| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in C32 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_C32 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VGF | VGF nerve growth factor inducible | 0.160093 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.115356 |
| MT2A | metallothionein 2A | 0.105349 |
| LOC112694756 | uncharaterized LOC112694756 | 0.10349 |
| LEF1 | lymphoid enhancer-binding factor 1 | 0.101884 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0810524 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0724641 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0713185 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0661556 |
| RPL3 | ribosomal protein L3 | 0.0599932 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.058941 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0580826 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0575831 |
| TAGLN2 | transgelin 2 | 0.0567546 |
| FOSL1 | FOS-like antigen 1 | 0.0552242 |
| TMEM178B | transmembrane protein 178B | 0.0531662 |
| NDRG1 | N-myc downstream regulated 1 | 0.0524696 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0497718 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0490205 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0490002 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0473869 |
| TNNC1 | troponin C type 1 (slow) | 0.0470033 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0464529 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0460043 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0459121 |
| NAV2 | neuron navigator 2 | 0.0450869 |
| TMSB10 | thymosin beta 10 | 0.0442071 |
| ZYX | zyxin | 0.043934 |
| PKM | pyruvate kinase, muscle | 0.0420855 |
| SFTPA2 | surfactant protein A2 | 0.0418984 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0417302 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0416466 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.0412474 |
| CABIN1 | calcineurin binding protein 1 | 0.0407938 |
| CENPF | centromere protein F, 350/400kDa | 0.0404289 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0404205 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0385574 |
| DST | dystonin | 0.0381752 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0375893 |
| NONO | non-POU domain containing, octamer-binding | 0.0373134 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0367641 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0363837 |
| FBXO7 | F-box protein 7 | 0.0363339 |
| MKRN1 | makorin ring finger protein 1 | 0.0360322 |
| VEGFA | vascular endothelial growth factor A | 0.035396 |
| YBX1 | Y box binding protein 1 | 0.0347479 |
| SOX10 | SRY (sex determining region Y)-box 10 | 0.0343601 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0342517 |
| SETBP1 | SET binding protein 1 | 0.0338305 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0337886 |
| MT1X | metallothionein 1X | 0.0334997 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0333917 |
| CHSY1 | chondroitin sulfate synthase 1 | 0.0327174 |
| APP | amyloid beta (A4) precursor protein | 0.0326704 |
| FRMD6 | FERM domain containing 6 | 0.0326073 |
| CEP250 | centrosomal protein 250kDa | 0.0323156 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0316263 |
| MSN | moesin | 0.0314443 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0314089 |
| PGK1 | phosphoglycerate kinase 1 | 0.0307643 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0305746 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | 0.0296905 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0292545 |
| MED15 | mediator complex subunit 15 | 0.0292146 |
| AHR | aryl hydrocarbon receptor | 0.028793 |
| NBAS | neuroblastoma amplified sequence | 0.0286435 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0286176 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | 0.0281037 |
| HLA-C | major histocompatibility complex, class I, C | 0.0279938 |
| RNF145 | ring finger protein 145 | 0.0278672 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | 0.0278464 |
| DCT | dopachrome tautomerase | 0.0274623 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0270506 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0269103 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0268277 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0267244 |
| UBA1 | ubiquitin-like modifier activating enzyme 1 | 0.0263511 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.0263247 |
| ACTN1 | actinin, alpha 1 | 0.02615 |
| RBM33 | RNA binding motif protein 33 | 0.0259883 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | 0.0256342 |
| GALNT2 | polypeptide N-acetylgalactosaminyltransferase 2 | 0.0253497 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0252354 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0252153 |
| PLEC | plectin | 0.025133 |
| RNF213 | ring finger protein 213 | 0.0250539 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0248711 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.024565 |
| B2M | beta-2-microglobulin | 0.0244474 |
| FLNA | filamin A, alpha | 0.0243103 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0237281 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0235972 |
| WWP2 | WW domain containing E3 ubiquitin protein ligase 2 | 0.0235762 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0234084 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0230618 |
| NAV1 | neuron navigator 1 | 0.023016 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0228827 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.02261 |
| GAS7 | growth arrest-specific 7 | 0.0225028 |
| ENO1 | enolase 1, (alpha) | 0.0223206 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.411542 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.24792 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.115486 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0891281 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0883554 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0851207 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0671824 |
| GDF15 | growth differentiation factor 15 | -0.0660108 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0657499 |
| VIM | vimentin | -0.0633207 |
| MDGA2 | MAM domain containing glycosylphosphatidylinositol anchor 2 | -0.0570125 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0560567 |
| IFRD1 | interferon-related developmental regulator 1 | -0.0549525 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0531939 |
| IER3 | immediate early response 3 | -0.0522864 |
| NLGN1 | neuroligin 1 | -0.0514248 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0503966 |
| CANX | calnexin | -0.0480894 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0461913 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0449323 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0440978 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0432996 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.043273 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.0429309 |
| PTCHD4 | patched domain containing 4 | -0.0423632 |
| TMEM123 | transmembrane protein 123 | -0.0422252 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0415836 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0406379 |
| NPR2 | natriuretic peptide receptor 2 | -0.0400874 |
| CALU | calumenin | -0.0400257 |
| FN1 | fibronectin 1 | -0.0386974 |
| GPC6 | glypican 6 | -0.038018 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0377975 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0374102 |
| MYO1E | myosin IE | -0.0361361 |
| CUX1 | cut-like homeobox 1 | -0.0350484 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0341225 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0337492 |
| EHBP1 | EH domain binding protein 1 | -0.0326683 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0325499 |
| TRIM2 | tripartite motif containing 2 | -0.0322021 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0318533 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.031178 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0311373 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0309163 |
| VCL | vinculin | -0.0308538 |
| GNAS | GNAS complex locus | -0.0308332 |
| CCND1 | cyclin D1 | -0.0307832 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0306754 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.03046 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0302364 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0298618 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0294678 |
| TMEM263 | transmembrane protein 263 | -0.0288883 |
| JMJD1C | jumonji domain containing 1C | -0.028794 |
| SCFD2 | sec1 family domain containing 2 | -0.0279161 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0278598 |
| RYBP | RING1 and YY1 binding protein | -0.0275599 |
| SEC24A | SEC24 family member A | -0.0275581 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.027284 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0271983 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0271124 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0268082 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.0265037 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0263744 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0259705 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0259702 |
| ZNF704 | zinc finger protein 704 | -0.0258523 |
| MTDH | metadherin | -0.0258422 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.0257699 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0257648 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0257418 |
| PARVB | parvin, beta | -0.025402 |
| CTTNBP2 | cortactin binding protein 2 | -0.0253905 |
| HIP1 | huntingtin interacting protein 1 | -0.0253851 |
| MEF2A | myocyte enhancer factor 2A | -0.0249225 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.024268 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0241278 |
| RHEB | Ras homolog enriched in brain | -0.0240673 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0239032 |
| LRRC23 | leucine rich repeat containing 23 | -0.0237182 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0236951 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0236756 |
| BZW2 | basic leucine zipper and W2 domains 2 | -0.0233137 |
| GOLGA4 | golgin A4 | -0.0232873 |
| COG5 | component of oligomeric golgi complex 5 | -0.0232162 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0230099 |
| TLE4 | transducin-like enhancer of split 4 | -0.0229302 |
| GTF2B | general transcription factor IIB | -0.0227388 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0224743 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0223522 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0223176 |
| ODR4 | odr-4 GPCR localization factor homolog | -0.0221056 |
| MEIS2 | Meis homeobox 2 | -0.0220278 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0219507 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0218415 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | -0.0217514 |
| EMP1 | epithelial membrane protein 1 | -0.0216671 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0216256 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0214674 |
