| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in HT-29 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_HT-29 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NDRG1 | N-myc downstream regulated 1 | 0.162181 |
| KRT8 | keratin 8, type II | 0.144155 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.132059 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0976557 |
| KRT18 | keratin 18, type I | 0.0935428 |
| VEGFA | vascular endothelial growth factor A | 0.0840441 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0716262 |
| PLEC | plectin | 0.071169 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0674368 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0607124 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.058735 |
| PGK1 | phosphoglycerate kinase 1 | 0.0551845 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0510504 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0475887 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0463166 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0438131 |
| RPL3 | ribosomal protein L3 | 0.0424669 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0420825 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.042007 |
| RPL23 | ribosomal protein L23 | 0.042005 |
| PTPRF | protein tyrosine phosphatase, receptor type, F | 0.0419102 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0412558 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0404705 |
| HYOU1 | hypoxia up-regulated 1 | 0.0402452 |
| MYO18A | myosin XVIIIA | 0.0383552 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0373603 |
| ANXA11 | annexin A11 | 0.0359667 |
| EPS8L1 | EPS8-like 1 | 0.035881 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0354246 |
| FAM13A | family with sequence similarity 13, member A | 0.0348551 |
| NIBAN2 | niban apoptosis regulator 2 | 0.034789 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0345232 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0335637 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0331874 |
| DNM2 | dynamin 2 | 0.0324406 |
| TNS1 | tensin 1 | 0.0317864 |
| CALR | calreticulin | 0.031116 |
| LMNA | lamin A/C | 0.0308717 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0301678 |
| MED15 | mediator complex subunit 15 | 0.0298949 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0293386 |
| RPL13A | ribosomal protein L13a | 0.0289856 |
| NONO | non-POU domain containing, octamer-binding | 0.0286088 |
| FLNA | filamin A, alpha | 0.0284919 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0278422 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.0278176 |
| ITGB4 | integrin, beta 4 | 0.0275511 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0269364 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0269237 |
| TMSB10 | thymosin beta 10 | 0.0264992 |
| ST14 | suppression of tumorigenicity 14 (colon carcinoma) | 0.0262671 |
| ACTN4 | actinin, alpha 4 | 0.0261106 |
| LAMB3 | laminin, beta 3 | 0.0256361 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0256118 |
| JUP | junction plakoglobin | 0.0255815 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0255476 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0253058 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0252296 |
| MLPH | melanophilin | 0.0252261 |
| SET | SET nuclear proto-oncogene | 0.0248549 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0243665 |
| RPL4 | ribosomal protein L4 | 0.0243107 |
| EPHA2 | EPH receptor A2 | 0.0241133 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0237091 |
| MAL2 | mal, T-cell differentiation protein 2 (gene/pseudogene) | 0.0234542 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0233731 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0233067 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0230985 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0227551 |
| OGA | O-GlcNAcase | 0.0224688 |
| AGRN | agrin | 0.0224524 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0223159 |
| CCNY | cyclin Y | 0.0223075 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0218356 |
| LAMA5 | laminin, alpha 5 | 0.0217319 |
| BCL3 | B-cell CLL/lymphoma 3 | 0.0216934 |
| VASP | vasodilator-stimulated phosphoprotein | 0.021686 |
| PTMA | prothymosin, alpha | 0.021674 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0213781 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0211784 |
| TPM3 | tropomyosin 3 | 0.0211514 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0211055 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0210983 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0208722 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0207068 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0204066 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0203764 |
| C1D | C1D nuclear receptor corepressor | 0.0203665 |
| ARAP1 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | 0.0203658 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0203019 |
| GRAMD1B | GRAM domain containing 1B | 0.0202018 |
| MINK1 | misshapen-like kinase 1 | 0.0200938 |
| KRT17 | keratin 17, type I | 0.0200825 |
| APP | amyloid beta (A4) precursor protein | 0.0200485 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.0199143 |
| EEIG1 | estrogen-induced osteoclastogenesis regulator 1 | 0.0198324 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0198202 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0197216 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.019695 |
| PTPRH | protein tyrosine phosphatase, receptor type, H | 0.0196596 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.194697 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110149 |
| EXT1 | exostosin glycosyltransferase 1 | -0.098621 |
| TJP1 | tight junction protein 1 | -0.0883387 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0807361 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0774133 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0771669 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0771044 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.07496 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0717861 |
| KRT20 | keratin 20, type I | -0.0712523 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0702822 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0684765 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0675755 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0675298 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0674364 |
| FTL | ferritin, light polypeptide | -0.0631827 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0617395 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.061708 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0602096 |
| INTS6 | integrator complex subunit 6 | -0.0596583 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0589938 |
| LYZ | lysozyme | -0.0559652 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0535686 |
| RTN3 | reticulon 3 | -0.0529366 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0528692 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0528636 |
| MYO1E | myosin IE | -0.0525168 |
| CD2AP | CD2-associated protein | -0.0523411 |
| TMEM123 | transmembrane protein 123 | -0.0513145 |
| RPS6 | ribosomal protein S6 | -0.0508518 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0503977 |
| POF1B | premature ovarian failure, 1B | -0.0503182 |
| LMO7 | LIM domain 7 | -0.0503151 |
| NF1 | neurofibromin 1 | -0.0497829 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0488983 |
| TXNRD1 | thioredoxin reductase 1 | -0.0483787 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0480716 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0452826 |
| NSMCE2 | non-SMC element 2, MMS21 homolog (S. cerevisiae) | -0.0447419 |
| AGR2 | anterior gradient 2 | -0.0446941 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0446023 |
| CANX | calnexin | -0.0438732 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | -0.0438045 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0422523 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0418517 |
| FRY | furry homolog (Drosophila) | -0.0416126 |
| JMJD1C | jumonji domain containing 1C | -0.0414182 |
| EXPH5 | exophilin 5 | -0.0411582 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0406889 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0404603 |
| RPS24 | ribosomal protein S24 | -0.0399006 |
| GOLGB1 | golgin B1 | -0.0397304 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0391653 |
| BPTF | bromodomain PHD finger transcription factor | -0.0380489 |
| MLLT3 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | -0.0371888 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0370708 |
| RPS2 | ribosomal protein S2 | -0.0370253 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0370238 |
| RPS5 | ribosomal protein S5 | -0.0369607 |
| MAGT1 | magnesium transporter 1 | -0.0369543 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.035948 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0355128 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0350606 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0349671 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0345473 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0345471 |
| GCNT3 | glucosaminyl (N-acetyl) transferase 3, mucin type | -0.0344543 |
| VCL | vinculin | -0.0341925 |
| VMP1 | vacuole membrane protein 1 | -0.0341341 |
| CDK13 | cyclin-dependent kinase 13 | -0.0334612 |
| EPB41L5 | erythrocyte membrane protein band 4.1 like 5 | -0.0334365 |
| TMEM65 | transmembrane protein 65 | -0.0332402 |
| ATXN1 | ataxin 1 | -0.0326362 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0325061 |
| TCF12 | transcription factor 12 | -0.032395 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0321902 |
| RAB10 | RAB10, member RAS oncogene family | -0.0319225 |
| UBC | ubiquitin C | -0.0317869 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0309938 |
| DGKH | diacylglycerol kinase, eta | -0.0302209 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0299129 |
| PDZD8 | PDZ domain containing 8 | -0.0296781 |
| CCNI | cyclin I | -0.0295576 |
| EXOC4 | exocyst complex component 4 | -0.029514 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0294576 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0294142 |
| LARP1B | La ribonucleoprotein domain family, member 1B | -0.0294119 |
| NBEAL1 | neurobeachin-like 1 | -0.0292794 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0291617 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0288847 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0288593 |
| COG5 | component of oligomeric golgi complex 5 | -0.0288341 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.028196 |
| CLTC | clathrin, heavy chain (Hc) | -0.0280084 |
| PTK2 | protein tyrosine kinase 2 | -0.0278052 |
| RPS23 | ribosomal protein S23 | -0.0270985 |
| LAMA4 | laminin, alpha 4 | -0.0269309 |
| ZNF207 | zinc finger protein 207 | -0.0268699 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0267893 |
