| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in CFPAC-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_CFPAC-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.138522 |
| NDRG1 | N-myc downstream regulated 1 | 0.136245 |
| APOL1 | apolipoprotein L, 1 | 0.13453 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.124701 |
| LOC112694756 | uncharaterized LOC112694756 | 0.120123 |
| HLA-B | major histocompatibility complex, class I, B | 0.116509 |
| HLA-A | major histocompatibility complex, class I, A | 0.11416 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.106545 |
| SMAD3 | SMAD family member 3 | 0.105118 |
| TMSB4X | thymosin beta 4, X-linked | 0.0968116 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0910312 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0775887 |
| TGM2 | transglutaminase 2 | 0.0763394 |
| PLAU | plasminogen activator, urokinase | 0.0746066 |
| HLA-C | major histocompatibility complex, class I, C | 0.0706155 |
| VEGFA | vascular endothelial growth factor A | 0.0689052 |
| APP | amyloid beta (A4) precursor protein | 0.0684609 |
| B2M | beta-2-microglobulin | 0.0676915 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0664743 |
| PLEC | plectin | 0.0644415 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0600734 |
| KRT8 | keratin 8, type II | 0.0599134 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0579876 |
| LAMB3 | laminin, beta 3 | 0.0571004 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0564123 |
| PGK1 | phosphoglycerate kinase 1 | 0.0564016 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0563852 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0555398 |
| ANXA11 | annexin A11 | 0.0527596 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.052004 |
| APOL2 | apolipoprotein L, 2 | 0.0501732 |
| FLNB | filamin B, beta | 0.0463588 |
| RPL3 | ribosomal protein L3 | 0.0462849 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0444865 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0428441 |
| EZR | ezrin | 0.0421467 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0421096 |
| ANKRD11 | ankyrin repeat domain 11 | 0.041405 |
| LASP1 | LIM and SH3 protein 1 | 0.0391304 |
| PFKP | phosphofructokinase, platelet | 0.0383112 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0377993 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0376708 |
| OPTN | optineurin | 0.0375499 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0374926 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0373904 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0371218 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0370567 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0361044 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0359281 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0358607 |
| HPCAL1 | hippocalcin-like 1 | 0.0355609 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0353788 |
| NONO | non-POU domain containing, octamer-binding | 0.0352575 |
| BCL2L1 | BCL2-like 1 | 0.035093 |
| KRT19 | keratin 19, type I | 0.0350808 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0346913 |
| GRB10 | growth factor receptor-bound protein 10 | 0.034529 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0343306 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0341487 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.0337801 |
| CIB1 | calcium and integrin binding 1 (calmyrin) | 0.0337107 |
| MCL1 | myeloid cell leukemia 1 | 0.0336035 |
| ACTG1 | actin gamma 1 | 0.0329695 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0327803 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0326563 |
| ADAM8 | ADAM metallopeptidase domain 8 | 0.0323696 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0319519 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0314197 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0310261 |
| TMEM51 | transmembrane protein 51 | 0.0309879 |
| HRNR | hornerin | 0.030706 |
| MED15 | mediator complex subunit 15 | 0.030689 |
| CEP250 | centrosomal protein 250kDa | 0.0304313 |
| ENO1 | enolase 1, (alpha) | 0.0303126 |
| CD74 | CD74 molecule, major histocompatibility complex, class II invariant chain | 0.0297808 |
| JUN | jun proto-oncogene | 0.0296164 |
| CMIP | c-Maf inducing protein | 0.0294832 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0288511 |
| SPAG9 | sperm associated antigen 9 | 0.0287527 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0281993 |
| FOSL1 | FOS-like antigen 1 | 0.0279008 |
| MXD1 | MAX dimerization protein 1 | 0.0276971 |
| RPL4 | ribosomal protein L4 | 0.0273512 |
| BRD2 | bromodomain containing 2 | 0.0271559 |
| PKM | pyruvate kinase, muscle | 0.0271415 |
| LDHA | lactate dehydrogenase A | 0.0269097 |
| SEMA7A | semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group) | 0.0268303 |
| FLNA | filamin A, alpha | 0.0267119 |
| TINAGL1 | tubulointerstitial nephritis antigen-like 1 | 0.0266075 |
| DOCK5 | dedicator of cytokinesis 5 | 0.026448 |
| INSIG2 | insulin induced gene 2 | 0.0263929 |
| HLA-E | major histocompatibility complex, class I, E | 0.0261255 |
| WDR45B | WD repeat domain 45B | 0.026047 |
| CLMN | calmin (calponin-like, transmembrane) | 0.0259781 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0259447 |
| MUC1 | mucin 1, cell surface associated | 0.0257212 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0256522 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0255035 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0254266 |
| SEPTIN9 | septin 9 | 0.0252009 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.211027 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.192189 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.112016 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0728674 |
| ANXA2 | annexin A2 | -0.0672083 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0659225 |
| PTMA | prothymosin, alpha | -0.0621561 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0561084 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0540324 |
| HMGA1 | high mobility group AT-hook 1 | -0.0533144 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0503478 |
| MMP7 | matrix metallopeptidase 7 | -0.0491817 |
| FUT8 | fucosyltransferase 8 (alpha (1,6) fucosyltransferase) | -0.0473145 |
| FTL | ferritin, light polypeptide | -0.0464965 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0447808 |
| CANX | calnexin | -0.0403609 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0396107 |
| GNAS | GNAS complex locus | -0.0377986 |
| RPLP1 | ribosomal protein, large, P1 | -0.0373708 |
| H1-0 | H1.0 linker histone | -0.0359996 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0348418 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0344722 |
| AHNAK | AHNAK nucleoprotein | -0.0340967 |
| DTNA | dystrobrevin, alpha | -0.0338341 |
| EFNA5 | ephrin-A5 | -0.0338206 |
| DSG2 | desmoglein 2 | -0.0328003 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.032305 |
| LMO7 | LIM domain 7 | -0.0322744 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0319031 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0316475 |
| TXNIP | thioredoxin interacting protein | -0.0306064 |
| IER3 | immediate early response 3 | -0.0300845 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0298246 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0293518 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0292627 |
| ITGA6 | integrin, alpha 6 | -0.0292365 |
| EREG | epiregulin | -0.0287552 |
| TMEM263 | transmembrane protein 263 | -0.0283654 |
| TOP1 | topoisomerase (DNA) I | -0.0281374 |
| MAP1B | microtubule-associated protein 1B | -0.0279896 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.027502 |
| RTN4 | reticulon 4 | -0.027377 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0273334 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0270954 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0269625 |
| VIM | vimentin | -0.0268541 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0256241 |
| PARD3 | par-3 family cell polarity regulator | -0.0251899 |
| COG5 | component of oligomeric golgi complex 5 | -0.0248671 |
| CCNI | cyclin I | -0.0248073 |
| RPS24 | ribosomal protein S24 | -0.0246687 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.024495 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0244808 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.024318 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0242904 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.024172 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0241596 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0240779 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0235782 |
| NRP1 | neuropilin 1 | -0.023506 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0234857 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0234419 |
| TMEM123 | transmembrane protein 123 | -0.0233883 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0230473 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0229147 |
| NRG3 | neuregulin 3 | -0.0228704 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0227786 |
| YME1L1 | YME1-like 1 ATPase | -0.0224168 |
| RPS25 | ribosomal protein S25 | -0.0222545 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0220715 |
| RPL19 | ribosomal protein L19 | -0.0218245 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0217985 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0217809 |
| KYNU | kynureninase | -0.0216787 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0215337 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0213803 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0213548 |
| EIF2A | eukaryotic translation initiation factor 2A, 65kDa | -0.0212629 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0211366 |
| GPHN | gephyrin | -0.0209862 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0208312 |
| NEK7 | NIMA-related kinase 7 | -0.0207124 |
| NABP1 | nucleic acid binding protein 1 | -0.0206017 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0205963 |
| GOLGA4 | golgin A4 | -0.0205109 |
| SEC24A | SEC24 family member A | -0.0204516 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0204337 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0203606 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.0202027 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0201178 |
| USP34 | ubiquitin specific peptidase 34 | -0.0198351 |
| RPS6 | ribosomal protein S6 | -0.0192648 |
| PCDH7 | protocadherin 7 | -0.0190146 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0188389 |
| TCEA1 | transcription elongation factor A (SII), 1 | -0.0188254 |
| MT1X | metallothionein 1X | -0.018678 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0185287 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0184358 |
| SP100 | SP100 nuclear antigen | -0.0184297 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0183695 |
