| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in J82 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_J82 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.202647 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.175022 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.1575 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.151458 |
| HLA-C | major histocompatibility complex, class I, C | 0.106537 |
| NDRG1 | N-myc downstream regulated 1 | 0.0890331 |
| HLA-B | major histocompatibility complex, class I, B | 0.0832973 |
| NAV2 | neuron navigator 2 | 0.0808931 |
| PODXL | podocalyxin-like | 0.0778017 |
| VEGFA | vascular endothelial growth factor A | 0.0571979 |
| MSN | moesin | 0.0537748 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0536669 |
| ADM | adrenomedullin | 0.0530362 |
| FLNB | filamin B, beta | 0.0518 |
| PLEC | plectin | 0.0511392 |
| FOSL1 | FOS-like antigen 1 | 0.0506853 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0496499 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0486842 |
| NONO | non-POU domain containing, octamer-binding | 0.0474158 |
| FLNA | filamin A, alpha | 0.0470501 |
| LOC112694756 | uncharaterized LOC112694756 | 0.044232 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0433054 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | 0.0427636 |
| ZNF841 | zinc finger protein 841 | 0.0411029 |
| KRT8 | keratin 8, type II | 0.0405619 |
| CEP250 | centrosomal protein 250kDa | 0.040168 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0401606 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0392221 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0382605 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0375555 |
| COL5A1 | collagen, type V, alpha 1 | 0.0375498 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0353707 |
| TMSB4X | thymosin beta 4, X-linked | 0.035201 |
| SMAD3 | SMAD family member 3 | 0.0342762 |
| ACTN1 | actinin, alpha 1 | 0.0340805 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.033151 |
| RPL3 | ribosomal protein L3 | 0.0327146 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0320912 |
| FRMD6 | FERM domain containing 6 | 0.0308537 |
| RLIM | ring finger protein, LIM domain interacting | 0.0308397 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0304938 |
| HLA-A | major histocompatibility complex, class I, A | 0.030417 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0302898 |
| CPNE1 | copine I | 0.0302155 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0296715 |
| RPL35A | ribosomal protein L35a | 0.0289015 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0277648 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0276344 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0265966 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0263565 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | 0.025527 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0247997 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0244572 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.0242431 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0241619 |
| DTNA | dystrobrevin, alpha | 0.0241097 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0240089 |
| SEPTIN9 | septin 9 | 0.0239485 |
| MT2A | metallothionein 2A | 0.0238973 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0235517 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0231414 |
| CADM1 | cell adhesion molecule 1 | 0.0229047 |
| NAV1 | neuron navigator 1 | 0.0227759 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0227081 |
| YBX1 | Y box binding protein 1 | 0.0224339 |
| DIDO1 | death inducer-obliterator 1 | 0.0221928 |
| ACTG1 | actin gamma 1 | 0.0221184 |
| CNOT12 | CCR4-NOT transcription complex subunit 12 | 0.0217428 |
| JUN | jun proto-oncogene | 0.0216213 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0211258 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0210669 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0209912 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0209858 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.0200692 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0199159 |
| MINK1 | misshapen-like kinase 1 | 0.0197758 |
| EFHD2 | EF-hand domain family, member D2 | 0.0195031 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0194262 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0191986 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0191154 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0191091 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0191072 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.0190762 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0189463 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0188808 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | 0.01881 |
| PFKP | phosphofructokinase, platelet | 0.018717 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0185008 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0183009 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0182264 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0181908 |
| DDX41 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 41 | 0.0181132 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0180249 |
| IQGAP3 | IQ motif containing GTPase activating protein 3 | 0.0179492 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0178403 |
| GOLGA3 | golgin A3 | 0.0177712 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | 0.0177247 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.017702 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0176336 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0175666 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.251794 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.170741 |
| DEK | DEK proto-oncogene | -0.110425 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0884437 |
| FTL | ferritin, light polypeptide | -0.0760883 |
| FN1 | fibronectin 1 | -0.0758048 |
| TXNRD1 | thioredoxin reductase 1 | -0.0742516 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0665554 |
| GLIS3 | GLIS family zinc finger 3 | -0.0619946 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0537234 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0536412 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0533977 |
| ENO1 | enolase 1, (alpha) | -0.0527247 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0516545 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0510177 |
| CANX | calnexin | -0.0503195 |
| AHNAK | AHNAK nucleoprotein | -0.0460985 |
| GOLGA4 | golgin A4 | -0.0456827 |
| DIAPH3 | diaphanous-related formin 3 | -0.0450448 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0443802 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0443372 |
| MAP4 | microtubule-associated protein 4 | -0.042742 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | -0.0420779 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0416149 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0404204 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0387336 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0378059 |
| CD44 | CD44 molecule (Indian blood group) | -0.0369842 |
| GNAS | GNAS complex locus | -0.036211 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0360655 |
| UBC | ubiquitin C | -0.0358832 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0357276 |
| MAP1B | microtubule-associated protein 1B | -0.0351559 |
| LOX | lysyl oxidase | -0.0348541 |
| POSTN | periostin, osteoblast specific factor | -0.0347806 |
| MTDH | metadherin | -0.0343465 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0341704 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0341112 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0339997 |
| PTMA | prothymosin, alpha | -0.0338593 |
| RAI14 | retinoic acid induced 14 | -0.033324 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0328294 |
| ZFR | zinc finger RNA binding protein | -0.0326167 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.03256 |
| IPO7 | importin 7 | -0.0322529 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0321393 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0320285 |
| HMGB1 | high mobility group box 1 | -0.0317955 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0317928 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0310268 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0309956 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.0308696 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0307465 |
| GOLGB1 | golgin B1 | -0.0306907 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0306728 |
| CCND1 | cyclin D1 | -0.0305485 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.030395 |
| ZNF804A | zinc finger protein 804A | -0.0303389 |
| NF1 | neurofibromin 1 | -0.0302417 |
| UFM1 | ubiquitin-fold modifier 1 | -0.0292366 |
| PPME1 | protein phosphatase methylesterase 1 | -0.0288754 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.028691 |
| PLCB4 | phospholipase C, beta 4 | -0.0282234 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.028035 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0275879 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0275149 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0272871 |
| ERBIN | erbb2 interacting protein | -0.0271547 |
| HMGB2 | high mobility group box 2 | -0.0271378 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0268774 |
| CALR | calreticulin | -0.026693 |
| ANXA2 | annexin A2 | -0.0264887 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0263129 |
| RBM25 | RNA binding motif protein 25 | -0.026227 |
| COL3A1 | collagen, type III, alpha 1 | -0.0262222 |
| S100A10 | S100 calcium binding protein A10 | -0.0261658 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0259693 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | -0.0257842 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.02575 |
| VEGFC | vascular endothelial growth factor C | -0.025658 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | -0.025484 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0254485 |
| TMEM263 | transmembrane protein 263 | -0.0253931 |
| OSMR | oncostatin M receptor | -0.0253717 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0252911 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.025262 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0250467 |
| NOP58 | NOP58 ribonucleoprotein | -0.0249178 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.024781 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0245636 |
| PTX3 | pentraxin 3, long | -0.0245635 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0244385 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | -0.0243265 |
| IER3 | immediate early response 3 | -0.0243215 |
| HLA-E | major histocompatibility complex, class I, E | -0.0242576 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0242279 |
| SEPTIN7 | septin 7 | -0.0241871 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0240964 |
| RTN3 | reticulon 3 | -0.0240484 |
| RPL12 | ribosomal protein L12 | -0.0238293 |
