| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in HOP62 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_HOP62 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.211327 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.095624 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0774858 |
| TMSB10 | thymosin beta 10 | 0.0680308 |
| MSN | moesin | 0.0619382 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0605681 |
| PTMA | prothymosin, alpha | 0.0567414 |
| RRM2 | ribonucleotide reductase M2 | 0.0480102 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.047384 |
| CLIC4 | chloride intracellular channel 4 | 0.0472692 |
| VCL | vinculin | 0.039111 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0375174 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0368791 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.036649 |
| CENPF | centromere protein F, 350/400kDa | 0.033745 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0327391 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.031765 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0312566 |
| VASP | vasodilator-stimulated phosphoprotein | 0.028901 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0287413 |
| SEPTIN9 | septin 9 | 0.028568 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0285061 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0279226 |
| TPI1 | triosephosphate isomerase 1 | 0.0273897 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0264768 |
| EGR1 | early growth response 1 | 0.0262634 |
| ACTR3 | ARP3 actin-related protein 3 homolog (yeast) | 0.0248135 |
| PCBP2 | poly(rC) binding protein 2 | 0.024209 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0236471 |
| NGLY1 | N-glycanase 1 | 0.0230223 |
| MEF2A | myocyte enhancer factor 2A | 0.0229085 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0225071 |
| RTN4 | reticulon 4 | 0.022384 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.022151 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0216501 |
| VMP1 | vacuole membrane protein 1 | 0.0214072 |
| SP3 | Sp3 transcription factor | 0.0209611 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0208024 |
| CAPRIN2 | caprin family member 2 | 0.0204503 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0203416 |
| CLEC1B | C-type lectin domain family 1, member B | 0.0202633 |
| STC1 | stanniocalcin 1 | 0.0199732 |
| TPX2 | TPX2, microtubule-associated | 0.0190728 |
| PRELID2 | PRELI domain containing 2 | 0.0187914 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0186197 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0184563 |
| AXL | AXL receptor tyrosine kinase | 0.0178091 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0177988 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0177479 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0176008 |
| S100A6 | S100 calcium binding protein A6 | 0.0175894 |
| SPRED1 | sprouty-related, EVH1 domain containing 1 | 0.0175587 |
| ATP13A3 | ATPase type 13A3 | 0.0175308 |
| TUBB6 | tubulin, beta 6 class V | 0.0168487 |
| FOSL1 | FOS-like antigen 1 | 0.0164222 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0163897 |
| NUP58 | nucleoporin 58 | 0.0163006 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | 0.0161081 |
| EIF5 | eukaryotic translation initiation factor 5 | 0.0159281 |
| NR1D2 | nuclear receptor subfamily 1, group D, member 2 | 0.0159112 |
| HPCAL1 | hippocalcin-like 1 | 0.0158635 |
| SET | SET nuclear proto-oncogene | 0.0157754 |
| USP3 | ubiquitin specific peptidase 3 | 0.0157637 |
| ITGAV | integrin, alpha V | 0.0156987 |
| RAI1 | retinoic acid induced 1 | 0.0154147 |
| ANLN | anillin, actin binding protein | 0.0151269 |
| ACTN1 | actinin, alpha 1 | 0.0150832 |
| IRS2 | insulin receptor substrate 2 | 0.0148768 |
| MCL1 | myeloid cell leukemia 1 | 0.0148341 |
| RPL3 | ribosomal protein L3 | 0.0146727 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0145446 |
| NONO | non-POU domain containing, octamer-binding | 0.0144126 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | 0.0142957 |
| CKAP2L | cytoskeleton associated protein 2-like | 0.0142862 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0141506 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.0141011 |
| CDCP1 | CUB domain containing protein 1 | 0.0139582 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0139532 |
| FLNB | filamin B, beta | 0.0139475 |
| TPM3 | tropomyosin 3 | 0.0138946 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0138294 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0136387 |
| TOP1 | topoisomerase (DNA) I | 0.0133918 |
| CD82 | CD82 molecule | 0.0131455 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0130743 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0130709 |
| DOT1L | DOT1-like histone H3K79 methyltransferase | 0.0126989 |
| KIF18B | kinesin family member 18B | 0.0126831 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0123295 |
| SPAG5 | sperm associated antigen 5 | 0.0122315 |
| MLEC | malectin | 0.0121581 |
| RNF220 | ring finger protein 220 | 0.0120768 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0120458 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.011927 |
| PFN1 | profilin 1 | 0.0116885 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0116822 |
| LUZP1 | leucine zipper protein 1 | 0.0115926 |
| PLS3 | plastin 3 | 0.0115771 |
| RCOR1 | REST corepressor 1 | 0.0115329 |
| SH2B3 | SH2B adaptor protein 3 | 0.011479 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.560564 |
| FN1 | fibronectin 1 | -0.28413 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.185934 |
| IGF2 | insulin-like growth factor 2 | -0.132008 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.121015 |
| HMGA2 | high mobility group AT-hook 2 | -0.120162 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.109971 |
| COL5A1 | collagen, type V, alpha 1 | -0.106885 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0930142 |
| NDRG1 | N-myc downstream regulated 1 | -0.0879192 |
| CD44 | CD44 molecule (Indian blood group) | -0.0733396 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0724086 |
| ANXA2 | annexin A2 | -0.0702757 |
| RPLP1 | ribosomal protein, large, P1 | -0.068037 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0656912 |
| CANX | calnexin | -0.0636921 |
| LOX | lysyl oxidase | -0.0633592 |
| CDH13 | cadherin 13 | -0.063154 |
| LAMB3 | laminin, beta 3 | -0.0604226 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0584999 |
| CCND1 | cyclin D1 | -0.0531558 |
| RAI14 | retinoic acid induced 14 | -0.0530609 |
| AHNAK | AHNAK nucleoprotein | -0.0529647 |
| RPS6 | ribosomal protein S6 | -0.0526149 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0503836 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0493261 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0484929 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0469496 |
| FTL | ferritin, light polypeptide | -0.0457111 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0450373 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0444114 |
| RPS8 | ribosomal protein S8 | -0.0439918 |
| ACTG1 | actin gamma 1 | -0.043539 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0419842 |
| HDLBP | high density lipoprotein binding protein | -0.041893 |
| CAVIN1 | caveolae associated protein 1 | -0.0402214 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0395429 |
| PTK2 | protein tyrosine kinase 2 | -0.0391001 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0370169 |
| GOLGB1 | golgin B1 | -0.0368986 |
| GOLGA4 | golgin A4 | -0.0362037 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0359899 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0358909 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0352287 |
| GLIS3 | GLIS family zinc finger 3 | -0.0348715 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.0342729 |
| RPL12 | ribosomal protein L12 | -0.0339862 |
| RPL35A | ribosomal protein L35a | -0.0336055 |
| RPL19 | ribosomal protein L19 | -0.0334909 |
| RPL8 | ribosomal protein L8 | -0.0334464 |
| RPL34 | ribosomal protein L34 | -0.0332478 |
| MMP12 | matrix metallopeptidase 12 | -0.0319031 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.0315338 |
| MORF4L2 | mortality factor 4 like 2 | -0.0314356 |
| EGFR | epidermal growth factor receptor | -0.0311592 |
| RPS24 | ribosomal protein S24 | -0.0311332 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0306898 |
| RPS13 | ribosomal protein S13 | -0.0301652 |
| GLG1 | golgi glycoprotein 1 | -0.0298945 |
| MTDH | metadherin | -0.0298204 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.029799 |
| IER3 | immediate early response 3 | -0.0297361 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0297047 |
| RUNX1 | runt-related transcription factor 1 | -0.0294949 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0293647 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0293476 |
| SQSTM1 | sequestosome 1 | -0.0292581 |
| SEC24D | SEC24 family member D | -0.0292111 |
| FMN1 | formin 1 | -0.0290121 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0286616 |
| JMJD1C | jumonji domain containing 1C | -0.0286465 |
| MAP4 | microtubule-associated protein 4 | -0.0285858 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0285706 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0284447 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0283773 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.0283571 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0282515 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0280084 |
| EMP1 | epithelial membrane protein 1 | -0.0277741 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.0276191 |
| DTNA | dystrobrevin, alpha | -0.0273422 |
| GNAS | GNAS complex locus | -0.027016 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0267873 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0265895 |
| VEGFA | vascular endothelial growth factor A | -0.0265256 |
| RPS27A | ribosomal protein S27a | -0.0262356 |
| NAV1 | neuron navigator 1 | -0.0260116 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0258665 |
| BPTF | bromodomain PHD finger transcription factor | -0.0257864 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0256067 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0254375 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0254312 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0254139 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0252836 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0249964 |
| FLNA | filamin A, alpha | -0.0249753 |
| NF1 | neurofibromin 1 | -0.0248442 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0246193 |
| HMGA1 | high mobility group AT-hook 1 | -0.0245495 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0243938 |
