| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in HEC-1-A cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_HEC-1-A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.184797 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.146581 |
| FLNA | filamin A, alpha | 0.124131 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.116307 |
| PLEC | plectin | 0.114892 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.101029 |
| NDRG1 | N-myc downstream regulated 1 | 0.0999608 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0943767 |
| TMSB10 | thymosin beta 10 | 0.0791335 |
| LAMB3 | laminin, beta 3 | 0.0702822 |
| PAX8 | paired box 8 | 0.0693043 |
| PGK1 | phosphoglycerate kinase 1 | 0.0678698 |
| APP | amyloid beta (A4) precursor protein | 0.0671047 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0647159 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0631808 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0611579 |
| TMSB4X | thymosin beta 4, X-linked | 0.06091 |
| MT2A | metallothionein 2A | 0.0584384 |
| FLNB | filamin B, beta | 0.0559107 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0557859 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0526874 |
| SMAD3 | SMAD family member 3 | 0.0519943 |
| KRT7 | keratin 7, type II | 0.0518428 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.049791 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0484428 |
| CALR | calreticulin | 0.0477862 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0463828 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0463108 |
| ANXA2 | annexin A2 | 0.045698 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0450115 |
| VEGFA | vascular endothelial growth factor A | 0.0446672 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0436388 |
| RPL3 | ribosomal protein L3 | 0.0417952 |
| RPL23 | ribosomal protein L23 | 0.0407883 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0405696 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.039955 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0395637 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0378394 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0377573 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0372522 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0372429 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.036754 |
| AHNAK | AHNAK nucleoprotein | 0.0365807 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0365797 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0365174 |
| HELZ | helicase with zinc finger | 0.0364804 |
| PTMA | prothymosin, alpha | 0.0358759 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0354966 |
| ACTN4 | actinin, alpha 4 | 0.0353465 |
| INSIG2 | insulin induced gene 2 | 0.0347176 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0332903 |
| YEATS2 | YEATS domain containing 2 | 0.0331251 |
| MINK1 | misshapen-like kinase 1 | 0.0327041 |
| CTBP2 | C-terminal binding protein 2 | 0.0326603 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0324014 |
| EPHA2 | EPH receptor A2 | 0.0322647 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0318534 |
| ENO1 | enolase 1, (alpha) | 0.0317962 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0314248 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0307278 |
| KRT18 | keratin 18, type I | 0.0306126 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0304692 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0297328 |
| RASA3 | RAS p21 protein activator 3 | 0.0293758 |
| MED15 | mediator complex subunit 15 | 0.0293391 |
| PLAU | plasminogen activator, urokinase | 0.0292641 |
| AMOTL2 | angiomotin like 2 | 0.0290962 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0288895 |
| RPL35A | ribosomal protein L35a | 0.0288834 |
| OGA | O-GlcNAcase | 0.028424 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0283733 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0282363 |
| YBX1 | Y box binding protein 1 | 0.0280867 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0277814 |
| ANKRD11 | ankyrin repeat domain 11 | 0.027603 |
| CEP250 | centrosomal protein 250kDa | 0.0266233 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.026067 |
| TPM3 | tropomyosin 3 | 0.0256352 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0256219 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0256046 |
| ANXA11 | annexin A11 | 0.0255677 |
| WDR45B | WD repeat domain 45B | 0.0255546 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0254899 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0254283 |
| NEK6 | NIMA-related kinase 6 | 0.0250112 |
| SEPTIN2 | septin 2 | 0.024975 |
| ACTG1 | actin gamma 1 | 0.0249276 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0244708 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0244235 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0243994 |
| PRELID2 | PRELI domain containing 2 | 0.0243731 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0243547 |
| IRS2 | insulin receptor substrate 2 | 0.0242816 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0242413 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0242049 |
| ACTN1 | actinin, alpha 1 | 0.0241792 |
| TNFAIP2 | tumor necrosis factor, alpha-induced protein 2 | 0.0240641 |
| PFKL | phosphofructokinase, liver | 0.0236917 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.0235392 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0233965 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.177665 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0986982 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0778268 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0760076 |
| CCND1 | cyclin D1 | -0.0726747 |
| TXNRD1 | thioredoxin reductase 1 | -0.0606401 |
| MAP4 | microtubule-associated protein 4 | -0.0603867 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0582572 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0556596 |
| RPS2 | ribosomal protein S2 | -0.0541212 |
| SVIL | supervillin | -0.0538627 |
| GOLGA4 | golgin A4 | -0.0506688 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0498453 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0492388 |
| NRIP1 | nuclear receptor interacting protein 1 | -0.0462802 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0462148 |
| CDK13 | cyclin-dependent kinase 13 | -0.045196 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0450981 |
| SSH2 | slingshot protein phosphatase 2 | -0.0437598 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0435948 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0435625 |
| JMJD1C | jumonji domain containing 1C | -0.0420627 |
| USP34 | ubiquitin specific peptidase 34 | -0.0419309 |
| BPTF | bromodomain PHD finger transcription factor | -0.041757 |
| ASPH | aspartate beta-hydroxylase | -0.0417435 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0412397 |
| VMP1 | vacuole membrane protein 1 | -0.0398564 |
| FNIP1 | folliculin interacting protein 1 | -0.0391615 |
| GOLGB1 | golgin B1 | -0.03896 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0381131 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | -0.0376274 |
| TCF12 | transcription factor 12 | -0.0369438 |
| DIAPH3 | diaphanous-related formin 3 | -0.0368647 |
| TUSC3 | tumor suppressor candidate 3 | -0.0367079 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.036446 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0359026 |
| CLTC | clathrin, heavy chain (Hc) | -0.0358022 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0356016 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0352071 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0346377 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.034637 |
| NF1 | neurofibromin 1 | -0.0335713 |
| TAOK1 | TAO kinase 1 | -0.0335444 |
| MACROD2 | MACRO domain containing 2 | -0.0335292 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.033397 |
| PAPOLA | poly(A) polymerase alpha | -0.0325668 |
| R3HDM1 | R3H domain containing 1 | -0.0323906 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0323379 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0322034 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0318717 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | -0.0316452 |
| FER | fer (fps/fes related) tyrosine kinase | -0.0315721 |
| FTL | ferritin, light polypeptide | -0.0314411 |
| HMGA2 | high mobility group AT-hook 2 | -0.0314255 |
| GPATCH8 | G patch domain containing 8 | -0.0313745 |
| RTN3 | reticulon 3 | -0.0310545 |
| CCDC138 | coiled-coil domain containing 138 | -0.0309397 |
| SETD2 | SET domain containing 2 | -0.0308811 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0304566 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0299073 |
| MKI67 | marker of proliferation Ki-67 | -0.0298782 |
| DSG2 | desmoglein 2 | -0.0296754 |
| ERBIN | erbb2 interacting protein | -0.0296552 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0296489 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.029596 |
| PKP4 | plakophilin 4 | -0.0295201 |
| GPHN | gephyrin | -0.0294676 |
| RANBP17 | RAN binding protein 17 | -0.0293479 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0293157 |
| NCKAP1 | NCK-associated protein 1 | -0.0291066 |
| PTK2 | protein tyrosine kinase 2 | -0.0290652 |
| SLMAP | sarcolemma associated protein | -0.0289049 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0288886 |
| BBX | bobby sox homolog (Drosophila) | -0.0287544 |
| SBF2 | SET binding factor 2 | -0.0284481 |
| POTEF | POTE ankyrin domain family, member F | -0.0281653 |
| RPL32 | ribosomal protein L32 | -0.0277672 |
| PLCB4 | phospholipase C, beta 4 | -0.0277185 |
| GNAQ | guanine nucleotide binding protein (G protein), q polypeptide | -0.0275448 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0274469 |
| MMS22L | MMS22-like, DNA repair protein | -0.0265094 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0260949 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0260108 |
| CD2AP | CD2-associated protein | -0.0259819 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0259652 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0257564 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0257142 |
| DSTN | destrin (actin depolymerizing factor) | -0.025597 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0255005 |
| ECT2 | epithelial cell transforming 2 | -0.0254724 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0252893 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0252331 |
| MED13 | mediator complex subunit 13 | -0.0250534 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0249047 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.024714 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0247104 |
| U2SURP | U2 snRNP-associated SURP domain containing | -0.0246662 |
| RHEX | regulator of hemoglobinization and erythroid cell expansion | -0.0245534 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0245446 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.02424 |
