| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.122568 |
| ARGLU1 | arginine and glutamate rich 1 | 0.10263 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0870099 |
| HLA-B | major histocompatibility complex, class I, B | 0.0819215 |
| MLPH | melanophilin | 0.0757926 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.075181 |
| PHF3 | PHD finger protein 3 | 0.074031 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0705809 |
| CALR | calreticulin | 0.0592766 |
| VEGFA | vascular endothelial growth factor A | 0.0589684 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0548644 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0540251 |
| DSPP | dentin sialophosphoprotein | 0.0500425 |
| APOL2 | apolipoprotein L, 2 | 0.049469 |
| APOL1 | apolipoprotein L, 1 | 0.0489973 |
| SMAD3 | SMAD family member 3 | 0.0478615 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0476616 |
| NDRG1 | N-myc downstream regulated 1 | 0.0473447 |
| HLA-C | major histocompatibility complex, class I, C | 0.0457693 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0448861 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.0439014 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0438651 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0436216 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0428922 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0409846 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0408134 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.0402288 |
| IFNGR1 | interferon gamma receptor 1 | 0.0400847 |
| NONO | non-POU domain containing, octamer-binding | 0.0399834 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0392216 |
| STYXL2 | serine/threonine/tyrosine interacting like 2 | 0.0385757 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0383785 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0377379 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0373355 |
| CGN | cingulin | 0.0360465 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0359169 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0357934 |
| GIGYF2 | GRB10 interacting GYF protein 2 | 0.0357551 |
| RPS6 | ribosomal protein S6 | 0.0357508 |
| MINK1 | misshapen-like kinase 1 | 0.0348485 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.034818 |
| RPL35A | ribosomal protein L35a | 0.0346009 |
| HDAC4 | histone deacetylase 4 | 0.0345354 |
| EFHD2 | EF-hand domain family, member D2 | 0.0343452 |
| PFKP | phosphofructokinase, platelet | 0.0343257 |
| ERCC5 | excision repair cross-complementation group 5 | 0.0340191 |
| SH3PXD2A | SH3 and PX domains 2A | 0.033602 |
| RPL23 | ribosomal protein L23 | 0.0335487 |
| OAS1 | 2'-5'-oligoadenylate synthetase 1, 40/46kDa | 0.0335474 |
| RPL37 | ribosomal protein L37 | 0.0332657 |
| FAT1 | FAT atypical cadherin 1 | 0.0330821 |
| TUFT1 | tuftelin 1 | 0.032759 |
| PRRC2C | proline-rich coiled-coil 2C | 0.031768 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0314332 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | 0.0314052 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0303739 |
| GOLGA2 | golgin A2 | 0.0300881 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0299801 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0296367 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.029634 |
| ADAR | adenosine deaminase, RNA-specific | 0.0295882 |
| RNF43 | ring finger protein 43 | 0.0294183 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0292249 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0289541 |
| APP | amyloid beta (A4) precursor protein | 0.0289057 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0287138 |
| RPL13A | ribosomal protein L13a | 0.0286488 |
| HLA-A | major histocompatibility complex, class I, A | 0.0285994 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0284674 |
| RPL4 | ribosomal protein L4 | 0.0283757 |
| RPL37A | ribosomal protein L37a | 0.0280275 |
| EPCAM | epithelial cell adhesion molecule | 0.0279934 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0279239 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0279142 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0274885 |
| DDX23 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 | 0.0274829 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0273826 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0273264 |
| CDK5RAP3 | CDK5 regulatory subunit associated protein 3 | 0.0271036 |
| RPL11 | ribosomal protein L11 | 0.0270903 |
| SET | SET nuclear proto-oncogene | 0.0270558 |
| KRT18 | keratin 18, type I | 0.0270026 |
| SLK | STE20-like kinase | 0.0269001 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.026604 |
| SFTPA2 | surfactant protein A2 | 0.0265042 |
| CMIP | c-Maf inducing protein | 0.0264734 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0264426 |
| KIF16B | kinesin family member 16B | 0.026407 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0263554 |
| PNPLA7 | patatin-like phospholipase domain containing 7 | 0.0262585 |
| ANXA11 | annexin A11 | 0.0262484 |
| RRBP1 | ribosome binding protein 1 | 0.026246 |
| OGA | O-GlcNAcase | 0.0260876 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0258817 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0258772 |
| DNM2 | dynamin 2 | 0.0257867 |
| MYO18A | myosin XVIIIA | 0.0256088 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0252387 |
| SDC4 | syndecan 4 | 0.025088 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0249595 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.164399 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0882993 |
| ERBIN | erbb2 interacting protein | -0.0828917 |
| PERP | PERP, TP53 apoptosis effector | -0.0820219 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0805157 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0652623 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0642891 |
| ANXA2 | annexin A2 | -0.0622284 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0584688 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0563017 |
| EGR1 | early growth response 1 | -0.0554388 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0552333 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.055161 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0535675 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0507297 |
| CCNL1 | cyclin L1 | -0.0491087 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0479471 |
| VCL | vinculin | -0.0470845 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.046649 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0465412 |
| FNIP1 | folliculin interacting protein 1 | -0.046107 |
| XAF1 | XIAP associated factor 1 | -0.0444185 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0442444 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0435326 |
| ZNF292 | zinc finger protein 292 | -0.0433739 |
| TJP1 | tight junction protein 1 | -0.0431683 |
| POTEF | POTE ankyrin domain family, member F | -0.0422035 |
| MYO1E | myosin IE | -0.040835 |
| SP100 | SP100 nuclear antigen | -0.0406046 |
| EFNB2 | ephrin-B2 | -0.0400907 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0395746 |
| LYZ | lysozyme | -0.039568 |
| ABLIM1 | actin binding LIM protein 1 | -0.0395311 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0391104 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0390916 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0372164 |
| LMO7 | LIM domain 7 | -0.0363155 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0362223 |
| UBC | ubiquitin C | -0.0362093 |
| AREG | amphiregulin | -0.0360783 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0357763 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0356984 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0354988 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0354945 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0350894 |
| VMP1 | vacuole membrane protein 1 | -0.0348748 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0343117 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0343069 |
| TXNIP | thioredoxin interacting protein | -0.0341657 |
| RAB7A | RAB7A, member RAS oncogene family | -0.034013 |
| LCN2 | lipocalin 2 | -0.0334377 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.0333412 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.032345 |
| S100A10 | S100 calcium binding protein A10 | -0.032299 |
| PRKCA | protein kinase C, alpha | -0.0316844 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0311783 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0310689 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0305674 |
| RUNX1 | runt-related transcription factor 1 | -0.0305255 |
| INTS6 | integrator complex subunit 6 | -0.0301018 |
| BCLAF1 | BCL2-associated transcription factor 1 | -0.0300625 |
| TRIM2 | tripartite motif containing 2 | -0.0300169 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0297041 |
| HM13 | histocompatibility (minor) 13 | -0.0293901 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0292472 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0291449 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | -0.0282689 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0281523 |
| RIGI | RNA sensor RIG-I | -0.0281 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | -0.0280492 |
| SEC24A | SEC24 family member A | -0.0279631 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0277727 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0275127 |
| NT5C3A | 5'-nucleotidase, cytosolic IIIA | -0.0274854 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.027283 |
| PLSCR1 | phospholipid scramblase 1 | -0.0270009 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0266813 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0265384 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.026531 |
| RAB10 | RAB10, member RAS oncogene family | -0.0264736 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0261764 |
| MX2 | MX dynamin-like GTPase 2 | -0.0259426 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0258304 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0255483 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0251332 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | -0.0247367 |
| MAGT1 | magnesium transporter 1 | -0.0245992 |
| KLF6 | Kruppel-like factor 6 | -0.0245118 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0244137 |
| TFG | TRK-fused gene | -0.0241326 |
| ETV6 | ets variant 6 | -0.0236457 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0236324 |
| DSTN | destrin (actin depolymerizing factor) | -0.0236101 |
| MED13 | mediator complex subunit 13 | -0.023532 |
| LIPH | lipase, member H | -0.0229181 |
| SETD5 | SET domain containing 5 | -0.0225125 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0224894 |
| CCNI | cyclin I | -0.0224566 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0222255 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0221258 |