| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FGFR2 | fibroblast growth factor receptor 2 | 0.162543 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.12973 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.126507 |
| KRT8 | keratin 8, type II | 0.114557 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.105785 |
| PLEC | plectin | 0.0848018 |
| KRT18 | keratin 18, type I | 0.0840949 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0833186 |
| VEGFA | vascular endothelial growth factor A | 0.0766443 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.070352 |
| ITGB4 | integrin, beta 4 | 0.0628302 |
| HYOU1 | hypoxia up-regulated 1 | 0.0606913 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0603926 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0601252 |
| TMSB10 | thymosin beta 10 | 0.0597968 |
| FLNB | filamin B, beta | 0.0589666 |
| TMSB4X | thymosin beta 4, X-linked | 0.057543 |
| LOC112694756 | uncharaterized LOC112694756 | 0.05673 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0529734 |
| ANLN | anillin, actin binding protein | 0.0522331 |
| ANXA11 | annexin A11 | 0.0521524 |
| NONO | non-POU domain containing, octamer-binding | 0.0486016 |
| BCL2L1 | BCL2-like 1 | 0.0470091 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0464874 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0456599 |
| B2M | beta-2-microglobulin | 0.0455655 |
| EZR | ezrin | 0.045372 |
| HLA-B | major histocompatibility complex, class I, B | 0.0444981 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0420339 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0413842 |
| NDRG1 | N-myc downstream regulated 1 | 0.0411248 |
| HLA-A | major histocompatibility complex, class I, A | 0.0410413 |
| FAM13A | family with sequence similarity 13, member A | 0.0404182 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0379541 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0378416 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0377491 |
| ITGA6 | integrin, alpha 6 | 0.0368144 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0364022 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0363597 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0359735 |
| MINK1 | misshapen-like kinase 1 | 0.0341357 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0339279 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0338929 |
| FAT1 | FAT atypical cadherin 1 | 0.0338726 |
| SET | SET nuclear proto-oncogene | 0.0338539 |
| CCNY | cyclin Y | 0.0336762 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0334422 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0329406 |
| ACTN4 | actinin, alpha 4 | 0.0328909 |
| RPL3 | ribosomal protein L3 | 0.0321271 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0319612 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0317615 |
| OGA | O-GlcNAcase | 0.0316082 |
| PCBP2 | poly(rC) binding protein 2 | 0.031473 |
| CD9 | CD9 molecule | 0.0312292 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.030968 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0308477 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0308103 |
| YEATS2 | YEATS domain containing 2 | 0.0293543 |
| AFDN | afadin, adherens junction formation factor | 0.0292518 |
| C6ORF132 | chromosome 6 open reading frame 132 | 0.0286337 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.028422 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0280792 |
| BCL9L | B-cell CLL/lymphoma 9-like | 0.0278193 |
| DNM2 | dynamin 2 | 0.0276169 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0274861 |
| RNASE12 | ribonuclease, RNase A family, 12 (non-active) | 0.027462 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.0270998 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0269449 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0268375 |
| EPHA2 | EPH receptor A2 | 0.0267789 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.026294 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0262048 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0258553 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.025651 |
| SPINT2 | serine peptidase inhibitor, Kunitz type, 2 | 0.0253333 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0253278 |
| SUPT6H | suppressor of Ty 6 homolog (S. cerevisiae) | 0.0251256 |
| RAI1 | retinoic acid induced 1 | 0.025098 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0250967 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0246811 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0246761 |
| TPM3 | tropomyosin 3 | 0.0243017 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0242226 |
| TBCD | tubulin folding cofactor D | 0.0240159 |
| CALR | calreticulin | 0.0235989 |
| JUP | junction plakoglobin | 0.0234248 |
| WWC1 | WW and C2 domain containing 1 | 0.0232637 |
| CPNE1 | copine I | 0.0231803 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0231016 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.022968 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0228572 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0228258 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0227551 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0226038 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0225043 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0223953 |
| PKM | pyruvate kinase, muscle | 0.0222181 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0220729 |
| KRT19 | keratin 19, type I | 0.0220518 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.287489 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.172388 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.104892 |
| LMO7 | LIM domain 7 | -0.102419 |
| AGR2 | anterior gradient 2 | -0.0953417 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.077123 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.073202 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.062354 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0566106 |
| TMEM123 | transmembrane protein 123 | -0.0538225 |
| CANX | calnexin | -0.0485391 |
| CDK13 | cyclin-dependent kinase 13 | -0.0480017 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0471796 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0470629 |
| TMC5 | transmembrane channel-like 5 | -0.0457309 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0454315 |
| GOLGB1 | golgin B1 | -0.0453514 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0452955 |
| EHBP1 | EH domain binding protein 1 | -0.0443784 |
| POF1B | premature ovarian failure, 1B | -0.0437093 |
| ATF7IP2 | activating transcription factor 7 interacting protein 2 | -0.0427086 |
| ANXA2 | annexin A2 | -0.0425634 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0399597 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0393201 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.038754 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0385403 |
| RPS25 | ribosomal protein S25 | -0.0375182 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0368812 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0368067 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0338471 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0330933 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0329389 |
| RTN3 | reticulon 3 | -0.0326644 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0324201 |
| AHR | aryl hydrocarbon receptor | -0.0323086 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | -0.0322693 |
| MCU | mitochondrial calcium uniporter | -0.032161 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0304993 |
| FTL | ferritin, light polypeptide | -0.030489 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0302719 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0299879 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0299719 |
| CD2AP | CD2-associated protein | -0.0299446 |
| CDK6 | cyclin-dependent kinase 6 | -0.0298943 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0297922 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0297815 |
| PLSCR1 | phospholipid scramblase 1 | -0.0297595 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0296806 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0296401 |
| SP100 | SP100 nuclear antigen | -0.0295777 |
| KLF5 | Kruppel-like factor 5 (intestinal) | -0.0295558 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.029219 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0291006 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0290616 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0284909 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.028358 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0282417 |
| DSTN | destrin (actin depolymerizing factor) | -0.0281411 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0279007 |
| GPHN | gephyrin | -0.0278695 |
| RPL34 | ribosomal protein L34 | -0.0278634 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0278394 |
| PCSK5 | proprotein convertase subtilisin/kexin type 5 | -0.027541 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0271348 |
| RPS24 | ribosomal protein S24 | -0.0268889 |
| GOLGA4 | golgin A4 | -0.0263532 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0259895 |
| ATM | ATM serine/threonine kinase | -0.0255517 |
| IER3 | immediate early response 3 | -0.0252079 |
| EMP1 | epithelial membrane protein 1 | -0.0250492 |
| XAF1 | XIAP associated factor 1 | -0.0248385 |
| RPS8 | ribosomal protein S8 | -0.0247984 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0246916 |
| RAB2A | RAB2A, member RAS oncogene family | -0.0245263 |
| FRMD5 | FERM domain containing 5 | -0.0245258 |
| PPIB | peptidylprolyl isomerase B (cyclophilin B) | -0.0242943 |
| INTS6 | integrator complex subunit 6 | -0.024071 |
| EXT1 | exostosin glycosyltransferase 1 | -0.023975 |
| GPX2 | glutathione peroxidase 2 | -0.0239671 |
| BPTF | bromodomain PHD finger transcription factor | -0.0239056 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.023732 |
| RPS6 | ribosomal protein S6 | -0.0236489 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0235049 |
| HM13 | histocompatibility (minor) 13 | -0.0234526 |
| TRAM1 | translocation associated membrane protein 1 | -0.0232575 |
| DEK | DEK proto-oncogene | -0.0231979 |
| SSR1 | signal sequence receptor, alpha | -0.0231059 |
| HMGA1 | high mobility group AT-hook 1 | -0.0229582 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0229307 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0228829 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0228095 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0226352 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0226334 |
| MUC17 | mucin 17, cell surface associated | -0.0225547 |
| MTDH | metadherin | -0.0224929 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0224436 |
| HMGB1 | high mobility group box 1 | -0.0224301 |
| TXNRD1 | thioredoxin reductase 1 | -0.0222491 |
| SQSTM1 | sequestosome 1 | -0.0221256 |
| NPSR1 | neuropeptide S receptor 1 | -0.0220487 |
