| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Fumaric acid_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.411573 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.202609 |
| NDRG1 | N-myc downstream regulated 1 | 0.190737 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.175525 |
| VEGFA | vascular endothelial growth factor A | 0.167836 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.112243 |
| MT2A | metallothionein 2A | 0.111974 |
| PLEC | plectin | 0.0948354 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.0902443 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0868527 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0836673 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0736736 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0690513 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0529045 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.049895 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.046864 |
| NAV2 | neuron navigator 2 | 0.0454712 |
| FLNA | filamin A, alpha | 0.0430747 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0419909 |
| SMAD3 | SMAD family member 3 | 0.0405457 |
| COL5A1 | collagen, type V, alpha 1 | 0.040194 |
| APP | amyloid beta (A4) precursor protein | 0.0399382 |
| RPL3 | ribosomal protein L3 | 0.0388197 |
| CADM1 | cell adhesion molecule 1 | 0.0384473 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0352149 |
| MT1X | metallothionein 1X | 0.0349656 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0344581 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0340628 |
| MSN | moesin | 0.0336928 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0331375 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0325983 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.031735 |
| HLA-B | major histocompatibility complex, class I, B | 0.0311605 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.03104 |
| TNS1 | tensin 1 | 0.0310259 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0308982 |
| CABIN1 | calcineurin binding protein 1 | 0.0307102 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0294811 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0285965 |
| MYO9B | myosin IXB | 0.0271958 |
| RUNX1 | runt-related transcription factor 1 | 0.0268671 |
| FMNL2 | formin-like 2 | 0.0263732 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0249566 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0248389 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0247369 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0247263 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0245949 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0245064 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0244993 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0243421 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.024274 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0239802 |
| HYOU1 | hypoxia up-regulated 1 | 0.0239069 |
| ADM | adrenomedullin | 0.0230782 |
| MYO10 | myosin X | 0.0225775 |
| ARRDC3 | arrestin domain containing 3 | 0.0221617 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0220497 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0219782 |
| MED15 | mediator complex subunit 15 | 0.0218829 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.02183 |
| BRD2 | bromodomain containing 2 | 0.0217904 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0217245 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0216603 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0215323 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0214298 |
| FOSL1 | FOS-like antigen 1 | 0.0212429 |
| CALR | calreticulin | 0.0210898 |
| SEPTIN9 | septin 9 | 0.0207907 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0207856 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0196156 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0194831 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0192529 |
| TRAM2 | translocation associated membrane protein 2 | 0.0192163 |
| FLNB | filamin B, beta | 0.0191622 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0191617 |
| TMSB10 | thymosin beta 10 | 0.0190918 |
| HLA-C | major histocompatibility complex, class I, C | 0.0188139 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0184265 |
| YBX1 | Y box binding protein 1 | 0.0181986 |
| TMSB4X | thymosin beta 4, X-linked | 0.0181647 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.018058 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.018009 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0179574 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0178485 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0178219 |
| MTSS1 | metastasis suppressor 1 | 0.0176603 |
| CTBP2 | C-terminal binding protein 2 | 0.0174859 |
| APOL2 | apolipoprotein L, 2 | 0.0174233 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0173522 |
| YEATS2 | YEATS domain containing 2 | 0.0173415 |
| SETD5 | SET domain containing 5 | 0.0172913 |
| CCNY | cyclin Y | 0.0172896 |
| CMIP | c-Maf inducing protein | 0.0172785 |
| SDC4 | syndecan 4 | 0.0172185 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0167526 |
| FAM219A | family with sequence similarity 219, member A | 0.0167381 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0166803 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0166463 |
| AXL | AXL receptor tyrosine kinase | 0.0166026 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0165639 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | -0.228019 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.209764 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.20459 |
| COL1A1 | collagen, type I, alpha 1 | -0.141667 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.119356 |
| VIM | vimentin | -0.0971639 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0782294 |
| LOX | lysyl oxidase | -0.0661293 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0593799 |
| CD44 | CD44 molecule (Indian blood group) | -0.0562188 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0530365 |
| IER3 | immediate early response 3 | -0.0526806 |
| COL1A2 | collagen, type I, alpha 2 | -0.0515504 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0474798 |
| HMGA2 | high mobility group AT-hook 2 | -0.0417208 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0391517 |
| FBN1 | fibrillin 1 | -0.038403 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0374101 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0370929 |
| CANX | calnexin | -0.036985 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0362009 |
| COL3A1 | collagen, type III, alpha 1 | -0.0360369 |
| POSTN | periostin, osteoblast specific factor | -0.0353019 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0350794 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0349806 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0333555 |
| CDH13 | cadherin 13 | -0.0333298 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0330806 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.032665 |
| OSMR | oncostatin M receptor | -0.0321293 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0320923 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0313472 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0312459 |
| ENO1 | enolase 1, (alpha) | -0.0297548 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0289866 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0287449 |
| GLIS3 | GLIS family zinc finger 3 | -0.0282378 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0272769 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.027136 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0269443 |
| MAP4 | microtubule-associated protein 4 | -0.0265445 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0261 |
| PALLD | palladin, cytoskeletal associated protein | -0.0260917 |
| CNTN5 | contactin 5 | -0.0258237 |
| ASPH | aspartate beta-hydroxylase | -0.0244678 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0244047 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0239777 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0239756 |
| DSTN | destrin (actin depolymerizing factor) | -0.0233111 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0229964 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0225994 |
| ANXA2 | annexin A2 | -0.0225712 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0225455 |
| MTDH | metadherin | -0.0218664 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0212091 |
| SP100 | SP100 nuclear antigen | -0.0209901 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0209682 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0209181 |
| GOLGA4 | golgin A4 | -0.0204982 |
| CALD1 | caldesmon 1 | -0.019944 |
| HMGA1 | high mobility group AT-hook 1 | -0.019922 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0195528 |
| THY1 | Thy-1 cell surface antigen | -0.0194009 |
| GNAS | GNAS complex locus | -0.0193649 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0190282 |
| RPS8 | ribosomal protein S8 | -0.0190105 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0189072 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0188713 |
| STC1 | stanniocalcin 1 | -0.0188317 |
| SRGN | serglycin | -0.0188059 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.018582 |
| VCL | vinculin | -0.0185778 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0185397 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0185231 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.018468 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0183334 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0182205 |
| TMEM263 | transmembrane protein 263 | -0.0179667 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0178488 |
| BBS9 | Bardet-Biedl syndrome 9 | -0.0177736 |
| TRAM1 | translocation associated membrane protein 1 | -0.0177623 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0172681 |
| NRP1 | neuropilin 1 | -0.017261 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0172256 |
| MAP1B | microtubule-associated protein 1B | -0.0172049 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.017148 |
| PLSCR1 | phospholipid scramblase 1 | -0.0170219 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0168971 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0167687 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0166422 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0166254 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0165858 |
| ATM | ATM serine/threonine kinase | -0.0164688 |
| RPL8 | ribosomal protein L8 | -0.0162627 |
| RPLP0 | ribosomal protein, large, P0 | -0.0161417 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0161392 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0160915 |
| RPS2 | ribosomal protein S2 | -0.0159473 |
| IL6ST | interleukin 6 signal transducer | -0.0159384 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0156944 |
