| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in LOX-IMVI cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_LOX-IMVI drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.172822 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.156615 |
| LOC112694756 | uncharaterized LOC112694756 | 0.121111 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.101372 |
| PGK1 | phosphoglycerate kinase 1 | 0.100932 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0878305 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0841969 |
| TMSB10 | thymosin beta 10 | 0.0792478 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0688364 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0665084 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0662468 |
| PLEC | plectin | 0.0635412 |
| YBX3 | Y box binding protein 3 | 0.058877 |
| ANXA2 | annexin A2 | 0.0577542 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0574049 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0568598 |
| FLNA | filamin A, alpha | 0.0565473 |
| RPL3 | ribosomal protein L3 | 0.0528898 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.051912 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.050713 |
| WDR45B | WD repeat domain 45B | 0.0505093 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0500841 |
| APP | amyloid beta (A4) precursor protein | 0.0495835 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0492409 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0483071 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.048122 |
| NONO | non-POU domain containing, octamer-binding | 0.0472353 |
| DTNA | dystrobrevin, alpha | 0.0468689 |
| RPL23 | ribosomal protein L23 | 0.0437754 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0431837 |
| RPL4 | ribosomal protein L4 | 0.0429385 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0426763 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0422109 |
| RUNX1 | runt-related transcription factor 1 | 0.0416601 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0409072 |
| CORO1C | coronin, actin binding protein, 1C | 0.0408754 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0392334 |
| EIF3E | eukaryotic translation initiation factor 3, subunit E | 0.0386939 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0386104 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0383667 |
| NUP58 | nucleoporin 58 | 0.0383462 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0380134 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0367274 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0365409 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0362333 |
| JUN | jun proto-oncogene | 0.0356873 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0353825 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0353789 |
| YBX1 | Y box binding protein 1 | 0.0353122 |
| USP3 | ubiquitin specific peptidase 3 | 0.0353058 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0352191 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0351415 |
| LDHA | lactate dehydrogenase A | 0.0348474 |
| CD109 | CD109 molecule | 0.0347032 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0338149 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0336379 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0322964 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | 0.0322456 |
| RPL11 | ribosomal protein L11 | 0.03186 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0316772 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0310897 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0310352 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0305659 |
| MIDEAS | mitotic deacetylase associated SANT domain protein | 0.0305547 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0296039 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0295628 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.02925 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.029238 |
| ATP13A3 | ATPase type 13A3 | 0.0286458 |
| WDR43 | WD repeat domain 43 | 0.0281597 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0278738 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0278177 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0277851 |
| FLNC | filamin C, gamma | 0.0276928 |
| ARID1A | AT rich interactive domain 1A (SWI-like) | 0.0276826 |
| MMP12 | matrix metallopeptidase 12 | 0.0275402 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0273311 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0272782 |
| RPS4X | ribosomal protein S4, X-linked | 0.0270118 |
| RNF145 | ring finger protein 145 | 0.0269974 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0269843 |
| RTTN | rotatin | 0.0269319 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0269237 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0269236 |
| DST | dystonin | 0.0267613 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0265805 |
| ACTN1 | actinin, alpha 1 | 0.0265738 |
| RPL37 | ribosomal protein L37 | 0.0265613 |
| ATF3 | activating transcription factor 3 | 0.025874 |
| RLF | rearranged L-myc fusion | 0.0258613 |
| PUM1 | pumilio RNA-binding family member 1 | 0.025837 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0255541 |
| FRMD6 | FERM domain containing 6 | 0.0254113 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0252211 |
| RPL41 | ribosomal protein L41 | 0.0251487 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0249519 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0248895 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0245131 |
| VGF | VGF nerve growth factor inducible | 0.0244512 |
| NDRG1 | N-myc downstream regulated 1 | 0.0244465 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.366163 |
| PRKG1 | protein kinase, cGMP-dependent, type I | -0.10804 |
| FTL | ferritin, light polypeptide | -0.107659 |
| GPC6 | glypican 6 | -0.0995464 |
| EFNA5 | ephrin-A5 | -0.0754567 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0683726 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0661798 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0611164 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0602804 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0594028 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0567714 |
| RIGI | RNA sensor RIG-I | -0.0555967 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0547009 |
| ASPH | aspartate beta-hydroxylase | -0.0494254 |
| RPS2 | ribosomal protein S2 | -0.0454271 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0444677 |
| TMPRSS15 | transmembrane protease, serine 15 | -0.0440488 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0435027 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0421636 |
| USP34 | ubiquitin specific peptidase 34 | -0.0414998 |
| INTS6 | integrator complex subunit 6 | -0.0409208 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0404069 |
| NABP1 | nucleic acid binding protein 1 | -0.0402945 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0400873 |
| HMGA1 | high mobility group AT-hook 1 | -0.0394217 |
| ZNF804A | zinc finger protein 804A | -0.0392697 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0392695 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0390153 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0376158 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0365307 |
| MSR1 | macrophage scavenger receptor 1 | -0.0364744 |
| NAV1 | neuron navigator 1 | -0.0362964 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0342518 |
| MT2A | metallothionein 2A | -0.0334376 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0333483 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.032908 |
| VCL | vinculin | -0.0328586 |
| POTEF | POTE ankyrin domain family, member F | -0.0322841 |
| GPHN | gephyrin | -0.0322533 |
| NF1 | neurofibromin 1 | -0.0319657 |
| MAP4 | microtubule-associated protein 4 | -0.0315386 |
| KIAA1549L | KIAA1549-like | -0.0314937 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0312112 |
| JMJD1C | jumonji domain containing 1C | -0.0309331 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0309003 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0305049 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0303891 |
| TXNIP | thioredoxin interacting protein | -0.030153 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.02971 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0295347 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0294805 |
| CDH13 | cadherin 13 | -0.0293346 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0288843 |
| PTCHD4 | patched domain containing 4 | -0.0287787 |
| NTM | neurotrimin | -0.0284075 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0282757 |
| NLGN1 | neuroligin 1 | -0.0279932 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0270178 |
| EXOC4 | exocyst complex component 4 | -0.0270054 |
| SP100 | SP100 nuclear antigen | -0.0269301 |
| PHF14 | PHD finger protein 14 | -0.0269276 |
| FOXP1 | forkhead box P1 | -0.0268769 |
| DDAH1 | dimethylarginine dimethylaminohydrolase 1 | -0.0265976 |
| ATM | ATM serine/threonine kinase | -0.0258996 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0254355 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0252773 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0248769 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0248712 |
| HMGA2 | high mobility group AT-hook 2 | -0.0247716 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0246413 |
| PHACTR1 | phosphatase and actin regulator 1 | -0.0246028 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0244052 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0238232 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0237611 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | -0.0232486 |
| RAD51B | RAD51 paralog B | -0.0232246 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0232133 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0229989 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0229574 |
| CDK6 | cyclin-dependent kinase 6 | -0.0224859 |
| RPS6 | ribosomal protein S6 | -0.022306 |
| ERBIN | erbb2 interacting protein | -0.0222718 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0222 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0220425 |
| NETO1 | neuropilin (NRP) and tolloid (TLL)-like 1 | -0.022023 |
| ZNF638 | zinc finger protein 638 | -0.0219756 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0216626 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0214051 |
| WASF2 | WAS protein family, member 2 | -0.0213712 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0213712 |
| ADGRB3 | adhesion G protein-coupled receptor B3 | -0.0213371 |
| MAP1B | microtubule-associated protein 1B | -0.0213194 |
| STAU2 | staufen double-stranded RNA binding protein 2 | -0.0211859 |
| KIAA1217 | KIAA1217 | -0.0211334 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0211042 |
| LRCH3 | leucine-rich repeats and calponin homology (CH) domain containing 3 | -0.0210593 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0204808 |
| NBEA | neurobeachin | -0.0203814 |
| MMP16 | matrix metallopeptidase 16 (membrane-inserted) | -0.0203363 |
| EXOC6B | exocyst complex component 6B | -0.0201177 |
