| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in HCT15 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_HCT15 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOC112694756 | uncharaterized LOC112694756 | 0.126752 |
| KRT8 | keratin 8, type II | 0.124239 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.117498 |
| KRT18 | keratin 18, type I | 0.0656122 |
| PLEC | plectin | 0.0631758 |
| RAD51B | RAD51 paralog B | 0.0620503 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0575228 |
| ZNF292 | zinc finger protein 292 | 0.0572903 |
| TXNRD1 | thioredoxin reductase 1 | 0.0550573 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0538507 |
| RPLP1 | ribosomal protein, large, P1 | 0.051284 |
| RPL35A | ribosomal protein L35a | 0.0500445 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0500252 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0497105 |
| RPL23 | ribosomal protein L23 | 0.0476559 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0473907 |
| YBX1 | Y box binding protein 1 | 0.0471759 |
| MLEC | malectin | 0.0470041 |
| RPL4 | ribosomal protein L4 | 0.045702 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0448136 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0431713 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0403297 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0400425 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0394644 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0393744 |
| PRELID2 | PRELI domain containing 2 | 0.0392292 |
| RPLP0 | ribosomal protein, large, P0 | 0.0382666 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0380752 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0377894 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0377151 |
| RPL37 | ribosomal protein L37 | 0.0376877 |
| GOLGA3 | golgin A3 | 0.037241 |
| RPL3 | ribosomal protein L3 | 0.0368804 |
| CALR | calreticulin | 0.0368477 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0362068 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.036114 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0361133 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0354539 |
| SEPTIN2 | septin 2 | 0.0351294 |
| RPL26 | ribosomal protein L26 | 0.0347564 |
| TMSB10 | thymosin beta 10 | 0.0346826 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0342981 |
| GANAB | glucosidase, alpha; neutral AB | 0.0340407 |
| HYOU1 | hypoxia up-regulated 1 | 0.0339914 |
| LASP1 | LIM and SH3 protein 1 | 0.0339278 |
| PCNT | pericentrin | 0.0337471 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0337196 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0333697 |
| FTL | ferritin, light polypeptide | 0.0333016 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0328595 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0322921 |
| TOMM20 | translocase of outer mitochondrial membrane 20 homolog (yeast) | 0.0322094 |
| PMM2 | phosphomannomutase 2 | 0.0318465 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0316926 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0316548 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0314965 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0310031 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0308738 |
| INSIG2 | insulin induced gene 2 | 0.0302968 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.0298184 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0297853 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0295836 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0295058 |
| SEMA3B | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B | 0.0294178 |
| NONO | non-POU domain containing, octamer-binding | 0.0289133 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0288529 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.028772 |
| RPS4X | ribosomal protein S4, X-linked | 0.0287252 |
| KAZN | kazrin, periplakin interacting protein | 0.0286255 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.02824 |
| FAM117B | family with sequence similarity 117, member B | 0.0276797 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0272744 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0272193 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0271885 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.0271259 |
| MORF4L1 | mortality factor 4 like 1 | 0.0269969 |
| KHNYN | KH and NYN domain containing | 0.0269905 |
| RPL8 | ribosomal protein L8 | 0.026737 |
| RPS9 | ribosomal protein S9 | 0.0264844 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0263781 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0263201 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0261773 |
| MED15 | mediator complex subunit 15 | 0.0261703 |
| WDR45B | WD repeat domain 45B | 0.0261515 |
| MINK1 | misshapen-like kinase 1 | 0.0259912 |
| PGK1 | phosphoglycerate kinase 1 | 0.025951 |
| APOL2 | apolipoprotein L, 2 | 0.0259452 |
| SF1 | splicing factor 1 | 0.0258779 |
| PLXNA3 | plexin A3 | 0.0258009 |
| ZNF516 | zinc finger protein 516 | 0.0256581 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.025398 |
| NFXL1 | nuclear transcription factor, X-box binding-like 1 | 0.0252503 |
| FUS | FUS RNA binding protein | 0.0250445 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0250358 |
| CTDSP2 | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2 | 0.0249246 |
| OBSCN | obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF | 0.0249178 |
| HDLBP | high density lipoprotein binding protein | 0.0247236 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0244125 |
| RPS19 | ribosomal protein S19 | 0.0243042 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0241882 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.250283 |
| AHNAK | AHNAK nucleoprotein | -0.111741 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0928345 |
| NDRG1 | N-myc downstream regulated 1 | -0.0827326 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0747772 |
| INTS6 | integrator complex subunit 6 | -0.0739446 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0729621 |
| PKM | pyruvate kinase, muscle | -0.0716058 |
| VCL | vinculin | -0.0676892 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0654201 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0642133 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0630505 |
| RPS2 | ribosomal protein S2 | -0.0621838 |
| MCL1 | myeloid cell leukemia 1 | -0.0585381 |
| POTEF | POTE ankyrin domain family, member F | -0.0532813 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0525975 |
| CLTC | clathrin, heavy chain (Hc) | -0.0512385 |
| ASPH | aspartate beta-hydroxylase | -0.0482925 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0474879 |
| SERINC5 | serine incorporator 5 | -0.0474511 |
| CDCP1 | CUB domain containing protein 1 | -0.0471881 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0468088 |
| TPM4 | tropomyosin 4 | -0.0456989 |
| VMP1 | vacuole membrane protein 1 | -0.045537 |
| PAPOLA | poly(A) polymerase alpha | -0.0450861 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0446898 |
| DSG2 | desmoglein 2 | -0.0446698 |
| SP100 | SP100 nuclear antigen | -0.0421225 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0418263 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0402738 |
| GOLGB1 | golgin B1 | -0.0398606 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.039817 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | -0.0389039 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0387102 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | -0.0386084 |
| MKI67 | marker of proliferation Ki-67 | -0.0376635 |
| JMJD1C | jumonji domain containing 1C | -0.0372225 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0371923 |
| EGR1 | early growth response 1 | -0.0368232 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0362052 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | -0.0354991 |
| AGO3 | argonaute RISC catalytic component 3 | -0.0351081 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0348999 |
| SNX14 | sorting nexin 14 | -0.0348027 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0343978 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.033989 |
| DSCAM | Down syndrome cell adhesion molecule | -0.0339442 |
| CRK | v-crk avian sarcoma virus CT10 oncogene homolog | -0.0338507 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.033742 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0335679 |
| LRRC23 | leucine rich repeat containing 23 | -0.032825 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0315196 |
| GLG1 | golgi glycoprotein 1 | -0.0313078 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0311282 |
| WASF2 | WAS protein family, member 2 | -0.0308853 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0307946 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0303285 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.030181 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0299674 |
| DSPP | dentin sialophosphoprotein | -0.0296908 |
| MYOF | myoferlin | -0.0293659 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0292994 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.029224 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0290925 |
| RAB10 | RAB10, member RAS oncogene family | -0.029078 |
| RCOR1 | REST corepressor 1 | -0.0288704 |
| MYO9A | myosin IXA | -0.0285598 |
| GPHN | gephyrin | -0.0284859 |
| TASOR2 | transcription activation suppressor family member 2 | -0.0282428 |
| PARD6B | par-6 family cell polarity regulator beta | -0.0281549 |
| CUX1 | cut-like homeobox 1 | -0.0281519 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0281481 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0281142 |
| ARRDC4 | arrestin domain containing 4 | -0.0280571 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0278887 |
| PLAUR | plasminogen activator, urokinase receptor | -0.0277815 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0277725 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0276083 |
| SRSF4 | serine/arginine-rich splicing factor 4 | -0.0275312 |
| TGFB1 | transforming growth factor, beta 1 | -0.0274542 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.027398 |
| DENND4C | DENN/MADD domain containing 4C | -0.0271974 |
| ERBIN | erbb2 interacting protein | -0.0267356 |
| UTRN | utrophin | -0.0267272 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0266941 |
| PERP | PERP, TP53 apoptosis effector | -0.0265425 |
| RTN3 | reticulon 3 | -0.0264692 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.026185 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | -0.0260083 |
| CENPF | centromere protein F, 350/400kDa | -0.0259315 |
| USP53 | ubiquitin specific peptidase 53 | -0.0258794 |
| NCKAP1 | NCK-associated protein 1 | -0.0258214 |
| ANXA3 | annexin A3 | -0.0255006 |
| KLF6 | Kruppel-like factor 6 | -0.0253588 |
| NKTR | natural killer cell triggering receptor | -0.0252724 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0251441 |
| RIC1 | RAB6A GEF complex partner 1 | -0.0250701 |
| DIAPH2 | diaphanous-related formin 2 | -0.025047 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0248658 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0248395 |
