribosomal protein L35a | 0.0250573 |
| FLNA | filamin A, alpha | 0.0246972 |
| CWC25 | CWC25 spliceosome-associated protein homolog (S. cerevisiae) | 0.0244161 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0241808 |
| MINK1 | misshapen-like kinase 1 | 0.0241498 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0241207 |
| GOLGA2 | golgin A2 | 0.0239512 |
| EPPK1 | epiplakin 1 | 0.0236124 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.023437 |
| STIP1 | stress-induced phosphoprotein 1 | 0.02318 |
| TPD52 | tumor protein D52 | 0.0231686 |
| FAM13A | family with sequence similarity 13, member A | 0.0230974 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0230052 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0228131 |
| ACTN1 | actinin, alpha 1 | 0.0227789 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0227113 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0227008 |
| DSPP | dentin sialophosphoprotein | 0.0219496 |
| PFKP | phosphofructokinase, platelet | 0.0219411 |
| CALR | calreticulin | 0.0218714 |
| STARD3 | StAR-related lipid transfer (START) domain containing 3 | 0.0217082 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0216696 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0216325 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0214814 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0214053 |
| KRT7 | keratin 7, type II | 0.0213634 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0213464 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.0212805 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0212805 |
| MKRN1 | makorin ring finger protein 1 | 0.0210215 |
| ARGLU1 | arginine and glutamate rich 1 | 0.020789 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0205984 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0204079 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0201567 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | 0.0197481 |
| TP53INP2 | tumor protein p53 inducible nuclear protein 2 | 0.0196588 |
| SMARCA4 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 | 0.0196351 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0195846 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0195372 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.15306 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0980737 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0786456 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0669289 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0646258 |
| CDK12 | cyclin-dependent kinase 12 | -0.0646242 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0600124 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0481872 |
| CCNI | cyclin I | -0.0469956 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0467994 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0449111 |
| ZNF217 | zinc finger protein 217 | -0.0436792 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0431531 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0411946 |
| NF1 | neurofibromin 1 | -0.0396876 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.03952 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0387347 |
| CCND1 | cyclin D1 | -0.0382683 |
| ASPH | aspartate beta-hydroxylase | -0.037124 |
| MAPK8 | mitogen-activated protein kinase 8 | -0.0367713 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0367567 |
| EXOC4 | exocyst complex component 4 | -0.0364205 |
| S100A9 | S100 calcium binding protein A9 | -0.0364096 |
| SERPINB4 | serpin peptidase inhibitor, clade B (ovalbumin), member 4 | -0.0363784 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0335123 |
| TC2N | tandem C2 domains, nuclear | -0.0333265 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0322279 |
| EFNA5 | ephrin-A5 | -0.032175 |
| UBC | ubiquitin C | -0.0319365 |
| VMP1 | vacuole membrane protein 1 | -0.0312047 |
| TMEM123 | transmembrane protein 123 | -0.0308383 |
| OSMR | oncostatin M receptor | -0.0305969 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0304301 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0304298 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0304174 |
| RARRES1 | retinoic acid receptor responder (tazarotene induced) 1 | -0.029877 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0296875 |
| SLFN5 | schlafen family member 5 | -0.0289266 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0288024 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0287628 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.027985 |
| BPTF | bromodomain PHD finger transcription factor | -0.0279662 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0278603 |
| AHNAK | AHNAK nucleoprotein | -0.0278114 |
| MT2A | metallothionein 2A | -0.0275655 |
| INTS6 | integrator complex subunit 6 | -0.0274082 |
| MAP4 | microtubule-associated protein 4 | -0.0270579 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0269174 |
| GLCCI1 | glucocorticoid induced 1 | -0.0266866 |
| PARD3 | par-3 family cell polarity regulator | -0.0266187 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0258782 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0253322 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.025199 |
| JMJD1C | jumonji domain containing 1C | -0.024739 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0247199 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0244107 |
| CANX | calnexin | -0.02434 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0241109 |
| SMYD3 | SET and MYND domain containing 3 | -0.0240336 |
| SBF2 | SET binding factor 2 | -0.0239994 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0238924 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0236588 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0235247 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0232605 |
| TCN1 | transcobalamin I (vitamin B12 binding protein, R binder family) | -0.0231888 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0229472 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0228863 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0226395 |
| ATF6 | activating transcription factor 6 | -0.0225607 |
| IL1RAPL2 | interleukin 1 receptor accessory protein-like 2 | -0.0225594 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0224919 |
| STXBP4 | syntaxin binding protein 4 | -0.0224851 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0223253 |
| SCFD1 | sec1 family domain containing 1 | -0.0221904 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0219061 |
| CDK13 | cyclin-dependent kinase 13 | -0.0218358 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0217961 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0217817 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0215241 |
| USP34 | ubiquitin specific peptidase 34 | -0.0212964 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0212683 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0211858 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0211105 |
| NTN4 | netrin 4 | -0.0210875 |
| SERPINB3 | serpin peptidase inhibitor, clade B (ovalbumin), member 3 | -0.0210839 |
| S100A8 | S100 calcium binding protein A8 | -0.0210317 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0209712 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0209568 |
| STK4 | serine/threonine kinase 4 | -0.0209304 |
| OLA1 | Obg-like ATPase 1 | -0.0205256 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0205109 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0204393 |
| RPS6KB1 | ribosomal protein S6 kinase, 70kDa, polypeptide 1 | -0.0203163 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0202811 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0202503 |
| RNF19A | ring finger protein 19A, RBR E3 ubiquitin protein ligase | -0.0202446 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0202301 |
| GPHN | gephyrin | -0.0202226 |
| MYO6 | myosin VI | -0.0200421 |
| IER3 | immediate early response 3 | -0.0199902 |
