| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| KRT8 | keratin 8, type II | 0.190443 |
| PTMA | prothymosin, alpha | 0.117204 |
| NDRG1 | N-myc downstream regulated 1 | 0.117034 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.111598 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.103379 |
| KRT18 | keratin 18, type I | 0.0995042 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0950568 |
| EZR | ezrin | 0.0800662 |
| VEGFA | vascular endothelial growth factor A | 0.0796733 |
| FAM13A | family with sequence similarity 13, member A | 0.0784728 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0784053 |
| TMSB10 | thymosin beta 10 | 0.0713509 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.070254 |
| TNS4 | tensin 4 | 0.0702344 |
| FLNB | filamin B, beta | 0.0682078 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0666904 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.065713 |
| ANXA2 | annexin A2 | 0.0627418 |
| PGK1 | phosphoglycerate kinase 1 | 0.0614474 |
| TMSB4X | thymosin beta 4, X-linked | 0.0592179 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0589356 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0574695 |
| FAT1 | FAT atypical cadherin 1 | 0.0571751 |
| CCNY | cyclin Y | 0.0557439 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0527709 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0496246 |
| ITGB4 | integrin, beta 4 | 0.0485926 |
| RNF43 | ring finger protein 43 | 0.0485286 |
| PLEC | plectin | 0.0484925 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0464067 |
| ACTN4 | actinin, alpha 4 | 0.0453006 |
| MLEC | malectin | 0.045051 |
| RPL35A | ribosomal protein L35a | 0.0447741 |
| ANXA11 | annexin A11 | 0.0443414 |
| EPHA2 | EPH receptor A2 | 0.0439564 |
| DNM2 | dynamin 2 | 0.0431585 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0422375 |
| ONECUT3 | one cut homeobox 3 | 0.0408817 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0407403 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0394013 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0391725 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0389753 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0387336 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0381949 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0379182 |
| MINK1 | misshapen-like kinase 1 | 0.0378088 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.037649 |
| WDR45B | WD repeat domain 45B | 0.0372382 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0368421 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0364743 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.036389 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0351511 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0346395 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0342282 |
| RPL3 | ribosomal protein L3 | 0.03347 |
| ITGA6 | integrin, alpha 6 | 0.0331734 |
| MED13L | mediator complex subunit 13-like | 0.0329411 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0327563 |
| CTBP2 | C-terminal binding protein 2 | 0.0320917 |
| PPARG | peroxisome proliferator-activated receptor gamma | 0.031802 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0316378 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0305381 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0304182 |
| RREB1 | ras responsive element binding protein 1 | 0.0303011 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0301507 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0299042 |
| LAMB3 | laminin, beta 3 | 0.029747 |
| RNF145 | ring finger protein 145 | 0.0291866 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0283618 |
| NONO | non-POU domain containing, octamer-binding | 0.028354 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0280697 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0278079 |
| ARHGEF10L | Rho guanine nucleotide exchange factor (GEF) 10-like | 0.027487 |
| ABHD2 | abhydrolase domain containing 2 | 0.0273905 |
| AFDN | afadin, adherens junction formation factor | 0.0270172 |
| CD9 | CD9 molecule | 0.0267962 |
| MXD1 | MAX dimerization protein 1 | 0.0265996 |
| KDM4B | lysine (K)-specific demethylase 4B | 0.0259583 |
| GPA33 | glycoprotein A33 (transmembrane) | 0.0257354 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0257154 |
| LMNA | lamin A/C | 0.0252983 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0250774 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0250682 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.024779 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0246625 |
| RPL13A | ribosomal protein L13a | 0.0246613 |
| CD46 | CD46 molecule, complement regulatory protein | 0.0244048 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | 0.024247 |
| FOSL1 | FOS-like antigen 1 | 0.0242389 |
| NUP58 | nucleoporin 58 | 0.0242069 |
| HRNR | hornerin | 0.0240787 |
| PFKFB3 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 0.023827 |
| MSI2 | musashi RNA-binding protein 2 | 0.0238194 |
| LGALS4 | lectin, galactoside-binding, soluble, 4 | 0.0236186 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0235289 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0234097 |
| RLF | rearranged L-myc fusion | 0.0233321 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0233246 |
| OGA | O-GlcNAcase | 0.0232169 |
| S100A14 | S100 calcium binding protein A14 | 0.0230468 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.410029 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.109225 |
| RPS2 | ribosomal protein S2 | -0.0887554 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0682939 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0648462 |
| MYO1E | myosin IE | -0.0616945 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0609003 |
| UBC | ubiquitin C | -0.0514065 |
| POTEF | POTE ankyrin domain family, member F | -0.04903 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0430025 |
| RPS27A | ribosomal protein S27a | -0.0418853 |
| AREG | amphiregulin | -0.0379184 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0376504 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0365613 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0365323 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0357446 |
| VCL | vinculin | -0.0354711 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0342779 |
| CD44 | CD44 molecule (Indian blood group) | -0.033532 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.032945 |
| RAB10 | RAB10, member RAS oncogene family | -0.0328219 |
| TRIM2 | tripartite motif containing 2 | -0.0319697 |
| USP53 | ubiquitin specific peptidase 53 | -0.0311413 |
| VMP1 | vacuole membrane protein 1 | -0.0307053 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0305343 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0304679 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0303335 |
| NEBL | nebulette | -0.0296938 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0286275 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.026352 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0260161 |
| TUBB4B | tubulin, beta 4B class IVb | -0.0257507 |
| ASPH | aspartate beta-hydroxylase | -0.0256526 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0254121 |
| PDIA4 | protein disulfide isomerase family A, member 4 | -0.0252878 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0252065 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0245234 |
| CLTC | clathrin, heavy chain (Hc) | -0.0240846 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0239069 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.023794 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | -0.0236616 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0232113 |
| PAPOLA | poly(A) polymerase alpha | -0.0231768 |
| RPS23 | ribosomal protein S23 | -0.0231101 |
| PDZD8 | PDZ domain containing 8 | -0.0225433 |
| POF1B | premature ovarian failure, 1B | -0.0224357 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0223537 |
| FTL | ferritin, light polypeptide | -0.0223353 |
| MUC17 | mucin 17, cell surface associated | -0.022054 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0214822 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0207915 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0203739 |
| KIAA2026 | KIAA2026 | -0.0198126 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.019754 |
| MAGI3 | membrane associated guanylate kinase, WW and PDZ domain containing 3 | -0.0196777 |
| DSG2 | desmoglein 2 | -0.0195864 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0193877 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0193025 |
| CDK13 | cyclin-dependent kinase 13 | -0.0192585 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0192094 |
| GOLGB1 | golgin B1 | -0.0191297 |
| PALLD | palladin, cytoskeletal associated protein | -0.0189648 |
| MTDH | metadherin | -0.0188712 |
| RPL9 | ribosomal protein L9 | -0.0187963 |
| RPS15 | ribosomal protein S15 | -0.0187464 |
| FHIT | fragile histidine triad | -0.0185707 |
| MAP4 | microtubule-associated protein 4 | -0.0185017 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0182762 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0182089 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0179974 |
| ROCK2 | Rho-associated, coiled-coil containing protein kinase 2 | -0.0178078 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0177693 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0174753 |
| CCNI | cyclin I | -0.0174161 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0173373 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0171516 |
| RPS5 | ribosomal protein S5 | -0.0171372 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0170347 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | -0.0168976 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.016872 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0167843 |
| SELENOF | selenoprotein F | -0.0166838 |
| EXOC6B | exocyst complex component 6B | -0.0165818 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0165612 |
| RPS3 | ribosomal protein S3 | -0.0165505 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0165466 |
| AHI1 | Abelson helper integration site 1 | -0.016507 |
| HMGA1 | high mobility group AT-hook 1 | -0.0164439 |
| RBM25 | RNA binding motif protein 25 | -0.0163286 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0161577 |
| STAU1 | staufen double-stranded RNA binding protein 1 | -0.0160988 |
| SSR1 | signal sequence receptor, alpha | -0.0159099 |
| EGFR | epidermal growth factor receptor | -0.0158908 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0158488 |
| ARFGEF3 | ARFGEF family member 3 | -0.0157238 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | -0.0155289 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | -0.0155203 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | -0.0154847 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0153643 |
| TUBA1B | tubulin, alpha 1b | -0.0152002 |
