| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Fumaric acid perturbation in LoVo cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Fumaric acid_LoVo drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.188704 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.150219 |
| KRT8 | keratin 8, type II | 0.149622 |
| FAT1 | FAT atypical cadherin 1 | 0.138722 |
| RPL3 | ribosomal protein L3 | 0.125055 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.124201 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.121798 |
| FLNB | filamin B, beta | 0.100225 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.09915 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0947951 |
| KRT18 | keratin 18, type I | 0.0914592 |
| EZR | ezrin | 0.0825223 |
| ANXA11 | annexin A11 | 0.0822464 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0778184 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0720646 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0703979 |
| EPHA2 | EPH receptor A2 | 0.0681526 |
| ANXA2 | annexin A2 | 0.0667007 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0648501 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0629317 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0562601 |
| DSPP | dentin sialophosphoprotein | 0.0545358 |
| LAMB3 | laminin, beta 3 | 0.0535404 |
| NONO | non-POU domain containing, octamer-binding | 0.0530279 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0513369 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0512889 |
| ACTG1 | actin gamma 1 | 0.0501007 |
| TMSB10 | thymosin beta 10 | 0.0488367 |
| HLA-B | major histocompatibility complex, class I, B | 0.048107 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0478239 |
| CTBP2 | C-terminal binding protein 2 | 0.0473655 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0452254 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0440854 |
| PLEC | plectin | 0.043848 |
| ACTN4 | actinin, alpha 4 | 0.0438091 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0437044 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0424797 |
| MYO5B | myosin VB | 0.0424217 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0400888 |
| ITGB4 | integrin, beta 4 | 0.0400638 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase | 0.040027 |
| ITGA6 | integrin, alpha 6 | 0.0396358 |
| SORL1 | sortilin-related receptor, L(DLR class) A repeats containing | 0.0393913 |
| PCBP2 | poly(rC) binding protein 2 | 0.0388291 |
| RPL37 | ribosomal protein L37 | 0.0387088 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0373368 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0361689 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0351885 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.035017 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0347033 |
| AFDN | afadin, adherens junction formation factor | 0.034461 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0343347 |
| MLEC | malectin | 0.0338624 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0337095 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0332004 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.032875 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | 0.032713 |
| VEGFA | vascular endothelial growth factor A | 0.0326963 |
| PKM | pyruvate kinase, muscle | 0.0322956 |
| DNM2 | dynamin 2 | 0.0322428 |
| BCL2L1 | BCL2-like 1 | 0.0319521 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0318956 |
| EWSR1 | EWS RNA-binding protein 1 | 0.0306484 |
| SEPTIN2 | septin 2 | 0.0299726 |
| MSI2 | musashi RNA-binding protein 2 | 0.0299105 |
| KLF3 | Kruppel-like factor 3 (basic) | 0.0297476 |
| LDHA | lactate dehydrogenase A | 0.0295542 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0294491 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0291213 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0290942 |
| RPL23 | ribosomal protein L23 | 0.0289393 |
| JUN | jun proto-oncogene | 0.0283909 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0282696 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0280254 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0277477 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.027683 |
| YBX1 | Y box binding protein 1 | 0.0276718 |
| PRELID2 | PRELI domain containing 2 | 0.0275847 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0274098 |
| SLK | STE20-like kinase | 0.0273453 |
| MINK1 | misshapen-like kinase 1 | 0.0271259 |
| SLTM | SAFB-like, transcription modulator | 0.0270948 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0267239 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0267233 |
| PRELID3B | PRELI domain containing 3B | 0.0261109 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0259904 |
| HLA-C | major histocompatibility complex, class I, C | 0.025951 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0258815 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0258317 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0257906 |
| CD9 | CD9 molecule | 0.0256302 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 0.0252969 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0252277 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0249034 |
| GOLGA3 | golgin A3 | 0.0247867 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0245235 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0241894 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | 0.024136 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0240393 |
| SON | SON DNA binding protein | 0.0236472 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.18197 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.110504 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0958615 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0817506 |
| RPLP1 | ribosomal protein, large, P1 | -0.0667583 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0658772 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0641974 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0604067 |
| RPS2 | ribosomal protein S2 | -0.0528512 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0510439 |
| RPS8 | ribosomal protein S8 | -0.0499686 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.0450039 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0448439 |
| PTPRR | protein tyrosine phosphatase, receptor type, R | -0.0442914 |
| CANX | calnexin | -0.0438439 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0435323 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0404038 |
| EREG | epiregulin | -0.0398225 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0387987 |
| SMCHD1 | structural maintenance of chromosomes flexible hinge domain containing 1 | -0.038269 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0374401 |
| RPS23 | ribosomal protein S23 | -0.0360849 |
| CDK13 | cyclin-dependent kinase 13 | -0.0358386 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0353763 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0352381 |
| PPP1CC | protein phosphatase 1, catalytic subunit, gamma isozyme | -0.0352189 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0336773 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0336221 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0330761 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0317804 |
| CCNI | cyclin I | -0.0310597 |
| RPS27A | ribosomal protein S27a | -0.0305646 |
| GOLGA4 | golgin A4 | -0.0304335 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0304176 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0298537 |
| BPTF | bromodomain PHD finger transcription factor | -0.0297797 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.029291 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0292714 |
| MYO1E | myosin IE | -0.0290635 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0290116 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0289873 |
| RPL34 | ribosomal protein L34 | -0.0289669 |
| RPL32 | ribosomal protein L32 | -0.0289205 |
| RPL14 | ribosomal protein L14 | -0.0288113 |
| TCF12 | transcription factor 12 | -0.028778 |
| GDF15 | growth differentiation factor 15 | -0.028745 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0285393 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0284383 |
| RPL5 | ribosomal protein L5 | -0.0284059 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0283166 |
| COG5 | component of oligomeric golgi complex 5 | -0.0281603 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0281367 |
| MTDH | metadherin | -0.0280748 |
| RPS15 | ribosomal protein S15 | -0.0280474 |
| GPHN | gephyrin | -0.0280002 |
| TBCA | tubulin folding cofactor A | -0.0273297 |
| RPS24 | ribosomal protein S24 | -0.0268514 |
| SLC38A2 | solute carrier family 38, member 2 | -0.026792 |
| SP100 | SP100 nuclear antigen | -0.0267414 |
| MAN2A1 | mannosidase, alpha, class 2A, member 1 | -0.0266951 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0255044 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0251036 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0249747 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.024754 |
| RTN3 | reticulon 3 | -0.0244616 |
| RIGI | RNA sensor RIG-I | -0.0242831 |
| DEK | DEK proto-oncogene | -0.0240398 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0239302 |
| CADPS2 | Ca++-dependent secretion activator 2 | -0.0239176 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0236449 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0236133 |
| NSD3 | nuclear receptor binding SET domain protein 3 | -0.0234957 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0234518 |
| PCDHB16 | protocadherin beta 16 | -0.0234384 |
| GOLM2 | golgi membrane protein 2 | -0.0233595 |
| PHF14 | PHD finger protein 14 | -0.0233159 |
| FOXP1 | forkhead box P1 | -0.0232905 |
| RIMKLB | ribosomal modification protein rimK-like family member B | -0.023199 |
| IER3 | immediate early response 3 | -0.0231296 |
| MAP4 | microtubule-associated protein 4 | -0.0230097 |
| DMGDH | dimethylglycine dehydrogenase | -0.0227905 |
| GOLGB1 | golgin B1 | -0.0227288 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0227166 |
| PLSCR1 | phospholipid scramblase 1 | -0.0226079 |
| AGR2 | anterior gradient 2 | -0.0226057 |
| TMEM263 | transmembrane protein 263 | -0.0225839 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0222722 |
| RFX3 | regulatory factor X, 3 (influences HLA class II expression) | -0.0221633 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.022151 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0220341 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0219791 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0218267 |
| RPL4 | ribosomal protein L4 | -0.0217561 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0216435 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0215433 |
| RPL8 | ribosomal protein L8 | -0.0213179 |
| RPS11 | ribosomal protein S11 | -0.0209733 |
| NF1 | neurofibromin 1 | -0.0209058 |
| USP15 | ubiquitin specific peptidase 15 | -0.0208733 |
| RPS29 | ribosomal protein S29 | -0.0206442 |
