| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FAM13A | family with sequence similarity 13, member A | 0.0823103 |
| CRH | corticotropin releasing hormone | 0.078738 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0681314 |
| MSI2 | musashi RNA-binding protein 2 | 0.0604609 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0545726 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0544474 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0535275 |
| MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 0.0528809 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0515278 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | 0.0502204 |
| LPIN1 | lipin 1 | 0.0500826 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0497361 |
| COL1A1 | collagen, type I, alpha 1 | 0.0460058 |
| HELZ | helicase with zinc finger | 0.0451528 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0445024 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0444845 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.043487 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0425749 |
| SEPTIN2 | septin 2 | 0.042081 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0417097 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0402909 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0396102 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0394343 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0382151 |
| WDR45B | WD repeat domain 45B | 0.0379554 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0372355 |
| RPL3 | ribosomal protein L3 | 0.035783 |
| NONO | non-POU domain containing, octamer-binding | 0.0355477 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0355218 |
| PTMA | prothymosin, alpha | 0.0354958 |
| BRD4 | bromodomain containing 4 | 0.0346578 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0340983 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0338465 |
| AOPEP | aminopeptidase O (putative) | 0.0337633 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0327205 |
| CCNY | cyclin Y | 0.032186 |
| RPL19 | ribosomal protein L19 | 0.0321382 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0308951 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0306018 |
| CEP250 | centrosomal protein 250kDa | 0.0305755 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.0305005 |
| APP | amyloid beta (A4) precursor protein | 0.0303438 |
| UBE2O | ubiquitin-conjugating enzyme E2O | 0.029824 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.029672 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | 0.0296463 |
| GNG2 | guanine nucleotide binding protein (G protein), gamma 2 | 0.0293868 |
| FNBP1 | formin binding protein 1 | 0.0291994 |
| FUS | FUS RNA binding protein | 0.0289386 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0289278 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0282084 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0282025 |
| LSAMP | limbic system-associated membrane protein | 0.0276901 |
| GNA13 | guanine nucleotide binding protein (G protein), alpha 13 | 0.0269722 |
| AFDN | afadin, adherens junction formation factor | 0.0269496 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0260563 |
| TBX2 | T-box 2 | 0.025957 |
| RPL23 | ribosomal protein L23 | 0.0256249 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0254584 |
| CASC3 | cancer susceptibility candidate 3 | 0.0254559 |
| COL18A1 | collagen, type XVIII, alpha 1 | 0.0254148 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | 0.0244436 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0243873 |
| MYH10 | myosin, heavy chain 10, non-muscle | 0.024378 |
| SEPTIN9 | septin 9 | 0.0242504 |
| RAD21 | RAD21 homolog (S. pombe) | 0.024103 |
| SCG2 | secretogranin II | 0.0239427 |
| HMGB2 | high mobility group box 2 | 0.0239396 |
| RPL35A | ribosomal protein L35a | 0.0238886 |
| CABIN1 | calcineurin binding protein 1 | 0.023863 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0236793 |
| PHIP | pleckstrin homology domain interacting protein | 0.0236697 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.023596 |
| H3-3B | H3.3 histone B | 0.0235054 |
| NRG1 | neuregulin 1 | 0.023478 |
| PIAS2 | protein inhibitor of activated STAT, 2 | 0.0233795 |
| RPL4 | ribosomal protein L4 | 0.0233758 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0232367 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0232191 |
| MMP2 | matrix metallopeptidase 2 | 0.0231494 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0231041 |
| ADAR | adenosine deaminase, RNA-specific | 0.0230428 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0230298 |
| NDRG1 | N-myc downstream regulated 1 | 0.0229492 |
| PLAT | plasminogen activator, tissue | 0.0229313 |
| TUBB | tubulin, beta class I | 0.0228777 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0228385 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0227988 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | 0.0226213 |
| HLA-C | major histocompatibility complex, class I, C | 0.0225076 |
| SON | SON DNA binding protein | 0.0222875 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0220759 |
| COLEC11 | collectin sub-family member 11 | 0.0220311 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0220297 |
| CADM1 | cell adhesion molecule 1 | 0.0218442 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0217786 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | 0.0215323 |
| USP36 | ubiquitin specific peptidase 36 | 0.0214943 |
| CENPF | centromere protein F, 350/400kDa | 0.02147 |
| RLIM | ring finger protein, LIM domain interacting | 0.0214551 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0214488 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.318512 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.205017 |
| VCL | vinculin | -0.167783 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.106474 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.102019 |
| IGF2 | insulin-like growth factor 2 | -0.101979 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0932761 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0817985 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0678516 |
| VMP1 | vacuole membrane protein 1 | -0.0631579 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0609143 |
| MCL1 | myeloid cell leukemia 1 | -0.0575051 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0545539 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0526416 |
| SYT1 | synaptotagmin I | -0.0525175 |
| JMJD1C | jumonji domain containing 1C | -0.0505551 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0499594 |
| TPM1 | tropomyosin 1 (alpha) | -0.0497481 |
| FN1 | fibronectin 1 | -0.0495149 |
| VIM | vimentin | -0.048386 |
| CANX | calnexin | -0.0455965 |
| TTC17 | tetratricopeptide repeat domain 17 | -0.0448199 |
| DPH6 | diphthamine biosynthesis 6 | -0.0423547 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0417188 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0406602 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0404734 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0388902 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0377673 |
| RPS23 | ribosomal protein S23 | -0.0377484 |
| EGR1 | early growth response 1 | -0.0360298 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | -0.0359199 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0358823 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0357746 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0356482 |
| RPS15 | ribosomal protein S15 | -0.0354678 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0345573 |
| POTEF | POTE ankyrin domain family, member F | -0.0335933 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0335369 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0334222 |
| GATA3 | GATA binding protein 3 | -0.0333724 |
| RPLP1 | ribosomal protein, large, P1 | -0.0329724 |
| RPL31 | ribosomal protein L31 | -0.0328403 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.032614 |
| TLE4 | transducin-like enhancer of split 4 | -0.0325394 |
| UNC5C | unc-5 homolog C (C. elegans) | -0.0323159 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0321838 |
| MYO1E | myosin IE | -0.0320707 |
| GOLGB1 | golgin B1 | -0.0320401 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0318328 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0312368 |
| EFNA5 | ephrin-A5 | -0.031095 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0308043 |
| ACTG1 | actin gamma 1 | -0.0307924 |
| GOLGA4 | golgin A4 | -0.0300837 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.029597 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0293223 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0293007 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0292519 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.028326 |
| EXT1 | exostosin glycosyltransferase 1 | -0.028278 |
| PAPOLA | poly(A) polymerase alpha | -0.0281285 |
| BPTF | bromodomain PHD finger transcription factor | -0.0280064 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0279704 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0278972 |
| ZNF638 | zinc finger protein 638 | -0.0275256 |
| LIMA1 | LIM domain and actin binding 1 | -0.0273274 |
| CD36 | CD36 molecule (thrombospondin receptor) | -0.0269206 |
| PLPP1 | phospholipid phosphatase 1 | -0.0268736 |
| NBEAL1 | neurobeachin-like 1 | -0.0266131 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0265357 |
| CUX1 | cut-like homeobox 1 | -0.026422 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0263638 |
| SQSTM1 | sequestosome 1 | -0.0262279 |
| GLCCI1 | glucocorticoid induced 1 | -0.0260846 |
| DSTN | destrin (actin depolymerizing factor) | -0.0260316 |
| PTEN | phosphatase and tensin homolog | -0.0259951 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0259177 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0256854 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0256019 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0255668 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0253423 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0252365 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0252064 |
| RAB3GAP2 | RAB3 GTPase activating protein subunit 2 (non-catalytic) | -0.0250398 |
| TPM4 | tropomyosin 4 | -0.0249658 |
| ADAMTS1 | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | -0.0247877 |
| CEP350 | centrosomal protein 350kDa | -0.0242112 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0241514 |
| RPLP2 | ribosomal protein, large, P2 | -0.0241363 |
| MEIS2 | Meis homeobox 2 | -0.0241325 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0235239 |
| GPC6 | glypican 6 | -0.0231595 |
| JPT1 | Jupiter microtubule associated homolog 1 | -0.0229833 |
| RPS5 | ribosomal protein S5 | -0.0227436 |
| PRKCA | protein kinase C, alpha | -0.0225132 |
| EIF5B | eukaryotic translation initiation factor 5B | -0.0224381 |
| DEK | DEK proto-oncogene | -0.0223157 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0223031 |
| AHR | aryl hydrocarbon receptor | -0.0222429 |
| MYO9A | myosin IXA | -0.0219276 |